1. •Cardiovascular diseases
•Smoking-related atheroclerosis

2.  A class of diseases that involve the heart,
blood vessels or both.
 Multi-factorial
 Leading cause of deaths in the world

3.  In greek, ‘athere’ means gruel and ‘skleros’
means hard
 Usually called arteriosclerosis, ‘arteria’
translates to artery and therefore,
arteriosclerosis is the hardening of the
arteries.

4.  Atherosclerosis is a type of arteriosclerosis
that affects only the inner lining of an artery.
 It is characterized by plaque deposits that
block the flow of blood.

5.  a response to damage to the endothelium
from high cholesterol, high blood pressure, and
cigarette smoking
Physicians may be able to make a diagnosis
of
atherosclerosis during a physical exam by
means of
a stethoscope and gentle probing of the
arteries with the hand (palpation).

6.  Atherosclerosis develops over years. It
happens through a complicated process of
cholesterol plaque formation that involves:
 Damaged endothelium.
 Cholesterol invasion.
 Plaque formation.

7.  It is one of the supposed causes
 Smoking greatly aggravates and speeds up
the growth of atherosclerosis in the coronary
arteries, the aorta and the arteries of the
legs.

8.  Control blood pressure
 Quit smoking
 Cholesterol diet
 Loose weight, if necessary
 Exercise
 Lipid-lowering drugs
 Bypass surgery
http://www.youtube.com/watch?v=qRK7-
DCDKEA