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PERIOPERATIVE
MANAGEMENT
MANIRABONA E. MD, PGY-2 General Surgery
SCOPE
• Introduction
• History Taking and Physical Examination
• Investigation
• High Risk Patient
• Perioperative medical optimization
• Take Home Message
• References
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
2
Introduction
• Every surgical procedure involves some risk of significant
postoperative complications or death
• Early identification and optimal care of the high-risk surgical
patient will result in a substantial reduction of the risk.
• Operative mortality is more meaningfully expressed in terms of
deaths occurring during surgery and up to 30 days after surgery.
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
3
History Taking
• Do not assume that history has
been adequately covered
previously
• Important points may have
been overlooked in a busy OPD
• Standard history focuses on
the patient’s hopes and
expectations
Principles of history taking
• Listen: What is the problem?
(Open questions)
• Clarify: What does the patient
expect? (Closed questions)
• Narrow: Differential diagnosis
(Focused questions)
• Fitness: Comorbidities (Fixed
questions)
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
4
Past Medical History
CARDIOVASCULAR
• Ischemic heart disease
• Myocardial infarction
• Hypertension or HF
• Peripheral vascular disease
• Deep vein thrombosis and PE
RESPIRATORY
• COPD and Asthma
• Respiratory infections
GIT
• PUD and GERD
• Liver disease
GUT
• UTI ,RF and Prostatism
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
5
Past Medical History
Endocrine and metabolic
• Diabetes
• Thyroid dysfunction
• Phaeochromocytoma
Previous surgery
• Problems encountered
• Family history of problems
with anaesthesia
Other
• Human immunodeficiency
virus
• Malignancy
• Allergy
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
6
Physical Examination
General
• Anaemia, Jaundice, Cyanosis,
Nutritional status
• Infection source (teeth, feet, leg
ulcers)
CVS
• Pulse, BP, heart sounds
• Peripheral oedema
Respiratory
• RR and effort, chest expansion
• Percussion note breath sounds
and oxygen saturation
GIT
• Abdominal masses, ascites,
bowel sounds
• Hernia and genitalia
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
7
INVESTIGATIONS
FBC
• Major operations in elderly
and in those with anemia
• Pathology with ongoing
blood los
Low risk of bleeding: No
tests required.
Urea and electrolytes
• Major operation and >60
years old patient
• Cardiovascular, renal and
endocrine disease
• Anticipated blood loss
• Medication : NSAID,
diuretics, steroids
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
8
INVESTIGATIONS
ECG
• Patients aged over 60 years
• Cardiovascular, renal and DM
β-Human chorionic
gonadotrophin
• Pregnancy needs to be ruled
out in all women of childbearing
age.
CXR
• Cardiac failure and smokers
• COPD and Acute respiratory
symptoms
Blood glucose and HbA1c
• DM or family history
• Obese or poor nutrition
• Steroid use
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
9
Factors that predispose patients to a
high risk of morbidity and mortality
Patient factors
• History of severe cardiac disease (IHD, MI, cardiac Failure)
• Severe respiratory disease (COPD, respiratory failure)
• Aged >70 years with limited physiological reserve in vital organs
• Metabolic disease (renal failure, poorly controlled diabetes)
• Morbid obesity or Poor nutrition
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
10
Surgical factors
• Prolonged duration of surgery (>1.5 hours)
• Extensive surgery (e.g. esophagectomy, gastrectomy)
• Type of surgery (thoracic, abdominal, vascular)
• Emergency surgery or Acute massive blood loss (>2.5 liters)
• Septicemia (positive blood cultures or septic focus)
• Multiple trauma e.g. >3 organs or >2 systems or 2 body cavities
open
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
11
Perioperative care factors
• Inadequate critical care facilities
• Insufficient patient monitoring
• Lack of early intervention as complications develop
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
12
Identification of high risk Patient
Risk scoring systems have been developed over the years
with the aim of identifying high-risk patients
• ASA is simple, but subject to user interpretation
• MET measures exercise tolerance related to daily living
• RCRI used to predict cardiac risk for non-cardiac surgery
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
13
ASA grade Operative mortality
risk prediction
• American Society of
Anesthesiologists scoring
system is widely used
• It is simple and related to
operative mortality
• It does not take into account
age or nature of surgery and
it is operator dependent
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
14
Metabolic equivalent of task
• 1 MET = eating and dressing
• 4 MET = climbing two flights of stairs
• 6 MET = short run
• >10 MET = able to participate in
strenuous sport
Patient with ≥4 METS have lower risk of
perioperative mortality
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
15
The revised cardiac risk index of
Lee Thomas
• Goldman cardiac risk index
and the revised cardiac risk
index (RCRI) of Lee
• Designed to predict cardiac
morbidity
• May also be used to stratify
the risk of mortality
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
16
Management of pre-existing
medical conditions
• Coexisting disease processes should be reviewed and optimized
• Action taken include stopping smoking, reducing alcohol intake,
losing weight, improving nutrition and/or hemoglobin levels
• AAA surgery repair may require complex investigations like carotid
duplex scans. If the scans reveal a significant blockage, carotid
endarterectomy is done prior to AAA repair to reduce stroke risk
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
17
Minimizing myocardial ischaemia
• Anesthesia should avoid tachycardia, hypertension and
hypotension
• Pain control is important
• Oxygen supplementation is advisable for 3–4 days postoperatively
• Perioperative b-blockade should be considered
• Elective postoperative critical care admission should be
considered
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
18
Optimizing perioperative
respiratory function
• Preoperative pulmonary function needs testing to assess
functional status
• Consider bronchodilator ± steroid therapy
• Arrange pre- and postoperative chest physiotherapy and
breathing exercises
• Consider regional anesthesia
• Give good quality pain relief
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
19
DM Patient optimization
• Patients with diet-controlled diabetes require no special
preoperative treatment
• Patients on oral hypoglycaemics or subcutaneous insulin should
stop therapy the night before surgery and put on a glucose and
insulin infusion
• Long-acting insulin should be avoided the night before major
surgery
• Patients with diabetes should be placed first on the operating list
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
20
Patient with Bleeding disorders
or on anticoagulation
• These Patients sometimes need hematologist consultation
• Hemophilic disorder patients require replacement with specific
clothing factors
• Patients on warfarin should be converted to heparin
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
21
Medication to STOP
• NSAIDS - anti-platelet effect, discontinued before surgery 5-7 days.
• Clopidogrel – stopped 7 days prior to surgery due to bleeding risk.
• Hypoglycaemics –
• Oral contraceptive pill (OCP) or Hormone Replacement Therapy
(HRT) – stopped 4 weeks before surgery due to DVT risk and PE
• Warfarin – usually stopped 5 days prior to surgery due to bleeding
risk and commenced on therapeutic dose LMWH
o INR < 1.5 or warfarinisation with Vitamin K
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
22
Antibiotic Prophylaxis
• SSI occurs at or near surgical incision within 30 days of the procedure or
within one year if an implant is left in place
• Prophylactic antibiotics should be initiated within 1h before surgical incision
or two hours if the patient is receiving vancomycin or fluoroquinolones
• Patients should receive prophylactic antibiotics appropriate for their specific
procedure
• Prophylactic antibiotics is discontinued 24 hours of surgery completion
(within 48 hours for cardiothoracic surgery)
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
23
Prophylactic Antibiotics
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
24
Take Home Message
• Postoperative complications and deaths after surgery occur in the
high-risk patient
• Mortality results ultimately either from a cardiac event or
multiorgan dysfunction and poor tissue oxygenation
• Identification of high risk patient and perioperative management is
essential to prevent post-operative complications
• Multidisciplinary team approach is crucial to successful
management.
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
25
References
1. Bailey And Love's Short Practice of Surgery 25th and 26th editions
2. Am Fam Physician 2011;83(5):585-590 Copyright © 2011 American Academy
of Family Physicians.)
3. Schwartz's Principles of Surgery, 10th edition
4. SABISTON TEXTBOOK of SURGERY, 20th edition , The BIOLOGICAL BASIS of
MODERN SURGICAL PRACTICE
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery
26
THANK YOU
Comments, Inputs and
Suggestions
welcome
Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery27

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Perioperative Management Optimization

  • 2. SCOPE • Introduction • History Taking and Physical Examination • Investigation • High Risk Patient • Perioperative medical optimization • Take Home Message • References Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 2
  • 3. Introduction • Every surgical procedure involves some risk of significant postoperative complications or death • Early identification and optimal care of the high-risk surgical patient will result in a substantial reduction of the risk. • Operative mortality is more meaningfully expressed in terms of deaths occurring during surgery and up to 30 days after surgery. Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 3
  • 4. History Taking • Do not assume that history has been adequately covered previously • Important points may have been overlooked in a busy OPD • Standard history focuses on the patient’s hopes and expectations Principles of history taking • Listen: What is the problem? (Open questions) • Clarify: What does the patient expect? (Closed questions) • Narrow: Differential diagnosis (Focused questions) • Fitness: Comorbidities (Fixed questions) Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 4
  • 5. Past Medical History CARDIOVASCULAR • Ischemic heart disease • Myocardial infarction • Hypertension or HF • Peripheral vascular disease • Deep vein thrombosis and PE RESPIRATORY • COPD and Asthma • Respiratory infections GIT • PUD and GERD • Liver disease GUT • UTI ,RF and Prostatism Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 5
  • 6. Past Medical History Endocrine and metabolic • Diabetes • Thyroid dysfunction • Phaeochromocytoma Previous surgery • Problems encountered • Family history of problems with anaesthesia Other • Human immunodeficiency virus • Malignancy • Allergy Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 6
  • 7. Physical Examination General • Anaemia, Jaundice, Cyanosis, Nutritional status • Infection source (teeth, feet, leg ulcers) CVS • Pulse, BP, heart sounds • Peripheral oedema Respiratory • RR and effort, chest expansion • Percussion note breath sounds and oxygen saturation GIT • Abdominal masses, ascites, bowel sounds • Hernia and genitalia Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 7
  • 8. INVESTIGATIONS FBC • Major operations in elderly and in those with anemia • Pathology with ongoing blood los Low risk of bleeding: No tests required. Urea and electrolytes • Major operation and >60 years old patient • Cardiovascular, renal and endocrine disease • Anticipated blood loss • Medication : NSAID, diuretics, steroids Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 8
  • 9. INVESTIGATIONS ECG • Patients aged over 60 years • Cardiovascular, renal and DM β-Human chorionic gonadotrophin • Pregnancy needs to be ruled out in all women of childbearing age. CXR • Cardiac failure and smokers • COPD and Acute respiratory symptoms Blood glucose and HbA1c • DM or family history • Obese or poor nutrition • Steroid use Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 9
  • 10. Factors that predispose patients to a high risk of morbidity and mortality Patient factors • History of severe cardiac disease (IHD, MI, cardiac Failure) • Severe respiratory disease (COPD, respiratory failure) • Aged >70 years with limited physiological reserve in vital organs • Metabolic disease (renal failure, poorly controlled diabetes) • Morbid obesity or Poor nutrition Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 10
  • 11. Surgical factors • Prolonged duration of surgery (>1.5 hours) • Extensive surgery (e.g. esophagectomy, gastrectomy) • Type of surgery (thoracic, abdominal, vascular) • Emergency surgery or Acute massive blood loss (>2.5 liters) • Septicemia (positive blood cultures or septic focus) • Multiple trauma e.g. >3 organs or >2 systems or 2 body cavities open Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 11
  • 12. Perioperative care factors • Inadequate critical care facilities • Insufficient patient monitoring • Lack of early intervention as complications develop Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 12
  • 13. Identification of high risk Patient Risk scoring systems have been developed over the years with the aim of identifying high-risk patients • ASA is simple, but subject to user interpretation • MET measures exercise tolerance related to daily living • RCRI used to predict cardiac risk for non-cardiac surgery Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 13
  • 14. ASA grade Operative mortality risk prediction • American Society of Anesthesiologists scoring system is widely used • It is simple and related to operative mortality • It does not take into account age or nature of surgery and it is operator dependent Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 14
  • 15. Metabolic equivalent of task • 1 MET = eating and dressing • 4 MET = climbing two flights of stairs • 6 MET = short run • >10 MET = able to participate in strenuous sport Patient with ≥4 METS have lower risk of perioperative mortality Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 15
  • 16. The revised cardiac risk index of Lee Thomas • Goldman cardiac risk index and the revised cardiac risk index (RCRI) of Lee • Designed to predict cardiac morbidity • May also be used to stratify the risk of mortality Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 16
  • 17. Management of pre-existing medical conditions • Coexisting disease processes should be reviewed and optimized • Action taken include stopping smoking, reducing alcohol intake, losing weight, improving nutrition and/or hemoglobin levels • AAA surgery repair may require complex investigations like carotid duplex scans. If the scans reveal a significant blockage, carotid endarterectomy is done prior to AAA repair to reduce stroke risk Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 17
  • 18. Minimizing myocardial ischaemia • Anesthesia should avoid tachycardia, hypertension and hypotension • Pain control is important • Oxygen supplementation is advisable for 3–4 days postoperatively • Perioperative b-blockade should be considered • Elective postoperative critical care admission should be considered Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 18
  • 19. Optimizing perioperative respiratory function • Preoperative pulmonary function needs testing to assess functional status • Consider bronchodilator ± steroid therapy • Arrange pre- and postoperative chest physiotherapy and breathing exercises • Consider regional anesthesia • Give good quality pain relief Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 19
  • 20. DM Patient optimization • Patients with diet-controlled diabetes require no special preoperative treatment • Patients on oral hypoglycaemics or subcutaneous insulin should stop therapy the night before surgery and put on a glucose and insulin infusion • Long-acting insulin should be avoided the night before major surgery • Patients with diabetes should be placed first on the operating list Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 20
  • 21. Patient with Bleeding disorders or on anticoagulation • These Patients sometimes need hematologist consultation • Hemophilic disorder patients require replacement with specific clothing factors • Patients on warfarin should be converted to heparin Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 21
  • 22. Medication to STOP • NSAIDS - anti-platelet effect, discontinued before surgery 5-7 days. • Clopidogrel – stopped 7 days prior to surgery due to bleeding risk. • Hypoglycaemics – • Oral contraceptive pill (OCP) or Hormone Replacement Therapy (HRT) – stopped 4 weeks before surgery due to DVT risk and PE • Warfarin – usually stopped 5 days prior to surgery due to bleeding risk and commenced on therapeutic dose LMWH o INR < 1.5 or warfarinisation with Vitamin K Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 22
  • 23. Antibiotic Prophylaxis • SSI occurs at or near surgical incision within 30 days of the procedure or within one year if an implant is left in place • Prophylactic antibiotics should be initiated within 1h before surgical incision or two hours if the patient is receiving vancomycin or fluoroquinolones • Patients should receive prophylactic antibiotics appropriate for their specific procedure • Prophylactic antibiotics is discontinued 24 hours of surgery completion (within 48 hours for cardiothoracic surgery) Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 23
  • 24. Prophylactic Antibiotics Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 24
  • 25. Take Home Message • Postoperative complications and deaths after surgery occur in the high-risk patient • Mortality results ultimately either from a cardiac event or multiorgan dysfunction and poor tissue oxygenation • Identification of high risk patient and perioperative management is essential to prevent post-operative complications • Multidisciplinary team approach is crucial to successful management. Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 25
  • 26. References 1. Bailey And Love's Short Practice of Surgery 25th and 26th editions 2. Am Fam Physician 2011;83(5):585-590 Copyright © 2011 American Academy of Family Physicians.) 3. Schwartz's Principles of Surgery, 10th edition 4. SABISTON TEXTBOOK of SURGERY, 20th edition , The BIOLOGICAL BASIS of MODERN SURGICAL PRACTICE Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery 26
  • 27. THANK YOU Comments, Inputs and Suggestions welcome Perioperative Management by Dr MANIRABONA Emmanuel, MD, PGY 2 General Surgery27