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7. infarction; hemodynamic disorders

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7. infarction; hemodynamic disorders

  1. 1. Hemodynamic Disorders Edema Hyperemia and Congestion Hemorrhage Hemostasis and Thrombosis Embolism Infarction Shock 1 Dr. Krishna Tadepalli, MD, www.mletips.com
  2. 2. Infarction Infarction  Definition = ischemic necrosis of tissue due to occlusion  Definition = ischemic necrosis of tissue due to occlusion of arterial ((in most of cases) or venous ((in gonads) of arterial in most of cases) or venous in gonads) circulation circulation  Most common cause of Death in USA  Most common cause of Death in USA  Most commonly  in 99% of cases = arterial occlusion  Most commonly  in 99% of cases = arterial occlusion by thrombo-embolism by thrombo-embolism  Rarely  venous drainage problem ((in Testis, Ovary)  Rarely  venous drainage problem in Testis, Ovary)  Very rarely  vasospasm  Very rarely  vasospasm  Morphological Types  Red & White  Morphological Types  Red & White  Wedge shaped with base at the periphery of organ  Wedge shaped with base at the periphery of organ  Final outcome Coagulative necrosis ((Liquefactive in  Final outcome Coagulative necrosis Liquefactive in Brain) Brain)  Septic infarction = in pts. With infective Endocarditis  Septic infarction = in pts. With infective Endocarditis 2 Dr. Krishna Tadepalli, MD, www.mletips.com
  3. 3. Infarctions- Types Red (Hemorrhagic) White (Anemic) Red (Hemorrhagic) White (Anemic)  Venous occlusion  Venous occlusion  In loose tissues  In loose tissues (lung) (lung)  Organs with dual  Organs with dual blood supply (Lungs, blood supply (Lungs, Liver) Liver)  Previously congested  Previously congested organs organs ((nutmeg liver) nutmeg liver)  Re- perfused tissues  Re- perfused tissues • Arterial occlusion • Arterial occlusion • Solid organs • Solid organs • End arterial supply • End arterial supply ((Kidney, Spleen, Kidney, Spleen, Retina, Heart) Retina, Heart) 3 Dr. Krishna Tadepalli, MD, www.mletips.com
  4. 4. Infarction Red & White 4 Dr. Krishna Tadepalli, MD, www.mletips.com
  5. 5.  Final outcome of Infarction in heart  Final outcome of Infarction in heart How old is it ( after the onset of MI)? 5 Dr. Krishna Tadepalli, MD, www.mletips.com
  6. 6.  Final outcome of Infarction in heart  Final outcome of Infarction in heart How old is it ( after the onset of MI)? 5 Dr. Krishna Tadepalli, MD, www.mletips.com

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