This document provides an overview of handheld medical applications and how to ensure compliance with HIPAA regulations when using such applications. It discusses the major operating systems for handheld devices and applications available for each. Examples of applications include e-book readers, medical calculators, drug references and clinical resources. The document also outlines steps to take to secure patient information on handheld devices in accordance with HIPAA and identifies several free and commercial applications and resources available through the library.