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International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 9 143 – 147
_______________________________________________________________________________________________
143
IJRITCC | September 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
A Comparative Study on the Methods Used for the Detection of Breast Cancer
Dr. T. Ramaprabha
Professor, dept. of Computer Science,
Vivekanandha College of arts and science for women
(Autonomous), Namakkal, India.
e-mail: ramaradha1971@gmail.com
T. Sathya priya
Asst.Professor, dept. of Computer Science,
Shri Sakthikailash women's college,
Salem, India
e-mail: sathyapriyapoint@gmail.com
Abstract—Among women in the world, the death caused by the Breast cancer has become the leading role. At an initial stage, the
tumor in the breast is hard to detect. Manual attempt have proven to be time consuming and inefficient in many cases. Hence there
is a need for efficient methods that diagnoses the cancerous cell without human involvement with high accuracy. Mammography
is a special case of CT scan which adopts X-ray method with high resolution film. so that it can detect well the tumors in the
breast. This paper describes the comparative study of the various data mining methods on the detection of the breast cancer by
using image processing techniques.
Keywords-Breast Cancer; Image Processing; Segmentation; Pre-Processing; Mammogram; Machine Learning.
__________________________________________________*****_________________________________________________
I. INTRODUCTION
The main cause of cancer death in women is due to Breast
cancers. Early detection and diagnosis can be done through
digital mammography which prevents the death rate increase
all around the world. Early diagnosis prevents the unwanted
growth of malignant cells which saves the life of the patients.
The abnormalities in the breast are of various types such as
masses, micro calcifications, speculated lesions and
architectural distortions. These abnormalities occur in two
types called begin and malignant. The beginning is non-
cancerous abnormalities whereas the malignant abnormalities
are reported as cancers by the radiologist. The breast masses
normally occurs in the dense regions with different shapes,
which includes shapes such as circumscribed, stellate,
lobulated. They are difficult to detect because of the poor
contrast, different sizes, shapes and the similarity to other
breast muscles, blood vessels, fibrous tissues and breast
parenchymal. The micro calcification occurs in clusters and
they are tiny granules of calcium deposits which usually occur
in the size range 0.1 mm to 0.7 mm with irregular shapes.
The extraction of abnormalities from the digital
mammograms is the main goal of image segmentation
techniques. The segmentation methods consist of the breast
regions segmentation and Regions of interest (ROI)
segmentation. Segmenting the breast region, suppresses the
background of the image and separates the breast regions for
eliminating the surrounding areas which include the muscles,
blood vessels, fibrous tissues and breast parenchymal.
Segmentation of the regions of interest (ROI) is done by
extracting the suspicious candidates which are targets of
cancers by partitioning the image into non-overlapping regions
of interest (ROI). Segmentation is done on single view
mammograms and multi view mammograms. The single view
mammogram segmentation consists of the supervised and
unsupervised methods which includes region. The multi view
mammogram segmentation works on the images of the left and
right breasts, multiple views of the same breast and similar
views taken at different time intervals. The entire segmentation
process also includes the regions with false positives which are
eliminated in the classification stages.
II. BREAST CANCER DETECTION
Early detection has been the rallying cry of breast cancer
from the outset of the response to the disease. While exact
causes of breast cancer are not known, evidence suggests that a
combination of inherited and environmental causes must be
present for it to develop. Efforts to prevent breast cancer are
hampered by the disease’s complexity and the limits of our
current scientific knowledge. Many established risk factors for
breast cancer, including being a woman, aging, breast density,
family history, genetics or a prior breast cancer diagnosis
which cannot be modified. On the upside, evidence
demonstrates that the risk of developing breast cancer can be
reduced by maintaining a healthy body weight, being
physically active, eating well and limiting alcohol
consumption. However, because personal risk reduction is still
no guarantee, early detection has been the ballast of hope and
action for breast cancer. Until we are able to effectively prevent
breast cancer, early detection will remain our leading strategy
for reducing mortality and illness due to the disease. Early
detection means using an approach that aims to diagnose breast
International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 9 143 – 147
_______________________________________________________________________________________________
144
IJRITCC | September 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
cancer earlier than might otherwise occur. Breast cancer
screening sometimes referred to as secondary prevention, is the
routine testing of individuals without symptoms that aims to
detect breast cancer at its earliest stages, so effective treatment
can be offered. Since breast cancer screening began in Canada
in the late 1980s, it is attributed with helping reduce breast
cancer mortality by an estimated 25 - 30 percent.
III. RELATED WORKS ON THE DETECTION OF BREAST
CANCER BY USING DIFFERENT METHODS
The following depicts the different Image Processing and
Data Mining methods for the detection of breast cancer.
The authors ChiranjiLalChowdhary, D. P. Acharjya in
the paper [1], utilizes the Intuitionistic Fuzzy Set, Rough Set,
Indiscernibility Relation, Restricted Equivalence Function
methods for the detection of the breast cancer. In that paper, the
hybrid scheme starts with image segmentation using
intuitionistic fuzzy set to extract the zone of interest and then to
enhance the edges surrounding it. The experimental analysis
shows the overall accuracy of 98.3% and it is higher than the
accuracy achieved by hybridizing fuzzy rough set model.
In the paper [2], the authors Monica, Singh Sanjay
Kumar, AgrawalPrateek, MadaanVishu, used the following
methods Haar Wavelet Transform, Binarization, Segmentation,
Artificial Neural Network. It is observed that the breast images
are analyzed after decomposition. However, the image become
smaller and crucial information may be lost by virtue of image
decomposition and when region of interest is applied only on
the specific segment of image as above said, some information
get lost. Further, the high pass decomposed image using
wavelet transform over enhance the intensity variation that may
be falsely detected and cancer characteristics leading to
erroneous analysis. These limitations could be overcome by
denoising the given input image using the wavelet transform
and analysis made on inverse transformed image. The texture
features should also be considered while analyzing an image
for cancer detection. A back propagation neural network is
trained using the mammogram images in different categories
and tested using the sample as well as unknown images 13
feature neurons are used for N/W training and testing as well.
The N/W is trained for normal images as well as abnormal
cases. The classification accuracy has been observed to the tune
of 89%.
D. Selvathi and A. AarthyPoornila in the paper [3]
used Unsupervised Deep Learning method. The proposed
system uses an unsupervised, deep learning based technique
which uses Mammogram in the detection of breast cancer. The
labeled data serves as the training set and the un-labeled images
are classified with deep-learning nets. The deep network
consists of stacked auto encoder and soft max classifier. The
auto encoder has four hidden layers and a novel
sparsityregularizer which incorporates both population sparsity
and lifetime sparsity. The model is easy to apply and
generalizes to many other scoring problems. The proposed
model has achieved an accuracy of up to 98.5% in classifying
dense mammogram images.
M. Kanchana and P. Varalakshmi in the paper [4]
used Discrete Wavelet Transform, Probabilistic Neural
Network. In this paper initially, the mammography images are
segmented using wavelet based threshold method. The
proposed system provides valuable information to the
radiologists and is helpful in detecting abnormalities faster than
the traditional methods. The proposed Computer Aided
Diagnosis (CAD) system is tested using Mammography Image
Analysis Society (MIAS) database and achieves an accuracy of
92.3%.
In this paper [5], the following methods are used by
the authors, Wavelet decomposition, multi-scale region-
growing, curvature scale space, adaptive mathematical
morphology. In this paper, automatic quantitative image
analysis technique of BCH images is proposed. For the nuclei
segmentation, top bottom hat transform is applied to enhance
image quality. Wavelet decomposition and multi-scale region
growing (WDMR) are combined to obtain regions of interest
(ROIs) there by realizing precise location. A double-strategy
splitting model (DSSM) containing adaptive mathematical
morphology and Curvature Scale Space (CSS) corner detection
method is applied to split over lapped cells for better accuracy
and robustness. For the classification of cell nuclei, 4 shape-
based features and 138 textural features based on color spaces
are extracted. Optimal feature set is obtained by support vector
machine (SVM) with chain-like agent genetic algorithm
(CAGA). The proposed method was tested on 68 BCH images
containing more than 3600cells. Experimental results show that
the mean segmentation sensitivity was 91.53% (74.05%) and
specificity was 91.64% (74.07%). The classification
performance of normal and malignant cell images can achieve
96.19% (70.31%) for accuracy, 99.05% (70.27%) for
sensitivity and 93.33% (70.81%) for specificity.
The authors Harry Strange in the paper [6], used
Manifold Learning method. In this paper, the author said that
there is a strong correlation between relative mammographic
breast density and the risk of developing breast cancer. As
such, accurately modeling the percentage of a mammogram
that is dense is a pivotal step in density based risk
classification. In this work, a novel method based on manifold
learning is used to segment high-risk mammograms into
density regions. As such, finer details are present in the
segmentations and more accurate measures of breast density
are produced. A set of high risk (BI-RADS IV) full field digital
mammograms with density annotations obtained from
radiologists are used to test the validity of the proposed
approach. By exploiting the manifold structure of the input
space, segmentations with average accuracy of 87% when
compared with radiologists’ segmentations can be obtained.
International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 9 143 – 147
_______________________________________________________________________________________________
145
IJRITCC | September 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
This is an increase of over 12% compared with segmentation in
the high-dimensional space.
In the paper [7], the authors used ICA mixture model.
In this work, we are proposing to use the technique called
Enhanced ICA Mixture Model (EICAMM) for automatic
segmentation of breast masses, aiming to comparing it to other
segmentation methods known for segmentation of medical
images such as Watershed, Self-Organizing Map (SOM), K-
means and Fuzzy C-means techniques. The segmentation rates
achieved in this paper 48.25% of pre-processes images and
51.75% for images without pre-processing.
The authors in the paper [8], used the k–means
thresholding. Breast skin–air interface and pectoral muscle
segmentation are usually first steps in all CAD applications on
scanned as well as digital mammograms. Breast skin–air
interface segmentation is much more difficult task when
performed on scanned mammograms than on digital
mammograms. In case of pectoral muscle segmentation,
segmentation difficulty of analog and digital mammograms is
usually similar. In this paper the authors present adaptive
contrast enhancement method for breast skin–air interface
detection which combines usage of adaptive histogram
equalization method on small region of interest which contains
actual edge and edge detection operators. Pectoral muscle
detection method uses combination of contrast enhancement
using adaptive histogram equalization and polynomial
curvature estimation on selected region of interest. This method
makes segmentation of very low contrast pectoral muscle areas
possible because of estimation used to segment areas which
have lower contrast difference than detection threshold. The
successful segmentation rate is 89.69%.
In this paper [9], the authors used Morphological
operations. The objective of this study is to examine an
algorithm of automated breast profile segmentation for
mammographic images. The main contribution of proposed
algorithm is applying the combined of thresholding technique
and morphological preprocessing to segregate background
region from the breast profile and remove radiopaque artifacts
and labels. To show the validity of our segmentation system, it
is extensively tested using over all mammographic images from
the MIAS database. The MIAS database comprises 322 images
with high intensity rectangular labels. Bright scanning
artifactswere found to be present in majority of the database
images. All square high intensity labels, apart from three were
removed at a rate of 99.06%. The qualitative assessment of
experimental results indicates that the method can accurately
segment the breast region in a large range of digitized
mammograms, covering all density classes.
The authors in the paper [10], Gradient based method
is used. Accurate segmentation of the breast from digital
mammograms is an important pre-processing step for
computerized breast cancer detection. In this study, we propose
a fully automated segmentation method. Noise on the acquired
mammogram is reduced by median filtering; multidirectional
scanning is then applied to the resultant image using a moving
window 15 1 in size. The border pixels are detected using the
intensity value and maximum gradient value of the window.
The breast boundary is identified from the detected pixels
filtered using an averaging filter. The segmentation accuracy on
a dataset of 84 mammograms from the MIAS database is 99%.
TABLE 1.Study on the different Techniques for detection of Breast Cancer
Author
Name
Title Methods Qualitative
Analysis of the paper
Chira
njiLalCho
wdhary,
D. P.
Acharjya
[1]
A Hybrid
Scheme for
Breast Cancer
Detection using
Intuitionistic
Fuzzy Rough
Set Technique
Intuitionis
tic Fuzzy Set,
Rough Set,
Indiscernibilit
y Relation,
Restricted
Equivalence
Function.
The classification
accuracy obtained by
the methods used in
this paper is 98.3%
Monic
a, Singh
Sanjay
Kumar,
AgrawalPr
ateek,
MadaanVi
shu [2]
Breast
Cancer
Diagnosis using
Digital Image
Segmentation
Techniques
Haar
Wavelet
Transform,
Binarization,
Segmentation,
Artificial
Neural
Network
The classification
accuracy has been
observed to the tune of
89% in this paper by
using the given
methods.
D.
Selvathi
and A.
AarthyPoo
rnila [3]
Breast
Cancer
Detection In
Mammogram
Images Using
Deep Learning
Technique
Unsupervi
sed Deep
Learning
The proposed
model has achieved an
accuracy of up to
98.5% in classifying
dense mammogram
images.
M.
Kanchana
and P.
Varalaksh
mi [4]
Breast
Cancer
Diagnosis
Using Wavelet
Based
Threshold
Method
Discrete
Wavelet
Transform,
Probabilistic
Neural
Network.
In this paper, the
proposed Computer
Aided Diagnosis
(CAD) system is tested
using Mammography
Image Analysis
Society (MIAS)
database and achieves
an accuracy of 92.3%.
Pin
Wang,
Xianlling
Hu,
Yongming
Li,
Qianqian
Liu and
Xinjian
Zhu [5]
Automatic
cell nuclei
segmentation
and
classification of
breast cancer
histopathology
images
Wavelet
decomposition
, multi-scale
region-
growing,
curvature scale
space,
adaptive
mathematical
morphology
In this paper, an
experimental results
show that the mean
segmentation
sensitivity was 91.53%
(74.05%) and
specificity was 91.64%
(74.07%). The
classification
performance of normal
and malignant cell
images can achieve
96.19% (70.31%) for
accuracy, 99.05%
(70.27%) for
sensitivity and 93.33%
(70.81%) for
specificity.
Harry
Strange
Manifold
Learning for
Manifold
Learning
In this paper, by
exploiting the manifold
International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 9 143 – 147
_______________________________________________________________________________________________
146
IJRITCC | September 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
et.al [6] Density
Segmentation in
High Risk
Mammograms
structure of the input
space, segmentations
with average accuracy
of 87% when
compared with
radiologists’
segmentations can be
obtained.
Patrici
a B et.al
[7]
Automatic
segmentation of
breast masses
using enhanced
ICA mixture
model
Independe
nt Component
Analysis
mixture model
The segmentation
rate achieved in this
paper 48.25% of pre-
processes images and
51.75% for images
without pre-processing
Mario
Mustr,
MislavGrg
ic [8]
Robust
automatic breast
and pectoral
muscle
segmentation
from scanned
mammograms
k–means
thresholding
This method
makes segmentation of
very low contrast
pectoral muscle areas
possible because of
estimation used to
segment areas which
have lower contrast
difference than
detection threshold.
The successful
segmentation rate is
89.69%.
Luqm
anMahood
Mina, Nor
Ashidhi
Mat Isa [9]
A Fully
Automated
Breast
Separation For
Mammographic
Images
Morpholo
gical
operations
In this paper, the
segmentation accuracy
is achieved as 99.06%
by using
Morphological
operations
Pelin
Kus,
IrfanKarag
oz [10]
Fully
automated
gradient based
breast boundary
detection for
digitized X-ray
mammograms
Gradient
based method
The segmentation
accuracy on a dataset
of 84 mammograms
from the MIAS
database is 99%
IV. COMPARATIVE STUDY ON THE PERFORMANCE
ANALYSIS ON THE RELATED WORKS DONE ON THE BREAST
CANCER DETECTION
In this section, the performance analysis is compared with
the various papers for the detection of breast cancer.
Figure 1. Performance analysis on the Accuracy of various reviewed paper.
From the above figure 1, the methods like Intuitionistic
Fuzzy set and Unsupervised Deep Learning methods gives the
maximum accuracy than the papers used segmentation,
Artificial Neural Network, Discrete Wavelet Transform and
Probabilistic Neural Network.
Figure 2.Performance analysis on the Segmentation Rate of various
reviewed paper
From the above figure 2, the x-axis represents the papers
reviewed and the y-axis depicts the segmentation rate in %. The
papers which use the morphological operations, Gradient based
method gives the better segmentation rate than the other
methods used in the papers.
V. CONCLUSION
This paper presented a survey and the comparative analysis
on the classical approaches of the image processing techniques
used in Digital Mammography. The techniques described in
papers include all the segmentation detection algorithms for
both single view and multi view mammograms and these
techniques suitable for breast region segmentation and ROI
segmentation.
REFERENCES
[1] Chiranji Lal Chowdhary, D. P. Acharjya, ―A Hybrid Scheme for
Breast Cancer Detection using Intuitionistic Fuzzy Rough Set
Technique‖, International Journal of Healthcare Information
Systems and Informatics, Volume 11, Issue 2, April-June 2016,
pp.38-43.
[2] Monica, Singh Sanjay Kumar, Agrawal Prateek, Madaan Vishu,
―Breast Cancer Diagnosis using Digital Image Segmentation
Techniques‖, Indian Journal of Science and Technology, Vol
9(28), July 2016, pp.1-5.
[3] D. Selvathi and A. Aarthy Poornila, ―Breast Cancer Detection In
Mammogram Images Using Deep Learning Technique‖,
Middle-East Journal of Scientific Research 25 (2): 417-426,
2017.
[4] M. Kanchana and P. Varalakshmi, ―Breast Cancer Diagnosis
Using Wavelet Based Threshold Method‖, Middle-East Journal
of Scientific Research 23 (6): 1030-1034, 2015.
[5] Pin Wang, Xianlling Hu, Yongming Li, Qianqian Liu and
Xinjian Zhu, ―Automatic cell nuclei segmentation and
classification of breast cancer histopathology images‖, Vol.122,
May 2015.
[6] Harry Strange, Erika Denton, Minnie Kibiro, and Reyer
Zwiggelaar, ―Manifold Learning for Density Segmentation in
International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169
Volume: 5 Issue: 9 143 – 147
_______________________________________________________________________________________________
147
IJRITCC | September 2017, Available @ http://www.ijritcc.org
_______________________________________________________________________________________
High Risk Mammograms‖, IbPRIA 2013, pp. 245–252, 2013,
Springer-Verlag Berlin Heidelberg 2013.
[7] Patricia B. Ribeiro, Roseli A.F. Romero, Patrícia R. Oliveira,
Homero Schiabel, Luciana B. Verçosa, ―Automatic
segmentation of breast masses using enhanced ICA mixture
model‖, Neurocomputing 120(2013) 61–71, Elsevier.
[8] Mario Mustr, Mislav Grgic, ―Robust automatic breast and
pectoral muscle segmentation from scanned mammograms‖,
Signal Processing 93 (2013) 2817–2827, Elsevier.
[9] Luqman Mahood Mina, Nor Ashidhi Mat Isa, ―A Fully
Automated Breast Separation For Mammographic Images‖,
IEEE International Conference on Bio Signal Analysis,
Processing and Systems ICBAPS, 2015, pp. 37-41.
[10] Pelin Kus, Irfan Karagoz, ―Fully automated gradient based
breast boundary detection for digitized X-ray mammograms‖,
Computers in Biology and Medicine 42 (2012) 75–82, Elsevier.

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A Comparative Study on the Methods Used for the Detection of Breast Cancer

  • 1. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 9 143 – 147 _______________________________________________________________________________________________ 143 IJRITCC | September 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ A Comparative Study on the Methods Used for the Detection of Breast Cancer Dr. T. Ramaprabha Professor, dept. of Computer Science, Vivekanandha College of arts and science for women (Autonomous), Namakkal, India. e-mail: ramaradha1971@gmail.com T. Sathya priya Asst.Professor, dept. of Computer Science, Shri Sakthikailash women's college, Salem, India e-mail: sathyapriyapoint@gmail.com Abstract—Among women in the world, the death caused by the Breast cancer has become the leading role. At an initial stage, the tumor in the breast is hard to detect. Manual attempt have proven to be time consuming and inefficient in many cases. Hence there is a need for efficient methods that diagnoses the cancerous cell without human involvement with high accuracy. Mammography is a special case of CT scan which adopts X-ray method with high resolution film. so that it can detect well the tumors in the breast. This paper describes the comparative study of the various data mining methods on the detection of the breast cancer by using image processing techniques. Keywords-Breast Cancer; Image Processing; Segmentation; Pre-Processing; Mammogram; Machine Learning. __________________________________________________*****_________________________________________________ I. INTRODUCTION The main cause of cancer death in women is due to Breast cancers. Early detection and diagnosis can be done through digital mammography which prevents the death rate increase all around the world. Early diagnosis prevents the unwanted growth of malignant cells which saves the life of the patients. The abnormalities in the breast are of various types such as masses, micro calcifications, speculated lesions and architectural distortions. These abnormalities occur in two types called begin and malignant. The beginning is non- cancerous abnormalities whereas the malignant abnormalities are reported as cancers by the radiologist. The breast masses normally occurs in the dense regions with different shapes, which includes shapes such as circumscribed, stellate, lobulated. They are difficult to detect because of the poor contrast, different sizes, shapes and the similarity to other breast muscles, blood vessels, fibrous tissues and breast parenchymal. The micro calcification occurs in clusters and they are tiny granules of calcium deposits which usually occur in the size range 0.1 mm to 0.7 mm with irregular shapes. The extraction of abnormalities from the digital mammograms is the main goal of image segmentation techniques. The segmentation methods consist of the breast regions segmentation and Regions of interest (ROI) segmentation. Segmenting the breast region, suppresses the background of the image and separates the breast regions for eliminating the surrounding areas which include the muscles, blood vessels, fibrous tissues and breast parenchymal. Segmentation of the regions of interest (ROI) is done by extracting the suspicious candidates which are targets of cancers by partitioning the image into non-overlapping regions of interest (ROI). Segmentation is done on single view mammograms and multi view mammograms. The single view mammogram segmentation consists of the supervised and unsupervised methods which includes region. The multi view mammogram segmentation works on the images of the left and right breasts, multiple views of the same breast and similar views taken at different time intervals. The entire segmentation process also includes the regions with false positives which are eliminated in the classification stages. II. BREAST CANCER DETECTION Early detection has been the rallying cry of breast cancer from the outset of the response to the disease. While exact causes of breast cancer are not known, evidence suggests that a combination of inherited and environmental causes must be present for it to develop. Efforts to prevent breast cancer are hampered by the disease’s complexity and the limits of our current scientific knowledge. Many established risk factors for breast cancer, including being a woman, aging, breast density, family history, genetics or a prior breast cancer diagnosis which cannot be modified. On the upside, evidence demonstrates that the risk of developing breast cancer can be reduced by maintaining a healthy body weight, being physically active, eating well and limiting alcohol consumption. However, because personal risk reduction is still no guarantee, early detection has been the ballast of hope and action for breast cancer. Until we are able to effectively prevent breast cancer, early detection will remain our leading strategy for reducing mortality and illness due to the disease. Early detection means using an approach that aims to diagnose breast
  • 2. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 9 143 – 147 _______________________________________________________________________________________________ 144 IJRITCC | September 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ cancer earlier than might otherwise occur. Breast cancer screening sometimes referred to as secondary prevention, is the routine testing of individuals without symptoms that aims to detect breast cancer at its earliest stages, so effective treatment can be offered. Since breast cancer screening began in Canada in the late 1980s, it is attributed with helping reduce breast cancer mortality by an estimated 25 - 30 percent. III. RELATED WORKS ON THE DETECTION OF BREAST CANCER BY USING DIFFERENT METHODS The following depicts the different Image Processing and Data Mining methods for the detection of breast cancer. The authors ChiranjiLalChowdhary, D. P. Acharjya in the paper [1], utilizes the Intuitionistic Fuzzy Set, Rough Set, Indiscernibility Relation, Restricted Equivalence Function methods for the detection of the breast cancer. In that paper, the hybrid scheme starts with image segmentation using intuitionistic fuzzy set to extract the zone of interest and then to enhance the edges surrounding it. The experimental analysis shows the overall accuracy of 98.3% and it is higher than the accuracy achieved by hybridizing fuzzy rough set model. In the paper [2], the authors Monica, Singh Sanjay Kumar, AgrawalPrateek, MadaanVishu, used the following methods Haar Wavelet Transform, Binarization, Segmentation, Artificial Neural Network. It is observed that the breast images are analyzed after decomposition. However, the image become smaller and crucial information may be lost by virtue of image decomposition and when region of interest is applied only on the specific segment of image as above said, some information get lost. Further, the high pass decomposed image using wavelet transform over enhance the intensity variation that may be falsely detected and cancer characteristics leading to erroneous analysis. These limitations could be overcome by denoising the given input image using the wavelet transform and analysis made on inverse transformed image. The texture features should also be considered while analyzing an image for cancer detection. A back propagation neural network is trained using the mammogram images in different categories and tested using the sample as well as unknown images 13 feature neurons are used for N/W training and testing as well. The N/W is trained for normal images as well as abnormal cases. The classification accuracy has been observed to the tune of 89%. D. Selvathi and A. AarthyPoornila in the paper [3] used Unsupervised Deep Learning method. The proposed system uses an unsupervised, deep learning based technique which uses Mammogram in the detection of breast cancer. The labeled data serves as the training set and the un-labeled images are classified with deep-learning nets. The deep network consists of stacked auto encoder and soft max classifier. The auto encoder has four hidden layers and a novel sparsityregularizer which incorporates both population sparsity and lifetime sparsity. The model is easy to apply and generalizes to many other scoring problems. The proposed model has achieved an accuracy of up to 98.5% in classifying dense mammogram images. M. Kanchana and P. Varalakshmi in the paper [4] used Discrete Wavelet Transform, Probabilistic Neural Network. In this paper initially, the mammography images are segmented using wavelet based threshold method. The proposed system provides valuable information to the radiologists and is helpful in detecting abnormalities faster than the traditional methods. The proposed Computer Aided Diagnosis (CAD) system is tested using Mammography Image Analysis Society (MIAS) database and achieves an accuracy of 92.3%. In this paper [5], the following methods are used by the authors, Wavelet decomposition, multi-scale region- growing, curvature scale space, adaptive mathematical morphology. In this paper, automatic quantitative image analysis technique of BCH images is proposed. For the nuclei segmentation, top bottom hat transform is applied to enhance image quality. Wavelet decomposition and multi-scale region growing (WDMR) are combined to obtain regions of interest (ROIs) there by realizing precise location. A double-strategy splitting model (DSSM) containing adaptive mathematical morphology and Curvature Scale Space (CSS) corner detection method is applied to split over lapped cells for better accuracy and robustness. For the classification of cell nuclei, 4 shape- based features and 138 textural features based on color spaces are extracted. Optimal feature set is obtained by support vector machine (SVM) with chain-like agent genetic algorithm (CAGA). The proposed method was tested on 68 BCH images containing more than 3600cells. Experimental results show that the mean segmentation sensitivity was 91.53% (74.05%) and specificity was 91.64% (74.07%). The classification performance of normal and malignant cell images can achieve 96.19% (70.31%) for accuracy, 99.05% (70.27%) for sensitivity and 93.33% (70.81%) for specificity. The authors Harry Strange in the paper [6], used Manifold Learning method. In this paper, the author said that there is a strong correlation between relative mammographic breast density and the risk of developing breast cancer. As such, accurately modeling the percentage of a mammogram that is dense is a pivotal step in density based risk classification. In this work, a novel method based on manifold learning is used to segment high-risk mammograms into density regions. As such, finer details are present in the segmentations and more accurate measures of breast density are produced. A set of high risk (BI-RADS IV) full field digital mammograms with density annotations obtained from radiologists are used to test the validity of the proposed approach. By exploiting the manifold structure of the input space, segmentations with average accuracy of 87% when compared with radiologists’ segmentations can be obtained.
  • 3. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 9 143 – 147 _______________________________________________________________________________________________ 145 IJRITCC | September 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ This is an increase of over 12% compared with segmentation in the high-dimensional space. In the paper [7], the authors used ICA mixture model. In this work, we are proposing to use the technique called Enhanced ICA Mixture Model (EICAMM) for automatic segmentation of breast masses, aiming to comparing it to other segmentation methods known for segmentation of medical images such as Watershed, Self-Organizing Map (SOM), K- means and Fuzzy C-means techniques. The segmentation rates achieved in this paper 48.25% of pre-processes images and 51.75% for images without pre-processing. The authors in the paper [8], used the k–means thresholding. Breast skin–air interface and pectoral muscle segmentation are usually first steps in all CAD applications on scanned as well as digital mammograms. Breast skin–air interface segmentation is much more difficult task when performed on scanned mammograms than on digital mammograms. In case of pectoral muscle segmentation, segmentation difficulty of analog and digital mammograms is usually similar. In this paper the authors present adaptive contrast enhancement method for breast skin–air interface detection which combines usage of adaptive histogram equalization method on small region of interest which contains actual edge and edge detection operators. Pectoral muscle detection method uses combination of contrast enhancement using adaptive histogram equalization and polynomial curvature estimation on selected region of interest. This method makes segmentation of very low contrast pectoral muscle areas possible because of estimation used to segment areas which have lower contrast difference than detection threshold. The successful segmentation rate is 89.69%. In this paper [9], the authors used Morphological operations. The objective of this study is to examine an algorithm of automated breast profile segmentation for mammographic images. The main contribution of proposed algorithm is applying the combined of thresholding technique and morphological preprocessing to segregate background region from the breast profile and remove radiopaque artifacts and labels. To show the validity of our segmentation system, it is extensively tested using over all mammographic images from the MIAS database. The MIAS database comprises 322 images with high intensity rectangular labels. Bright scanning artifactswere found to be present in majority of the database images. All square high intensity labels, apart from three were removed at a rate of 99.06%. The qualitative assessment of experimental results indicates that the method can accurately segment the breast region in a large range of digitized mammograms, covering all density classes. The authors in the paper [10], Gradient based method is used. Accurate segmentation of the breast from digital mammograms is an important pre-processing step for computerized breast cancer detection. In this study, we propose a fully automated segmentation method. Noise on the acquired mammogram is reduced by median filtering; multidirectional scanning is then applied to the resultant image using a moving window 15 1 in size. The border pixels are detected using the intensity value and maximum gradient value of the window. The breast boundary is identified from the detected pixels filtered using an averaging filter. The segmentation accuracy on a dataset of 84 mammograms from the MIAS database is 99%. TABLE 1.Study on the different Techniques for detection of Breast Cancer Author Name Title Methods Qualitative Analysis of the paper Chira njiLalCho wdhary, D. P. Acharjya [1] A Hybrid Scheme for Breast Cancer Detection using Intuitionistic Fuzzy Rough Set Technique Intuitionis tic Fuzzy Set, Rough Set, Indiscernibilit y Relation, Restricted Equivalence Function. The classification accuracy obtained by the methods used in this paper is 98.3% Monic a, Singh Sanjay Kumar, AgrawalPr ateek, MadaanVi shu [2] Breast Cancer Diagnosis using Digital Image Segmentation Techniques Haar Wavelet Transform, Binarization, Segmentation, Artificial Neural Network The classification accuracy has been observed to the tune of 89% in this paper by using the given methods. D. Selvathi and A. AarthyPoo rnila [3] Breast Cancer Detection In Mammogram Images Using Deep Learning Technique Unsupervi sed Deep Learning The proposed model has achieved an accuracy of up to 98.5% in classifying dense mammogram images. M. Kanchana and P. Varalaksh mi [4] Breast Cancer Diagnosis Using Wavelet Based Threshold Method Discrete Wavelet Transform, Probabilistic Neural Network. In this paper, the proposed Computer Aided Diagnosis (CAD) system is tested using Mammography Image Analysis Society (MIAS) database and achieves an accuracy of 92.3%. Pin Wang, Xianlling Hu, Yongming Li, Qianqian Liu and Xinjian Zhu [5] Automatic cell nuclei segmentation and classification of breast cancer histopathology images Wavelet decomposition , multi-scale region- growing, curvature scale space, adaptive mathematical morphology In this paper, an experimental results show that the mean segmentation sensitivity was 91.53% (74.05%) and specificity was 91.64% (74.07%). The classification performance of normal and malignant cell images can achieve 96.19% (70.31%) for accuracy, 99.05% (70.27%) for sensitivity and 93.33% (70.81%) for specificity. Harry Strange Manifold Learning for Manifold Learning In this paper, by exploiting the manifold
  • 4. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 9 143 – 147 _______________________________________________________________________________________________ 146 IJRITCC | September 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ et.al [6] Density Segmentation in High Risk Mammograms structure of the input space, segmentations with average accuracy of 87% when compared with radiologists’ segmentations can be obtained. Patrici a B et.al [7] Automatic segmentation of breast masses using enhanced ICA mixture model Independe nt Component Analysis mixture model The segmentation rate achieved in this paper 48.25% of pre- processes images and 51.75% for images without pre-processing Mario Mustr, MislavGrg ic [8] Robust automatic breast and pectoral muscle segmentation from scanned mammograms k–means thresholding This method makes segmentation of very low contrast pectoral muscle areas possible because of estimation used to segment areas which have lower contrast difference than detection threshold. The successful segmentation rate is 89.69%. Luqm anMahood Mina, Nor Ashidhi Mat Isa [9] A Fully Automated Breast Separation For Mammographic Images Morpholo gical operations In this paper, the segmentation accuracy is achieved as 99.06% by using Morphological operations Pelin Kus, IrfanKarag oz [10] Fully automated gradient based breast boundary detection for digitized X-ray mammograms Gradient based method The segmentation accuracy on a dataset of 84 mammograms from the MIAS database is 99% IV. COMPARATIVE STUDY ON THE PERFORMANCE ANALYSIS ON THE RELATED WORKS DONE ON THE BREAST CANCER DETECTION In this section, the performance analysis is compared with the various papers for the detection of breast cancer. Figure 1. Performance analysis on the Accuracy of various reviewed paper. From the above figure 1, the methods like Intuitionistic Fuzzy set and Unsupervised Deep Learning methods gives the maximum accuracy than the papers used segmentation, Artificial Neural Network, Discrete Wavelet Transform and Probabilistic Neural Network. Figure 2.Performance analysis on the Segmentation Rate of various reviewed paper From the above figure 2, the x-axis represents the papers reviewed and the y-axis depicts the segmentation rate in %. The papers which use the morphological operations, Gradient based method gives the better segmentation rate than the other methods used in the papers. V. CONCLUSION This paper presented a survey and the comparative analysis on the classical approaches of the image processing techniques used in Digital Mammography. The techniques described in papers include all the segmentation detection algorithms for both single view and multi view mammograms and these techniques suitable for breast region segmentation and ROI segmentation. REFERENCES [1] Chiranji Lal Chowdhary, D. P. Acharjya, ―A Hybrid Scheme for Breast Cancer Detection using Intuitionistic Fuzzy Rough Set Technique‖, International Journal of Healthcare Information Systems and Informatics, Volume 11, Issue 2, April-June 2016, pp.38-43. [2] Monica, Singh Sanjay Kumar, Agrawal Prateek, Madaan Vishu, ―Breast Cancer Diagnosis using Digital Image Segmentation Techniques‖, Indian Journal of Science and Technology, Vol 9(28), July 2016, pp.1-5. [3] D. Selvathi and A. Aarthy Poornila, ―Breast Cancer Detection In Mammogram Images Using Deep Learning Technique‖, Middle-East Journal of Scientific Research 25 (2): 417-426, 2017. [4] M. Kanchana and P. Varalakshmi, ―Breast Cancer Diagnosis Using Wavelet Based Threshold Method‖, Middle-East Journal of Scientific Research 23 (6): 1030-1034, 2015. [5] Pin Wang, Xianlling Hu, Yongming Li, Qianqian Liu and Xinjian Zhu, ―Automatic cell nuclei segmentation and classification of breast cancer histopathology images‖, Vol.122, May 2015. [6] Harry Strange, Erika Denton, Minnie Kibiro, and Reyer Zwiggelaar, ―Manifold Learning for Density Segmentation in
  • 5. International Journal on Recent and Innovation Trends in Computing and Communication ISSN: 2321-8169 Volume: 5 Issue: 9 143 – 147 _______________________________________________________________________________________________ 147 IJRITCC | September 2017, Available @ http://www.ijritcc.org _______________________________________________________________________________________ High Risk Mammograms‖, IbPRIA 2013, pp. 245–252, 2013, Springer-Verlag Berlin Heidelberg 2013. [7] Patricia B. Ribeiro, Roseli A.F. Romero, Patrícia R. Oliveira, Homero Schiabel, Luciana B. Verçosa, ―Automatic segmentation of breast masses using enhanced ICA mixture model‖, Neurocomputing 120(2013) 61–71, Elsevier. [8] Mario Mustr, Mislav Grgic, ―Robust automatic breast and pectoral muscle segmentation from scanned mammograms‖, Signal Processing 93 (2013) 2817–2827, Elsevier. [9] Luqman Mahood Mina, Nor Ashidhi Mat Isa, ―A Fully Automated Breast Separation For Mammographic Images‖, IEEE International Conference on Bio Signal Analysis, Processing and Systems ICBAPS, 2015, pp. 37-41. [10] Pelin Kus, Irfan Karagoz, ―Fully automated gradient based breast boundary detection for digitized X-ray mammograms‖, Computers in Biology and Medicine 42 (2012) 75–82, Elsevier.