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Chromosomes and Mitosis
Chapter 1 Thompson and Thompson
1 Chromosomal Basis of Heredity
• A gene is a unit
of heredity
• Genes are
carried on DNA
• DNA is
contained
within
chromosomes as
chromatin
Chromosomes replicate during cell
division
The chromosome
complement
Chromosome analysis
Cri Du Chat results
from loss of a small
piece of chromosome
5
Gene Map
Chromosome
pairs
Non-identical genes
Sex
chromosomes
• These determine the sex of an
individual
– Two X chromosomes make a female
– One X and one Y a male
Two types of Cell Division
• Cells divide for two reasons
– To create genetically identical
copies of themselves
• This is
mitosis
– To create gametes that
contain half of the
chromosomes of the original
cell
• This is meiosis
46
46 46
46
23 23 23 23
The Cell
Cycle
S phase
Replication
Condensation
Schematic
DNA replication
Duplex DNA begins Replicating
Replication bubbles merge creating two duplexes
Mitosis
The stages of Mitosis
Prophase Detail
Prometaphase
Metaphase
Anaphase
Telophase
The sum total of
the process
Karyotypes
Chromosome
Length
Chromosome appearance

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chromosomal basis of heredity