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Presented by- Preeti Shukla
Lecture
RCN, Kanpur
Objectives-
At the end of the presentation student will able
to-
Define gestational diabetes mellitus
Enlist the causes of gestational diabetes mellitus.
Describe the investigation of gestational diabetes
mellitus.
List-down the effect of GDM in pregnancy and
fetus.
Explain the management of GDM.
Describe the prevention of GDM.
Gestational diabetes mellitus
• GDM is defined as carbohydrate intolerance or
glucose intolerence of variable severity with
onset of first recognition during present
pregnancy.
• Usually present late in second or during third
trimester.
• Gestational diabetes starts when the body is
unable to make all of the insulin it needs for
pregnancy.
• Low insulin levels, combined with hormonal
changes, can lead to insulin resistance. When
this happens, high levels of glucose build up in
the blood.
Causes-
• Positive family history of diabetes.
• Previous birth of overweight baby.
• Previous stillbirth with pancreatic islet
hyperplasia.
• Unexplained perinatal loss
• Presence of polyhydromnios
• Age over 30 year
• Obesity
Screening-
- Blood glucose test as soon as possible.
- Glucose tolerance test
GLUCOSE TOLERENCE TEST-
• A glucose screening test is a routine test during
pregnancy that checks a pregnant woman's blood
glucose (sugar) level.
• Gestational diabetes is high blood sugar
(diabetes) that starts or is found during
pregnancy.
• The person will have a fasting blood test, then
drink a glucose drink and have further blood tests
1, 2, and maybe 3 hours later.
• If blood sugar levels are high, and the person has
not had a diagnosis of diabetes before, the doctor
will probably diagnose gestational diabetes.
Effect of diabetes on pregnancy-
Maternal effect- (during pregnancy)-
• Abortion
• Preterm labour
• Infection (UTI, vulvo vaginitis)
• Increased incidence of preeclampsia.
• Polyhydramnios
• Maternal distress
• Diabetic retinopathy
• Diabetic nephropathy
• ketoacidosis
During labour-
• Prolongation of labour due to big baby.
• Shoulder dystocia
• Postpartum hemorrhage
• Operative interferences
During puerperium-
• Puerperal sepsis
• Lactation failure
Fetal and neonatal hazards:
• Fetal macrosomia
• Congenital malformation ( neural tube defects,
anencephaly, microcephaly, VSD, ASD,
coarctation of aorta, fallots tetrology, renal
agenesis, hydronephrosis, double ureter,
polycystic kidneys, duodenal atresia, anorectal
atresia, omphalocoele).
Management-
Principles-
• Careful antenatal supervision and glycemic
control, so as to maitain the glucose level near
to physiolgical level as possible.
• To find out the optimum time and method of
delivery.
• Arrangement for the care of the newborn.
• Pre conceptional counseling
• Antenatal care:-
Antenatal supervision should be at monthly
intervals up to 20 weeks and thereafter at 2
weeks intervals.
At times patient needs admission for
stabilization of blood glucose and for
monitoring the fetus.
 Diet- 30 kcal/kg for normal weight women,
24 kcal/kg for overweight women and 12
kcal/kg for morbidly obese women.
• Frequent blood sugar estimation is required as
the urine examination for sugar is not
informative.
• Monitoring of blood glucose by glucose meter
can give an accurate idea about the control.
• Examination of HbAIc level.
• Sonographic evaluation in pregnancy is
extremely helpful, not only to diagnose
varieties of congenital malformation of fetus
but also to detect fetal macrosomia or growth
restriction.
• Biophysical profile and NST should be
performed weekly.
• Insulin therapy- when diabetes is first detected
during pregnancy and cannot be controlled by
diet alone, it should be treated with insulin. A
post prandial plasma glucose level of 140
mg% even on diet control is an indication of
insulin therapy.
• during the stabilization process of the insulin
dose, frequent blood sugar estimation specially
at night (2am – 6am) may be necessary using
glucose meter.
• Induction of labour.
• Cesarean section
• Fetal monitoring during labour or after delivery-
during the labour process shoulder dystocia may
be a problem. The cord should be clamped
immediately after delivery to avoid hypervolemia.
• Examination of placenta and cord- placenta is
large, the cord is thick and there is increased
incidence of single umbilical artery.
• Puerperium care- antibiotics should be given,
insulin requirement falls dramatically following
delivery. breast feeding is encouraged . Women
who had breast feed should have additional
500kcal daily in diet. In lactating women insulin
dose is lower.
Prevention of GDM
Gestational Diabetes Presentation: Causes, Effects, Management
Gestational Diabetes Presentation: Causes, Effects, Management
Gestational Diabetes Presentation: Causes, Effects, Management
Gestational Diabetes Presentation: Causes, Effects, Management

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Gestational Diabetes Presentation: Causes, Effects, Management

  • 1. Presented by- Preeti Shukla Lecture RCN, Kanpur
  • 2. Objectives- At the end of the presentation student will able to- Define gestational diabetes mellitus Enlist the causes of gestational diabetes mellitus. Describe the investigation of gestational diabetes mellitus. List-down the effect of GDM in pregnancy and fetus. Explain the management of GDM. Describe the prevention of GDM.
  • 3.
  • 4. Gestational diabetes mellitus • GDM is defined as carbohydrate intolerance or glucose intolerence of variable severity with onset of first recognition during present pregnancy. • Usually present late in second or during third trimester.
  • 5. • Gestational diabetes starts when the body is unable to make all of the insulin it needs for pregnancy. • Low insulin levels, combined with hormonal changes, can lead to insulin resistance. When this happens, high levels of glucose build up in the blood.
  • 6. Causes- • Positive family history of diabetes. • Previous birth of overweight baby. • Previous stillbirth with pancreatic islet hyperplasia. • Unexplained perinatal loss • Presence of polyhydromnios • Age over 30 year • Obesity
  • 7. Screening- - Blood glucose test as soon as possible. - Glucose tolerance test
  • 8. GLUCOSE TOLERENCE TEST- • A glucose screening test is a routine test during pregnancy that checks a pregnant woman's blood glucose (sugar) level. • Gestational diabetes is high blood sugar (diabetes) that starts or is found during pregnancy. • The person will have a fasting blood test, then drink a glucose drink and have further blood tests 1, 2, and maybe 3 hours later. • If blood sugar levels are high, and the person has not had a diagnosis of diabetes before, the doctor will probably diagnose gestational diabetes.
  • 9.
  • 10. Effect of diabetes on pregnancy-
  • 11. Maternal effect- (during pregnancy)- • Abortion • Preterm labour • Infection (UTI, vulvo vaginitis) • Increased incidence of preeclampsia. • Polyhydramnios • Maternal distress • Diabetic retinopathy • Diabetic nephropathy • ketoacidosis
  • 12. During labour- • Prolongation of labour due to big baby. • Shoulder dystocia • Postpartum hemorrhage • Operative interferences During puerperium- • Puerperal sepsis • Lactation failure
  • 13. Fetal and neonatal hazards: • Fetal macrosomia • Congenital malformation ( neural tube defects, anencephaly, microcephaly, VSD, ASD, coarctation of aorta, fallots tetrology, renal agenesis, hydronephrosis, double ureter, polycystic kidneys, duodenal atresia, anorectal atresia, omphalocoele).
  • 14. Management- Principles- • Careful antenatal supervision and glycemic control, so as to maitain the glucose level near to physiolgical level as possible. • To find out the optimum time and method of delivery. • Arrangement for the care of the newborn.
  • 15. • Pre conceptional counseling • Antenatal care:- Antenatal supervision should be at monthly intervals up to 20 weeks and thereafter at 2 weeks intervals. At times patient needs admission for stabilization of blood glucose and for monitoring the fetus.  Diet- 30 kcal/kg for normal weight women, 24 kcal/kg for overweight women and 12 kcal/kg for morbidly obese women.
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  • 18. • Frequent blood sugar estimation is required as the urine examination for sugar is not informative. • Monitoring of blood glucose by glucose meter can give an accurate idea about the control. • Examination of HbAIc level. • Sonographic evaluation in pregnancy is extremely helpful, not only to diagnose varieties of congenital malformation of fetus but also to detect fetal macrosomia or growth restriction.
  • 19. • Biophysical profile and NST should be performed weekly. • Insulin therapy- when diabetes is first detected during pregnancy and cannot be controlled by diet alone, it should be treated with insulin. A post prandial plasma glucose level of 140 mg% even on diet control is an indication of insulin therapy. • during the stabilization process of the insulin dose, frequent blood sugar estimation specially at night (2am – 6am) may be necessary using glucose meter.
  • 20.
  • 21. • Induction of labour. • Cesarean section • Fetal monitoring during labour or after delivery- during the labour process shoulder dystocia may be a problem. The cord should be clamped immediately after delivery to avoid hypervolemia. • Examination of placenta and cord- placenta is large, the cord is thick and there is increased incidence of single umbilical artery. • Puerperium care- antibiotics should be given, insulin requirement falls dramatically following delivery. breast feeding is encouraged . Women who had breast feed should have additional 500kcal daily in diet. In lactating women insulin dose is lower.