2. INTRODUCTION
Prenatal diagnosis employs a variety of techniques
to determine the health and the condition of unborn
fetus . There are a variety of non invasive and
invasive techniques available for prenatal
diagnosis
3. INVASIVE METHOD
Amniocentesis
Chorionic villus sampling
Pregnancy associated plasma protein A (PAPP-A)
Maternal serum alpha –fetoprotein
Maternal serum beta-HCG
Maternal serum estradiol
Inhibin A
8. ULTRASONOGRAPHY
This is a non-invasive procedure that is harmless to
both the fetus and the mother. High frequency
sound waves are utilized to produce visible images
of the baby. The developing embryo can first be
visualized at about 6 weeks gestation.
9. Hard tissue gives bright white dots eg . Bone
Soft tissue gives – shades of gray
Fluid filled areas – no reflection i.e. black color.
10. PURPOSES:
To determine presence and location of pregnancy.
To detect multiple pregnancy
To identify need for follow up testing.
Confirming fetal viability.
Identify fetal abnormality.
Measurement of Crown Rump length of embryo.
11. Two methods:
Transvaginal ultrasonography
Trans abdominal ultrasonography
1. Trans vaginal ultrasonography
It is used during first trimester because the uterus,
gestational sac, embryo, ovaries and fallopian
tube are deep in to the pelvis in first trimester
13. Types of TAS
Doppler ultrasound
Color Doppler ultrasound.
1. Doppler ultrasound
it is to assess the blood flow. The wave is
directed at correct angle to a moving target as with
blood flowing through vessel and frequency of echoes
changes, as the cardiac cycle through systole and
diastole.
17. It is used for recording the fetal heart beat and the
uterine contraction during in pregnancy especially
in 3rd trimester
The machine used for monitoring is called
cardiotocograph and also called the electronic
fetal monitor
18. METHOD:
External measurements:
Two transducer are used externally by strapping to the
externally to the abdominal wall
One measure the fetal heart rate
Second transducer measure the uterine contraction
Internal measurements:
Requires certain degree of cervical dilatation. Pressure
catheter is inserted into the uterine cavity. Scalp electrode is
attached to the head of the fetus to measure the pulse
20. DEFINITION
It is a continuous electronic
fetal monitoring of FHR with
recording of fetal movement
in cardiotocography and
wellness of fetus.
21. PURPOSES
Assessment of fetal wellbeing.
To evaluate the ability of fetal heart rate
to accelerate
To know oxygen supply to fetus
To know the metabolic condition of fetus
24. INTERPRETATION
REACTIVE:
When 2 or more acceleration of
more 15 beats /min above the
baseline &longer than 15 sec in
duration are present in 20 mints
observation
25. NON REACTIVE
Less than 2 acceleration or acceleration that peak
at less than 15 bpm above the baseline and less
than 15 seconds at their base with or without fetal
movements
26. UNSATISFACTORY TEST
A tracing that cannot be
interpreted because of poor
quality of fetal heart tracing
NST needs to be repeated in 2-3
hours
27.
28. PROCEDURE
Mother placed in semi fowlers position to prevent
supine hypotension. Apply external electronic fetal
monitoring equipment to abdomen to detect FHR,
fetal movement and contraction.
30. CONTRACTION STRESS TEST
It is suggestive in NST findings are non
reactive. It involves the recording of
FHR, stress induced uterine contraction.
This test is done only during uterine
contraction.
31. PURPOSES
To find out the frequency, duration and
intensity of contraction.
To identify fetal heart rate and oxygen
supply to fetus.
To find out the fetal distress.
32. PROCEDURE
Make mother in semi fowlers, lateral position.
FHR and pattern must be evaluated in relation to
uterine contraction.
3 contractions of atleast 40 sec each and occurring
within 10 minutes period are required to interpret the
contraction.
34. Nipple stimulation method:
Advice the mother to brash palm across the nipple
through her clothing for 2 minutes. Stop if contraction
begins. It is repeated after 5 minutes rest period if no
contraction occur.
IV infusion of oxytocin:
If nipple stimulation does not result in adequate
contraction IV infusion of oxytocin is used to stimulate
the uterine contraction. Administration of oxytocin
similar to that for induction of Labor.
36. SUMMARIZATION
At the end of the teaching I summarized the topic
which include::
Introduction of the prenatal diagnosis
Invasive method
Ultrasonography
Cardiotocography
NST
CST
37. CONCLUSION
Invasive and non invasive prenatal diagnosis
most commonaly performed to assess the
embryo fetal chromosome and also gaining
the information about the embryo.
38. BIBLIOGRAPHY
Dutta Dc Textbook of obstetrics, ‘and gynecology 7th
edition , new central agency page no 235-236
Jacob Anamma , Textbook of obstetrics and gynecology
3rd edition Jaypee brother publisher145-146
Kamari Neelam , Textbook of obstetrics and gynecology
7th edition page no 237-238
Myles ,Textbook for Midwives ,15th edition CHURCHILL
living stone elsvier page no234-237