D-Discuss the hypervitaminosis D

1. MED_STUDENTS0

2. OBJECTIVES :
 D-Discuss the hypervitaminosis D
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4.  Hypervitaminosis D :
 is a state of vitamin D toxicity.
 is a rare
 Excess amounts of vitamin D can cause abnormally high
levels of calcium in the blood, which can affect bones,
tissues, and other organs.
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5. SYMPTOMS OF VITAMIN D TOXICITY
 Excessive amounts of vitamin D in the body can cause calcium
levels in the blood to rise. This can lead to a condition called
hypercalcemia which can cause a variety of symptoms, including:
 high blood pressure
 heart arrhythmias
 ringing in the ear (tinnitus)
 excessive urination
 Dehydration
 abnormal heart rhythms
 Constipation

6.  Possible Complications:
 Dehydration
 Hypercalcemia
 Kidney damage
 Kidney stones
 Excessive bone loss

7. CAUSES OF VITAMIN D TOXICITY
 Vitamin D toxicity is usually caused by megadoses of
vitamin D supplements — not by diet or sun exposure.
That's because your body regulates the amount of
vitamin D produced by sun exposure.
 health problems such as:
 kidney disease, liver disease

8. HOW VITAMIN D TOXICITY IS DIAGNOSED
 blood tests to check vitamin D levels,
(used to determine if kidney damage is present)
 25-hydroxy vitamin D test(; Calcidiol; 25-hydroxycholecalciferol test):
The normal range is 30.0 to 74.0 nanograms per milliliter (ng/mL).
This test is done to determine if you have too much or too little vitamin D
in your blood.
 Serum calcium
 Serum phosphorus
 urine tests to check for excessive amounts
of calcium in the urine.
 bone X-rays to determine if significant
bone loss has occurred.
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9.  stop taking vitamin D supplements immediately.
 a low calcium diet
 generous intake of fluids
 vitamin D levels must be frequently monitored until
they return to normal.
 Some drugs to decrease amount of Vitamin D:
 corticosteroids , bisphosphonates.
Treatment for Vitamin D Toxicity
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10. HOW MUCH VITAMIN D DO YOU NEED?
 According to the Office of
Dietary Supplements, the amount of
vitamin D you require varies with age :
 Babies up to 12 months old require 400 IU,

11. SUMMARY
 vitamin D toxicity is uncommon even among people who
take supplements, you may be at greater risk if you have
health problems, such as liver or kidney conditions,
 Possible Complications
 Kidney damage
 Kidney stones
 Excessive bone lose
Diagnosis :
 25-hydroxy vitamin D test (30-74)
 Serum calcium
 Serum phosphorus
 urine tests
 bone X-rays.

12. Questions ?
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