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Father of genetics
Gregor johann mendel
(1822–1884)
was educated in a monastery
Failure in studies not
suppressed his zeal for
scientific quest
went back to his monastery
and started growing peas
blended his knowledge of
science and mathematics and
was the first one to keep count
of individuals exhibiting a
particular trait in each
generation.
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Why did mendel choose
pea plant for his studies ?
Presence of more observable
contrasting traits
Produces many offspring in one
cross
Ease in manipulating
pollination
Sexually reproduced with
bisexual characters
Self pollination and self
fertilization is possible
Hybrids were perfectly fertile
Life cycle was completed in one
cycle
Takes 70 days to 80 days to
mature (from planting to
eating)
Pea plant binomial name-
Pisum sativum
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All plants were tall
T T t t
Tt Tt
Fusion of
gametes
Punnett square
mathematical count of
individuals exhibiting a
particular trait in each
generation.
Tt
Tt
T T
t Tt Tt
t Tt Tt
Gamete formation -haploid cell (n)
TT tt
All plants were tall
F1-generation of monohybrid cross
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3:1 ratio
T t T t
Fusion of
gametes
Punnett square
mathematical count of
individuals exhibiting a
particular trait in each
generation.
TT tt
Tt
Tt
T t
T TT Tt
t Tt tt
Gamete formation -haploid cell (n)
Tt Tt
3:1 ratio
F2-generation of monohybrid cross
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04F1 generation
Phenotype ratio- 4:0
Genotype ratio- 4:0:0
(heterozygous Tt)
F2 generation
Phenotype ratio- 3:1
Genotype ratio- 1:2:1 ( TT : Tt : tt )
Homozygous –allelic pair of genes
for height are identical (TT)
Heterozygous- allelic pair of genes
for height are non-identical (Tt)
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Mendel’s laws of inheritance
1. Law of Dominance
(i) Characters are controlled by
discrete units called factors.
(ii) Factors occur in pairs.
(iii) In a dissimilar pair of factors
one member of the pair dominates
(dominant) the other (recessive).
The law of dominance is used to
explain the expression of only one
of the parental characters in a
monohybrid cross in the F1 and
the expression of both in the F2. It
also explains the proportion of 3:1
obtained at the F2.
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Mendel’s laws of inheritance
2. Law of segregation
the parents contain two alleles
during gamete formation, the
factors or alleles of a pair segregate
from each other such that a gamete
receives only one of the two factors.
Of course, a homozygous parent
produces all gametes that are
similar while a heterozygous one
produces two kinds of gametes
each having one allele with equal
proportion.
In simple- alleles get separated
during gamete formation (one
allele in each gamete)
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Tt ? ? Tt
Tt Tt
If alleles are not separated during
gamete formation !!!!
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What happens when pea plants
showing two different
characteristics, rather than just
one, are bred with each other?
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Gamete formation in Parent
Ry Ry rY rY
RR yy rr YY
RyrY RyrY
RyrY
RyrY
(F1)
generation
Gamete formation in F1
generation
RY Ry rY ry
RY RYRY RYRy RYrY RYry
Ry RyRY RyRy RyrY Ryry
rY RYrY RyrY rYrY rYry
ry RYry Ryry rYry ryry
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Rr Yy
RrYy
If alleles are not separated during
gamete formation !!!!
RY ry
rY
Ry
RrYy
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Mendel’s laws of inheritance
3. Independent assortment
The law states that ‘when two
pairs of traits are combined in a
hybrid, segregation of one pair of
characters is independent of the
other pair of characters’.
Inheritance of one trait in
independent of the other traits
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Sex determination
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