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THE CELL
UNIT 4 will cover cells . These topics are all related to one of the
         common characteristics of all living things.




 ALL LIVING THINGS ARE COMPOSED
             OF CELLS
What the heck is
a cell anyway?
It can also be considered as …
Finally it can be considered as…
Do you remember when we listed
    that one of the common
   characteristics of all living
 organisms was that they had a
         cellular nature?
      This means they were either
       composed of a singular cell
    (unicellular) or made up of many
           cells (multicellular)
Unicellular Organisms
(Living organisms made up from one cell.)
Multicellular organisms are
      composed of many cells.
(for example our stomach contains many cells of many different types.)
SO…How is the study of cells related to our
Ecological (Rivers ) Biology?   Your Ideas?
All cells are made from the big 4
     macromolecules of life.
       (Do you remember them?)
In some ways cells could be considered
       little ecosystems in that…
• They require energy.
• They cycle materials.
• They are interactions
  within different parts
  of the cell.
In this unit we will explore the
     cellular nature of life
by focusing on the similarities and differences
     between cells of different life forms.
Science in its historical perspective
                  First…a little history….
A long time ago, people believed in something called Spontaneous
Generation- since at least the time of Aristotle (4th Century BC),
people believed non-living objects can give rise to living organisms.
It was common “knowledge” that simple organisms like worms,
beetles, frogs, and salamanders could come from dust, mud, etc., and
food left out.




                   BUT THEY WERE WRONG!
Because they were wrong,
 we need a story to clarify
 and explain the truth.


 Once upon a time a long
 time ago…
 …the microscope was
 invented.

(mikros = small; skopo = observe)
HANS AND SON
Sometime about the year 1590,
two Dutch spectacle makers,
Zaccharias Janssen and his
father Hans started
experimenting with these
lenses. They put several
lenses in a tube and made a
very important discovery. The
object near the end of the tube
appeared to be, much larger
than any simple magnifying
glass! They had just invented
the compound microscope.
Galileo
     Galileo heard of their
     experiments and started
     experimenting on his
     own. He described the
     principles of lenses and
     light rays and improved
     both the microscope and
     telescope. He added a
     focusing device to his
     microscope and went on
     to explore the heavens
     with his telescopes.
Anton von Leeuwenhoek of Holland became very
  interested in lenses while working with magnifying
glasses in a dry goods store. He became so interested
  that he learned how to make rounded lenses which
produced greater magnification, and his microscopes
            were able to magnify up to 270X!
 Leeuwenhoek became more involved in science and
  with his new improved microscope was able to see
       things that no man had ever seen before.




  Anthony Leeuwenhoek (1632-1723) has since been
         called the "Father of Microscopy".
Then in 1665 English Scientist Robert Hooke used this new
                        microscope!
 Hooke discovered plant cells -- more precisely, what Hooke saw
were the cell walls in cork tissue. Hooke coined the term "cells":
  the boxlike cells of cork reminded him of the prayer cells in a
                             monastery.




 Robert Hooke's sketches of cork
             cells.
Check out the dates. While the microscope was rocking back in
1665, it was not until the early 1800’s that the idea of cells was put
together with its relationship to living things!
In 1809 Jean Baptiste Pierre Antoine de Monet Chevalier de
Lamarck, remarked that “No living thing can have life if its
parts are not made of cellular tissue or are not formed by
cellular tissue.”
 His theories were largely ignored or
 attacked; He never won the acceptance
 and esteem of his colleagues, and he
 died in poverty and obscurity
•   1838 Schleiden- observed that all plants seemed to be composed
    of cells
1839 Schwaan- extended Schleiden's cell theory to animals, stating
that all living things are composed of cells. Came up with the term
“CELL THEORY”
1858 Virchow- German pathologist Rudolf Virchow (1821 - 1902)
   altered the thought of cellular biology with his statement that
   "every cell comes from a cell“ a theory called BIOGENESIS

                 From their discoveries:
        THE CELL THEORY AROSE…
• THE CELL IS THE BASIC UNIT OF
               LIFE.
    • ALL LIVING THINGS ARE
       COMPOSED OF CELLS.
• ALL CELLS COME FROM OTHER
              CELLS.
PERSON             GETS
                  CREDITED
                   WITH:
Leeuwenhoek        Microscope

  Hooke       Found plant/cork cells and
               can up with term “cells”

  Lamarck      All life is made of cells

 Schwaan       Animals have cells
 Schleiden      Plants have cells
Cells Size
•Sizes on a microscope are measured in microns. A micron is one
millionth of a meter or 0.001 of a millimeter.
•They range in size
       Largest cell = Ostrich egg
       Smallest cell= .000001 microns Yikes-tiny!
       Average cell size= .5-40 microns
(remember 1 micron = .001 mm)
•Size is restricted: Why? Most cells are small has to do with
simple geometry more than anything else: specifically the
relationship between surface area to volume as a cell gets bigger.
The undisputed largest extant bird egg on earth today is laid by an
ostrich. An average egg weighs about three pounds (1.4 kg), and is
roughly equivalent to about two dozen chicken eggs. It would take
approximately 40 minutes to hard-boil an ostrich egg. The yolk of
 an ostrich egg is the largest cell by volume; however, nerve cells
from the spinal cord of a large hooved mammal may be nearly two
                          meters in length!
Highly magnified view (2000x) of          A culture of rod-shaped
human pus showing white blood cells      anthrax bacteria (Bacillus
(called neutrophils) with deeply-lobed    anthracis). Some of the
purple nuclei.                            bacteria have divided by
                                            fission (red arrow).
As the size of a cube
increases, the ratio of
the surface area to
volume gets smaller.
Why would this
surface area to
volume ratio impact
a cell?
Cells have an internal structure
• There are many different cells
• Obviously there is “stuff” inside them.
• Cells are classified into two groups
  depending on how that “stuff” is organized.
Cell organelles
• Some cells contain organelles.
• Consider that we have internal parts called
  organs.
• While some cells just have watery fluid
  with molecules inside them (prokaryotic
  cells,) others have well defined specialized
  parts called organelles (little organs.) These
  cells are called eukaryotic cells.
Types of cells
• PROKARYOTES               • EUKARYOTES
                             -MORE ADVANCED
  -UNICELLULAR
                             -ALL CELLS IN
  -ARE THE LARGEST           MULTICELLULAR
  GROUP OF ORGANISMS         ORGANISMS ARE
  -SIMPLE STRUCTURE          EUKARYOTES AND SOME
                             IN UNICELLULAR ORGAN.
  -NO NUCLEUS
                             - HAVE NUCLEUS
  -NO MEMBRANE BOUND         -THESE HAVE MEMBRANE
  ORGANELLES       -         BOUND ORGANELLES
  APPEARED ABOUT 4           -COMPLEX INTERNAL
  BILLION YEARS AGO- most    STRUCTURE
  primitive                  - APPEARED ABOUT 1
• EXAMPLE: bacteria          BILLION YEARS AGO

  & Blue green algae        EXAMPLE: fish, oak
                             trees, humans,
                             paramecium
PROKARYOTIC CELLS
No membrane bound                     Bacteria cells are very small-
nucleus. Instead, DNA is in           only a fraction of the size of an
a circular loop called a              animal cell.
plasmid!




Prokaryotes feature 3 major shapes:
spheres, rods, spirochetes.
PROKARYOTIC CELLS
            Bacteria serve as
            decomposers, act in
            the nitrogen cycle,
            are agents of
            fermentation, and
            play an important
            role in our own
            digestive system.
            But they can also
            make us SICK! 
.


     HOW THE EUKARYOTE
     FORMED FROM THIS FIRST
     BASIC PROKARYOTE…
Once upon a time (about one billion years ago), the first eukaryotic cell
came to be. There was a group of primitive bacteria going about their
business when along came a big hungry phagocyte, who ate one of the
bacterium.                                 Mr. Phagocyte: Yum.
                                             Bacterium: Excuse me.
                                             Mr. Phagocyte: What?
                                             Bacterium: You know, why don't
                                             we join forces and I can help you
                                             and you can help me and we can
                                             become a 'eukaryotic' cell?
                                             Whaddaya say?
                                             Mr. Phagocyte: OK
PROKARYOTE               EUKARYOTE




WITHOUT membrane bound   WITH membrane
organelles               bound organelles
PRO OR EUK
1.   Snake cells                  EUK
2.   Human cheek cells            EUK
3.   Venus fly trap plant cells   EUK
4.   Blue-green algae             PRO
5.   Fecal Coliform               PRO
6.   Salmon cells                 EUK
7.   Salmonella Bacterium cells   PRO
For now think of the cell as an independently functioning unit of life. In
 order to perform the many specific tasks there must be many specific
 parts. So we will come up with an ANALOGY- The Cell as the City.
THE CELL THE CITY
 •Cell membrane is like the _________________
                              City limits, borders
because it determines what comes in and of
                the cell/city
•The nucleus is like __________- a storage site
                        City hall
        for all the cells information.
                                Land, air, and water
•The cytoplasm is like the __________________
in the city. They are the substances in the
cell that carry oxygen, proteins, carbs, and
              other substances.
  •The mitochondria is like a _____________.
                                Power plant
 This is where nutrients are converted into
           usable cellular energy.
•Ribosomes are the site where protein is put
    together. Like the __________ of a city.
                        factories
•Endoplasmic reticulum are like ___________________________
                                         Business district
because they are where the proteins, lipids, and carbohydrates (3 of
the big 4) are processed




•Golgi apparatus are like the _____________________. They are
                                Post office/UPS/FedEx
the parts that modify and package up the cellular materials before
being excreted out of the cell.
•Lysosomes and peroxisomes are the _______________________.
                                   Waste removal/sewage plant
They store strong digestive enzymes (proteins.)




                                          Lysosomes under the
Like a stack of pancakes                  microscope
•Chloroplasts are analogous to ________________________ found in
                                      a solar Power plant
green plant cells and some protists. They convert sunlight into
cellular or (chemical) energy.




 •Vacuoles are like the city’s water Supply/warehousesThey hold water
                               _________________.
 and nutrients for the cell. Large central vacuoles usually just found
 in plant cells
                             traffic patterns within the
 •Centrioles are like the __________________________ which aid
                                         cell
 in cell/movement and division. Found mainly in animal cells.
Cell wall is analogous to ________________________________.
                           an outside city surrounding highway
It is found mainly in plants/fungi and provides support to the cell.




                         Chemical storage/refineries
Vesicles are like _____________________________ which hold
food and energy molecules for chemical reactions, similar to
vacuoles.


    Cell analogy Project: Can you come up with a creative
        analogy for cell organelles in a eukaryotic cell?
A little review…
 What cell parts are primarily found in
             PLANT cells?
  CELL WALLS, CHLOROPLASTS AND LARGE
          CENTRAL VACUOLES

What cell parts are primarily present in
            ANIMAL cells?
              CENTRIOLES
More review
LET’S FILL IN THE CHART BELOW WITH 1 WORD
ANSWERS.

   CELL PART           ONE WORD
                       FUNCTION
   CELL
   MEMBRANCE
   GOLGI BODIES
   VACUOLES
                                            Click for
   NUCLEUS                                  answers

   LYSOSOME
POSSIBLE CHART ANSWERS
   CELL PART     ONE WORD
                 FUNCTION
     CELL         regulator
  MEMBRANCE
  GOLGI BODIES    packager
   VACUOLES        storage
    NUCLEUS      information
   LYSOSOME       digestion
Let’s look at some cells
CELL MOVEMENT
                 Plant cells
                          need to
                        move from
Cells need to move. Why? Turn to your
                        one plant to
                       another- like
table partner and come up with 3 types
                         pollen- so
                         that it too
  of cells and why they might need to
                        can fertilize
                          another
                 move?    plant for
                       reproduction
                           White blood cells
                                           need to move
Sperm cells need to                     around the body to
“swim to the egg” to                         help fight
                                             infection!
    fertilize it!
How do cells move?
   PLANT CELLS CAN NOT MOVE ON
  THEIR OWN…THEY RELY ON THEIR
      ENVIRONMENT TO MOVE…
 EXAMPLES: air, wind, water moving
 cells from one place to another.
  JUST ANOTHER REASON WHY WE
  NEED TO KEEP OUR RIVERS CLEAN
          AND FLOWING!
Some animal cells rely on bodily fluids to
         move them as well.
Animal cells move
•Cilia= many small hair like
structures around the
outside of the cell


•Flagella- long whip-like
extensions from cell.
Propeller-like.


Pseudopod- false foot
extension of cell membrane
LET’S EXPLORE
          REAL CELLS
What might a cell look like under a microscope?


           Will we see all the parts?




What might we see more often in plants than in
                 animals?
Let’s have a look!

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All Living Things Are Composed of Cells

  • 1. THE CELL UNIT 4 will cover cells . These topics are all related to one of the common characteristics of all living things. ALL LIVING THINGS ARE COMPOSED OF CELLS
  • 2. What the heck is a cell anyway?
  • 3. It can also be considered as …
  • 4. Finally it can be considered as…
  • 5. Do you remember when we listed that one of the common characteristics of all living organisms was that they had a cellular nature? This means they were either composed of a singular cell (unicellular) or made up of many cells (multicellular)
  • 6. Unicellular Organisms (Living organisms made up from one cell.)
  • 7. Multicellular organisms are composed of many cells. (for example our stomach contains many cells of many different types.)
  • 8. SO…How is the study of cells related to our Ecological (Rivers ) Biology? Your Ideas?
  • 9. All cells are made from the big 4 macromolecules of life. (Do you remember them?)
  • 10. In some ways cells could be considered little ecosystems in that… • They require energy. • They cycle materials. • They are interactions within different parts of the cell.
  • 11. In this unit we will explore the cellular nature of life by focusing on the similarities and differences between cells of different life forms.
  • 12. Science in its historical perspective First…a little history…. A long time ago, people believed in something called Spontaneous Generation- since at least the time of Aristotle (4th Century BC), people believed non-living objects can give rise to living organisms. It was common “knowledge” that simple organisms like worms, beetles, frogs, and salamanders could come from dust, mud, etc., and food left out. BUT THEY WERE WRONG!
  • 13. Because they were wrong, we need a story to clarify and explain the truth. Once upon a time a long time ago… …the microscope was invented. (mikros = small; skopo = observe)
  • 14. HANS AND SON Sometime about the year 1590, two Dutch spectacle makers, Zaccharias Janssen and his father Hans started experimenting with these lenses. They put several lenses in a tube and made a very important discovery. The object near the end of the tube appeared to be, much larger than any simple magnifying glass! They had just invented the compound microscope.
  • 15. Galileo Galileo heard of their experiments and started experimenting on his own. He described the principles of lenses and light rays and improved both the microscope and telescope. He added a focusing device to his microscope and went on to explore the heavens with his telescopes.
  • 16. Anton von Leeuwenhoek of Holland became very interested in lenses while working with magnifying glasses in a dry goods store. He became so interested that he learned how to make rounded lenses which produced greater magnification, and his microscopes were able to magnify up to 270X! Leeuwenhoek became more involved in science and with his new improved microscope was able to see things that no man had ever seen before. Anthony Leeuwenhoek (1632-1723) has since been called the "Father of Microscopy".
  • 17.
  • 18. Then in 1665 English Scientist Robert Hooke used this new microscope! Hooke discovered plant cells -- more precisely, what Hooke saw were the cell walls in cork tissue. Hooke coined the term "cells": the boxlike cells of cork reminded him of the prayer cells in a monastery. Robert Hooke's sketches of cork cells.
  • 19. Check out the dates. While the microscope was rocking back in 1665, it was not until the early 1800’s that the idea of cells was put together with its relationship to living things! In 1809 Jean Baptiste Pierre Antoine de Monet Chevalier de Lamarck, remarked that “No living thing can have life if its parts are not made of cellular tissue or are not formed by cellular tissue.” His theories were largely ignored or attacked; He never won the acceptance and esteem of his colleagues, and he died in poverty and obscurity
  • 20. 1838 Schleiden- observed that all plants seemed to be composed of cells 1839 Schwaan- extended Schleiden's cell theory to animals, stating that all living things are composed of cells. Came up with the term “CELL THEORY” 1858 Virchow- German pathologist Rudolf Virchow (1821 - 1902) altered the thought of cellular biology with his statement that "every cell comes from a cell“ a theory called BIOGENESIS From their discoveries: THE CELL THEORY AROSE…
  • 21. • THE CELL IS THE BASIC UNIT OF LIFE. • ALL LIVING THINGS ARE COMPOSED OF CELLS. • ALL CELLS COME FROM OTHER CELLS.
  • 22. PERSON GETS CREDITED WITH: Leeuwenhoek Microscope Hooke Found plant/cork cells and can up with term “cells” Lamarck All life is made of cells Schwaan Animals have cells Schleiden Plants have cells
  • 23. Cells Size •Sizes on a microscope are measured in microns. A micron is one millionth of a meter or 0.001 of a millimeter. •They range in size Largest cell = Ostrich egg Smallest cell= .000001 microns Yikes-tiny! Average cell size= .5-40 microns (remember 1 micron = .001 mm) •Size is restricted: Why? Most cells are small has to do with simple geometry more than anything else: specifically the relationship between surface area to volume as a cell gets bigger.
  • 24. The undisputed largest extant bird egg on earth today is laid by an ostrich. An average egg weighs about three pounds (1.4 kg), and is roughly equivalent to about two dozen chicken eggs. It would take approximately 40 minutes to hard-boil an ostrich egg. The yolk of an ostrich egg is the largest cell by volume; however, nerve cells from the spinal cord of a large hooved mammal may be nearly two meters in length!
  • 25. Highly magnified view (2000x) of A culture of rod-shaped human pus showing white blood cells anthrax bacteria (Bacillus (called neutrophils) with deeply-lobed anthracis). Some of the purple nuclei. bacteria have divided by fission (red arrow).
  • 26. As the size of a cube increases, the ratio of the surface area to volume gets smaller. Why would this surface area to volume ratio impact a cell?
  • 27. Cells have an internal structure • There are many different cells • Obviously there is “stuff” inside them. • Cells are classified into two groups depending on how that “stuff” is organized.
  • 28. Cell organelles • Some cells contain organelles. • Consider that we have internal parts called organs. • While some cells just have watery fluid with molecules inside them (prokaryotic cells,) others have well defined specialized parts called organelles (little organs.) These cells are called eukaryotic cells.
  • 29. Types of cells • PROKARYOTES • EUKARYOTES -MORE ADVANCED -UNICELLULAR -ALL CELLS IN -ARE THE LARGEST MULTICELLULAR GROUP OF ORGANISMS ORGANISMS ARE -SIMPLE STRUCTURE EUKARYOTES AND SOME IN UNICELLULAR ORGAN. -NO NUCLEUS - HAVE NUCLEUS -NO MEMBRANE BOUND -THESE HAVE MEMBRANE ORGANELLES - BOUND ORGANELLES APPEARED ABOUT 4 -COMPLEX INTERNAL BILLION YEARS AGO- most STRUCTURE primitive - APPEARED ABOUT 1 • EXAMPLE: bacteria BILLION YEARS AGO & Blue green algae EXAMPLE: fish, oak trees, humans, paramecium
  • 30. PROKARYOTIC CELLS No membrane bound Bacteria cells are very small- nucleus. Instead, DNA is in only a fraction of the size of an a circular loop called a animal cell. plasmid! Prokaryotes feature 3 major shapes: spheres, rods, spirochetes.
  • 31. PROKARYOTIC CELLS Bacteria serve as decomposers, act in the nitrogen cycle, are agents of fermentation, and play an important role in our own digestive system. But they can also make us SICK! 
  • 32. . HOW THE EUKARYOTE FORMED FROM THIS FIRST BASIC PROKARYOTE… Once upon a time (about one billion years ago), the first eukaryotic cell came to be. There was a group of primitive bacteria going about their business when along came a big hungry phagocyte, who ate one of the bacterium. Mr. Phagocyte: Yum. Bacterium: Excuse me. Mr. Phagocyte: What? Bacterium: You know, why don't we join forces and I can help you and you can help me and we can become a 'eukaryotic' cell? Whaddaya say? Mr. Phagocyte: OK
  • 33. PROKARYOTE EUKARYOTE WITHOUT membrane bound WITH membrane organelles bound organelles
  • 34. PRO OR EUK 1. Snake cells EUK 2. Human cheek cells EUK 3. Venus fly trap plant cells EUK 4. Blue-green algae PRO 5. Fecal Coliform PRO 6. Salmon cells EUK 7. Salmonella Bacterium cells PRO
  • 35. For now think of the cell as an independently functioning unit of life. In order to perform the many specific tasks there must be many specific parts. So we will come up with an ANALOGY- The Cell as the City.
  • 36. THE CELL THE CITY •Cell membrane is like the _________________ City limits, borders because it determines what comes in and of the cell/city •The nucleus is like __________- a storage site City hall for all the cells information. Land, air, and water •The cytoplasm is like the __________________ in the city. They are the substances in the cell that carry oxygen, proteins, carbs, and other substances. •The mitochondria is like a _____________. Power plant This is where nutrients are converted into usable cellular energy. •Ribosomes are the site where protein is put together. Like the __________ of a city. factories
  • 37. •Endoplasmic reticulum are like ___________________________ Business district because they are where the proteins, lipids, and carbohydrates (3 of the big 4) are processed •Golgi apparatus are like the _____________________. They are Post office/UPS/FedEx the parts that modify and package up the cellular materials before being excreted out of the cell. •Lysosomes and peroxisomes are the _______________________. Waste removal/sewage plant They store strong digestive enzymes (proteins.) Lysosomes under the Like a stack of pancakes microscope
  • 38. •Chloroplasts are analogous to ________________________ found in a solar Power plant green plant cells and some protists. They convert sunlight into cellular or (chemical) energy. •Vacuoles are like the city’s water Supply/warehousesThey hold water _________________. and nutrients for the cell. Large central vacuoles usually just found in plant cells traffic patterns within the •Centrioles are like the __________________________ which aid cell in cell/movement and division. Found mainly in animal cells.
  • 39. Cell wall is analogous to ________________________________. an outside city surrounding highway It is found mainly in plants/fungi and provides support to the cell. Chemical storage/refineries Vesicles are like _____________________________ which hold food and energy molecules for chemical reactions, similar to vacuoles. Cell analogy Project: Can you come up with a creative analogy for cell organelles in a eukaryotic cell?
  • 40. A little review… What cell parts are primarily found in PLANT cells? CELL WALLS, CHLOROPLASTS AND LARGE CENTRAL VACUOLES What cell parts are primarily present in ANIMAL cells? CENTRIOLES
  • 41. More review LET’S FILL IN THE CHART BELOW WITH 1 WORD ANSWERS. CELL PART ONE WORD FUNCTION CELL MEMBRANCE GOLGI BODIES VACUOLES Click for NUCLEUS answers LYSOSOME
  • 42. POSSIBLE CHART ANSWERS CELL PART ONE WORD FUNCTION CELL regulator MEMBRANCE GOLGI BODIES packager VACUOLES storage NUCLEUS information LYSOSOME digestion
  • 43. Let’s look at some cells
  • 44.
  • 45.
  • 46.
  • 47. CELL MOVEMENT Plant cells need to move from Cells need to move. Why? Turn to your one plant to another- like table partner and come up with 3 types pollen- so that it too of cells and why they might need to can fertilize another move? plant for reproduction White blood cells need to move Sperm cells need to around the body to “swim to the egg” to help fight infection! fertilize it!
  • 48. How do cells move? PLANT CELLS CAN NOT MOVE ON THEIR OWN…THEY RELY ON THEIR ENVIRONMENT TO MOVE… EXAMPLES: air, wind, water moving cells from one place to another. JUST ANOTHER REASON WHY WE NEED TO KEEP OUR RIVERS CLEAN AND FLOWING! Some animal cells rely on bodily fluids to move them as well.
  • 49. Animal cells move •Cilia= many small hair like structures around the outside of the cell •Flagella- long whip-like extensions from cell. Propeller-like. Pseudopod- false foot extension of cell membrane
  • 50. LET’S EXPLORE REAL CELLS What might a cell look like under a microscope? Will we see all the parts? What might we see more often in plants than in animals?
  • 51. Let’s have a look!