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Management of
Difficult Airway
                 ABDEL H NOURELDIN
                  PROGRAM DIRECTOR
           CHAIRMAN SCIENTIFIC COMMITTEE
      EMIRATES SOCIETY OF EMERGENCY MEDICINE
TAWAM HOSPITAL EMERGENCY MEDICINE RESIDENCY PROGRAM
               ICEM – DECEMBER -2012
SHOW THE VIDEO
EMERGENCY AIRWAY HAS TO MANAGED

 PLAN A



 PLAN B




 PLAN Z
What do we need for any airway?




                 Good
 Time            Oxygen
                  Saturation
                 96 t0 99%
Figure 1
AIRWAY MANAGEMENT

PAST (12 YEARS AGO)                      Current
 (RSI) was used in 83.6% time              RSI was used 86.2% time

 succinylcholine was used as a             Now it is only 40.5% of the cases
    paralytic in 92.0% of the cases,         (p<0.01). Rocoronium is used as a
                                             paralytic in 58.6%
   Etomidate is used as an induction
    agent 82.5%                             Etomidate is used 90.4% (p<0.01).

 direct laryngoscopy (DL) in 98.7% of      DL declined to 57.2% (p<0.01).
    the patients.                            Videolaryngoscopes, accounted for
                                             38.9%
 The failed airway rate: declined        The failed airway rate: 0.2%
    from 1.1%                                (p<0.05).
SOURCE OF HIGH FIO2
          Dr. Weingart and Levitan -
  Annals of Emergency Medicine – March -2012




 None Rebreather       MORE THAN
 mask at 15              15L/MINUTES
 liter/minute gives      CAN DELIVER
 you 60% to 70%          ABOUT 90% FIO2
 FIO2
TIME FOR PREOXYGENATION
          Dr. Weingart and Levitan -
  Annals of Emergency Medicine – March -2012
                       SICK &
COOPERATIVE            UNCOOPERATIVE
PATIENTS
                       PATIENTS

8 BREATH 3 MINUTES
60 SECONDS
PREOXYGENATION
BAILLARD ET ALL-EXAMINED HYPOXIC CRITICALLY ILL
                    IN ICU
– NIPPV ( none invasive
                                 Standard ventilation
positive pressure ventilation)
 The mean O2 Sat of              The mean O2 Sat of 93%
  98%                            ( 6 patient had to have NIPPV)


 During intubation:              During intubation
  desaturated to 93%               :desaturated to 81%


 2 patients desaturated          2 patients desaturated
  below 80%                        below 80%
A disposable PEEP valve.PEEP settings
         from 5 to 20 cm H2O.

                     If combined with a nasal
                     cannula set to 15 L/minute, it will
                     provide CPAP even
                     without ventilations.
PREOXYGENATION
 If you can not get O2 sat to 93% to
 95% with high flow O2

 Use NIPPV with pressure less 25 cm
 H2O
HEAD POSITION
  LANE ET AL- ANESTHESIA 2005
20 degree
head up       supine
 desaturated desaturated
  to 95% in    to 95% in
  386 seconds 283 seconds
 103 seconds
HEAD POSITION
 ALTERMATT ET AL- BR.J. ANESTH 2005
Body mass index >35   Body mass index >35
sitting               supine
desaturated desaturated
 to 90% in             to 90% in
 214 seconds           162 seconds
52 seconds
HEAD POSITION
   Dixon ET AL- ANESTHESIA 2005
Body mass index >40 Body mass index >40
25 degree up        supine

 showed
 similar
 benefit
HEAD POSITION
 RAMKUMAR ET AL- J. ANESTH 2011
20 degree
head up          supine
desaturated desaturated
 to 95% in        to 95% in
 452 seconds      364 seconds
88 seconds
PASSIVE APNIEC OXYGENATION
 Apneic oxygenation is not a new
 concept:
> 100 years old concept:
 Apneic diffusion oxygenation,
 Diffusion respiration
 Mass flow ventilation
PASSIVE     APNIEC OXYGENATION

 In an apneic patient:
 250 mL/minute of oxygen will
  move from the alveoli into the
  bloodstream.
 8 to 20 mL/minute of carbon
  dioxide moves into the alveoli
  during apnea
PASSIVE            APNIEC OXYGENATION

 In an apneic patient:
    net pressure in the alveoli to become slightly
    subatmospheric, generating a mass flow of gas
    from pharynx to alveoli.

 PaO2 can be maintained at greater than 100
mm Hg for up to 100 minutes without a single
 breath,
PASSIVE     APNIEC OXYGENATION
TAHA ET AL- ANESTHESIA - 2006
O2 AT 5 L/MINUTE VIA
                       CONTROL GROUP
NASAL CANULA

NO                     DEXATURATI
 DESATURA               ON TO 95%
 TION FOR 6             AT 3.65
                        MINUTES
 MINUTES
                        AVERAGE
PASSIVE        APNIEC OXYGENATION
RAMACHANDRAN ET AL- CLIN. J. ANESTHESIA - 2010

OBESE PATIENTS: O2 AT 5     OBESE PATIENTS:
L/MINUTE VIA NASAL CANULA   CONTROL GROUP
DESATURATION TO 95 %         DEXATURATION TO 95%
  OR MORE FOR 5.29            OR LESS FOR 3.49
  MINUTES                     MINUTES AVERAGE

8 PATIENT HAD O2 SAT. >      I PATIENT HAD O2 SAT >.
  95%                         95%

MINIMUM SPO2 94.3%           MINIMUM SPO2 %87.7
PASSIVE   APNIEC OXYGENATION

15 L / min. via nasal
catheter during the
induction and
muscle relaxant
Direct laryng. vs video laryng.
                   MAY – 2012
                 750 INTUBATION




 1st attempt. Success    1st attempt. Success
  rate     84.4%           rate   97.3%

Cormack – Lehane grade   Cormack – Lehane grade
 I & II view 82.8%        I & II view 93.6%.
ROCURONIUM VS SUCCINYLCHOLINE

ROCURONIUM                SUCCINYLCHOLINE
 Time to desaturate to    Time to desaturate to
 95% Was 378 seconds       95% Was 242 seconds

 Obese patient time to    Obese patient time to
 desaturate to 92% was     desaturate to 92% was
 329 seconds               283 seconds
Sugammadex
                Anesth Analg 2007;104:569 –74)

    Sugammadex, 4 mg/kg IV, more rapidly and effectively
    reversed residual neuromuscular blockade when
    compared with neostigmine (70 g/kg IV) and drophonium
    (1 mg/kg IV).

 Use of sugammadex was associated with less frequent dry
  mouth than that with the currently used reversal drug
  combination
ROCURONIUM VS SUCCINYLCHOLINE
 Roc. Dose of 1.2 produced
  excellent intubation condition at
  40 seconds
 Roc. Can be reverse with
  sugmmadex in few seconds
 In difficult intubation it give more
  time to intubate the patient .
Sugammadex for Rocuronium
25 y/o female with h/o asthma, was
brought by paramedics, combative
pulling her O2 mask off and her O2
sat 85%
35 y/o male who drank chlorax at work accidently,
complain of dyspnea and has strider.
Vital are normal and O2 sat 92% on 100% oxygen
Believe in yourself
THANK
  YOU

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Management of Difficult Airway

  • 1. Management of Difficult Airway ABDEL H NOURELDIN PROGRAM DIRECTOR CHAIRMAN SCIENTIFIC COMMITTEE EMIRATES SOCIETY OF EMERGENCY MEDICINE TAWAM HOSPITAL EMERGENCY MEDICINE RESIDENCY PROGRAM ICEM – DECEMBER -2012
  • 3. EMERGENCY AIRWAY HAS TO MANAGED  PLAN A  PLAN B  PLAN Z
  • 4. What do we need for any airway? Good Time Oxygen Saturation 96 t0 99%
  • 5.
  • 7. AIRWAY MANAGEMENT PAST (12 YEARS AGO) Current  (RSI) was used in 83.6% time  RSI was used 86.2% time  succinylcholine was used as a  Now it is only 40.5% of the cases paralytic in 92.0% of the cases, (p<0.01). Rocoronium is used as a paralytic in 58.6%  Etomidate is used as an induction agent 82.5%  Etomidate is used 90.4% (p<0.01).  direct laryngoscopy (DL) in 98.7% of  DL declined to 57.2% (p<0.01). the patients. Videolaryngoscopes, accounted for 38.9%  The failed airway rate: declined  The failed airway rate: 0.2% from 1.1% (p<0.05).
  • 8. SOURCE OF HIGH FIO2 Dr. Weingart and Levitan - Annals of Emergency Medicine – March -2012  None Rebreather  MORE THAN mask at 15 15L/MINUTES liter/minute gives CAN DELIVER you 60% to 70% ABOUT 90% FIO2 FIO2
  • 9. TIME FOR PREOXYGENATION Dr. Weingart and Levitan - Annals of Emergency Medicine – March -2012 SICK & COOPERATIVE UNCOOPERATIVE PATIENTS PATIENTS 8 BREATH 3 MINUTES 60 SECONDS
  • 10. PREOXYGENATION BAILLARD ET ALL-EXAMINED HYPOXIC CRITICALLY ILL IN ICU – NIPPV ( none invasive Standard ventilation positive pressure ventilation)  The mean O2 Sat of  The mean O2 Sat of 93% 98% ( 6 patient had to have NIPPV)  During intubation:  During intubation desaturated to 93% :desaturated to 81%  2 patients desaturated  2 patients desaturated below 80% below 80%
  • 11. A disposable PEEP valve.PEEP settings from 5 to 20 cm H2O. If combined with a nasal cannula set to 15 L/minute, it will provide CPAP even without ventilations.
  • 12. PREOXYGENATION  If you can not get O2 sat to 93% to 95% with high flow O2  Use NIPPV with pressure less 25 cm H2O
  • 13. HEAD POSITION LANE ET AL- ANESTHESIA 2005 20 degree head up supine  desaturated desaturated to 95% in to 95% in 386 seconds 283 seconds  103 seconds
  • 14. HEAD POSITION ALTERMATT ET AL- BR.J. ANESTH 2005 Body mass index >35 Body mass index >35 sitting supine desaturated desaturated to 90% in to 90% in 214 seconds 162 seconds 52 seconds
  • 15. HEAD POSITION Dixon ET AL- ANESTHESIA 2005 Body mass index >40 Body mass index >40 25 degree up supine  showed similar benefit
  • 16. HEAD POSITION RAMKUMAR ET AL- J. ANESTH 2011 20 degree head up supine desaturated desaturated to 95% in to 95% in 452 seconds 364 seconds 88 seconds
  • 17.
  • 18.
  • 19. PASSIVE APNIEC OXYGENATION  Apneic oxygenation is not a new concept: > 100 years old concept:  Apneic diffusion oxygenation,  Diffusion respiration  Mass flow ventilation
  • 20. PASSIVE APNIEC OXYGENATION  In an apneic patient:  250 mL/minute of oxygen will move from the alveoli into the bloodstream.  8 to 20 mL/minute of carbon dioxide moves into the alveoli during apnea
  • 21. PASSIVE APNIEC OXYGENATION  In an apneic patient:  net pressure in the alveoli to become slightly subatmospheric, generating a mass flow of gas from pharynx to alveoli.  PaO2 can be maintained at greater than 100 mm Hg for up to 100 minutes without a single breath,
  • 22. PASSIVE APNIEC OXYGENATION TAHA ET AL- ANESTHESIA - 2006 O2 AT 5 L/MINUTE VIA CONTROL GROUP NASAL CANULA NO  DEXATURATI DESATURA ON TO 95% TION FOR 6 AT 3.65 MINUTES MINUTES AVERAGE
  • 23. PASSIVE APNIEC OXYGENATION RAMACHANDRAN ET AL- CLIN. J. ANESTHESIA - 2010 OBESE PATIENTS: O2 AT 5 OBESE PATIENTS: L/MINUTE VIA NASAL CANULA CONTROL GROUP DESATURATION TO 95 %  DEXATURATION TO 95% OR MORE FOR 5.29 OR LESS FOR 3.49 MINUTES MINUTES AVERAGE 8 PATIENT HAD O2 SAT. >  I PATIENT HAD O2 SAT >. 95% 95% MINIMUM SPO2 94.3%  MINIMUM SPO2 %87.7
  • 24.
  • 25. PASSIVE APNIEC OXYGENATION 15 L / min. via nasal catheter during the induction and muscle relaxant
  • 26. Direct laryng. vs video laryng. MAY – 2012 750 INTUBATION  1st attempt. Success  1st attempt. Success rate 84.4% rate 97.3% Cormack – Lehane grade Cormack – Lehane grade I & II view 82.8% I & II view 93.6%.
  • 27. ROCURONIUM VS SUCCINYLCHOLINE ROCURONIUM SUCCINYLCHOLINE  Time to desaturate to  Time to desaturate to 95% Was 378 seconds 95% Was 242 seconds  Obese patient time to  Obese patient time to desaturate to 92% was desaturate to 92% was 329 seconds 283 seconds
  • 28. Sugammadex Anesth Analg 2007;104:569 –74)  Sugammadex, 4 mg/kg IV, more rapidly and effectively reversed residual neuromuscular blockade when compared with neostigmine (70 g/kg IV) and drophonium (1 mg/kg IV).  Use of sugammadex was associated with less frequent dry mouth than that with the currently used reversal drug combination
  • 29. ROCURONIUM VS SUCCINYLCHOLINE  Roc. Dose of 1.2 produced excellent intubation condition at 40 seconds  Roc. Can be reverse with sugmmadex in few seconds  In difficult intubation it give more time to intubate the patient .
  • 31.
  • 32. 25 y/o female with h/o asthma, was brought by paramedics, combative pulling her O2 mask off and her O2 sat 85%
  • 33. 35 y/o male who drank chlorax at work accidently, complain of dyspnea and has strider. Vital are normal and O2 sat 92% on 100% oxygen