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Extrapyramidal tracts
Dr. Sai Sailesh Kumar G
Associate Professor
Department of Physiology
NRIIMS
Email: dr.goothy@gmail.com
Reticulospinal tracts
Throughout the midbrain, pons and medulla, groups of scattered
nerve cells and nerve fibers exist that are collectively known as
the reticular formation
From the pons, these neurons send axons
Mostly uncrossed
Down into the spinal cord – pontine reticular tract
Reticulospinal tracts
 From medulla, similar neurons send axons
 Crossed and uncrossed
 Medullary reticulospinal tract
 Reticulospinal fibers from pons descend through the anterior white column
 Medullary reticulospinal tract descends through the lateral white column
Reticulospinal tracts
Both sets of fibers enter anterior gray column of spinal cord
and may facilitate or inhibit the activity of alpha and gamma
motor neurons
Reticulospinal tract influence voluntary movements and
reflex activity.
Tectospinal tracts
Fibers from this tract arise from nerve cells in the superior
colliculus of the mid brain
Most of the fibers cross the midline soon after their origin and
descend through the brainstem close to the medial
longitudinal fasciculus
Tectospinal tracts
Descends through the anterior white column of the spinal
cord close to the anterior median fissure
Majority of fibers terminates in the anterior gray column by
synapsing with inter neurons
Concerned with reflex postural movements in response to
visual stimuli
Rubrospinal tract
The red nucleus is situated in the tegmentum of the midbrain
The axons of the neurons in this nucleus cross midline at the
level of the nucleus and
descend as rubrospinal tract through pons and medulla
to enter the lateral white column of spinal cord
Terminates on interneurons at anterior gray column
Rubrospinal tract
Considered as important indirect pathway by which the
cerebral cortex and the cerebellum can influence the
activity of alpha and gamma motor neurons of the spinal
cord.
Vestibulospinal tract
The vestibular nucleus is situated in the pons and medulla
The vestibular nuclei receive afferents from inner ear and
cerebellum
The neurons of lateral vestibular nucleus give rise to the axons
that form the vestibulospinal tract
The tract descends uncrossed
Vestibulospinal tract
Descends through medulla
Enter spinal cord in the anterior white column
Terminates by synapsing with inter neurons of anterior gray
column
This tract facilitates the activity of extensor muscles and inhibits
the activity of flexor muscles- maintenance of balance
Olivospinal tract
Arise from the inferior olivary nucleus
Descends in the lateral white column of the spinal cord
Influence activity of the motor neurons in the anterior gray
column
There is now considerable doubt that this tract exists..
Upper Motor Neuron lesion
Lesions of corticospinal tract (pyramidal tract)
Lesions restricted to corticospinal tracts produce the following
clinical signs
Babinski sign is present – great toe is dorsi flexed and
fanning of other toes – Plantar extensor response
Upper Motor Neuron lesion
Superficial abdominal reflexes are absent
Cremasteric reflex is absent
Loss of performance of fine skilled voluntary movements
Upper Motor Neuron lesion
Lesions of descending tracts other than pyramidal tract (
extrapyramidal tract lesion)
Severe paralysis- with little or no muscle atrophy
Spasticity or hypertonicity of muscles – lower limb is
maintained extension. Upper limb is maintained in flexion
Upper Motor Neuron lesion
Exaggerated deep muscle reflexes
Clasp knife reaction
Upper Motor Neuron lesion
In clinical practice it is rare to have organic lesion that is
restricted only to pyramidal tracts or only extra pyramidal
tracts
Usually both sets of tracts are affected to variable extent
producing both group of clinical signs
Lower Motor Neuron lesion
Trauma, infection (poliomyelitis), vascular disorders, and
degeneration may produce lesion of lower motor neuron by
destroying the cell body of anterior gray column
Lower Motor Neuron lesion
Flaccid paralysis of muscles supplied
Atrophy
Loss of reflexes
Muscle contracture
Reaction of degeneration
Types of paralysis
Hemiplegia – paralysis of one side of body and includes the
upper limb , one side trunk and lower limb
Monoplegia –paralysis of one limb only
Paraplegia – paralysis of the two lower limbs
Diplegia – paralysis of two corresponding limbs
Quadriplegia – paralysis of all four limbs
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Extra pyramidal tracts.pptx

  • 1. Extrapyramidal tracts Dr. Sai Sailesh Kumar G Associate Professor Department of Physiology NRIIMS Email: dr.goothy@gmail.com
  • 2. Reticulospinal tracts Throughout the midbrain, pons and medulla, groups of scattered nerve cells and nerve fibers exist that are collectively known as the reticular formation From the pons, these neurons send axons Mostly uncrossed Down into the spinal cord – pontine reticular tract
  • 3. Reticulospinal tracts  From medulla, similar neurons send axons  Crossed and uncrossed  Medullary reticulospinal tract  Reticulospinal fibers from pons descend through the anterior white column  Medullary reticulospinal tract descends through the lateral white column
  • 4. Reticulospinal tracts Both sets of fibers enter anterior gray column of spinal cord and may facilitate or inhibit the activity of alpha and gamma motor neurons Reticulospinal tract influence voluntary movements and reflex activity.
  • 5.
  • 6. Tectospinal tracts Fibers from this tract arise from nerve cells in the superior colliculus of the mid brain Most of the fibers cross the midline soon after their origin and descend through the brainstem close to the medial longitudinal fasciculus
  • 7. Tectospinal tracts Descends through the anterior white column of the spinal cord close to the anterior median fissure Majority of fibers terminates in the anterior gray column by synapsing with inter neurons Concerned with reflex postural movements in response to visual stimuli
  • 8.
  • 9. Rubrospinal tract The red nucleus is situated in the tegmentum of the midbrain The axons of the neurons in this nucleus cross midline at the level of the nucleus and descend as rubrospinal tract through pons and medulla to enter the lateral white column of spinal cord Terminates on interneurons at anterior gray column
  • 10. Rubrospinal tract Considered as important indirect pathway by which the cerebral cortex and the cerebellum can influence the activity of alpha and gamma motor neurons of the spinal cord.
  • 11.
  • 12. Vestibulospinal tract The vestibular nucleus is situated in the pons and medulla The vestibular nuclei receive afferents from inner ear and cerebellum The neurons of lateral vestibular nucleus give rise to the axons that form the vestibulospinal tract The tract descends uncrossed
  • 13. Vestibulospinal tract Descends through medulla Enter spinal cord in the anterior white column Terminates by synapsing with inter neurons of anterior gray column This tract facilitates the activity of extensor muscles and inhibits the activity of flexor muscles- maintenance of balance
  • 14.
  • 15. Olivospinal tract Arise from the inferior olivary nucleus Descends in the lateral white column of the spinal cord Influence activity of the motor neurons in the anterior gray column There is now considerable doubt that this tract exists..
  • 16.
  • 17. Upper Motor Neuron lesion Lesions of corticospinal tract (pyramidal tract) Lesions restricted to corticospinal tracts produce the following clinical signs Babinski sign is present – great toe is dorsi flexed and fanning of other toes – Plantar extensor response
  • 18. Upper Motor Neuron lesion Superficial abdominal reflexes are absent Cremasteric reflex is absent Loss of performance of fine skilled voluntary movements
  • 19. Upper Motor Neuron lesion Lesions of descending tracts other than pyramidal tract ( extrapyramidal tract lesion) Severe paralysis- with little or no muscle atrophy Spasticity or hypertonicity of muscles – lower limb is maintained extension. Upper limb is maintained in flexion
  • 20. Upper Motor Neuron lesion Exaggerated deep muscle reflexes Clasp knife reaction
  • 21. Upper Motor Neuron lesion In clinical practice it is rare to have organic lesion that is restricted only to pyramidal tracts or only extra pyramidal tracts Usually both sets of tracts are affected to variable extent producing both group of clinical signs
  • 22. Lower Motor Neuron lesion Trauma, infection (poliomyelitis), vascular disorders, and degeneration may produce lesion of lower motor neuron by destroying the cell body of anterior gray column
  • 23. Lower Motor Neuron lesion Flaccid paralysis of muscles supplied Atrophy Loss of reflexes Muscle contracture Reaction of degeneration
  • 24. Types of paralysis Hemiplegia – paralysis of one side of body and includes the upper limb , one side trunk and lower limb Monoplegia –paralysis of one limb only Paraplegia – paralysis of the two lower limbs Diplegia – paralysis of two corresponding limbs Quadriplegia – paralysis of all four limbs