microbiology List and explain the five characteristics of the adaptive immune response. What occurs if the adaptive immune response mistakenly recognizes a protein made by the body as foreign instead of self. Why does lymph flow through lymph nodes before it is returned to the blood? Explain the relationship between plasma, interstitial fluid and lymph. Explain the differences between antigen presentation involving MHC I and MHC II. (There are three major differences.) Trace the path of antigen processing for exogenous pathogens and endogenous pathogens. List the five classes of antibody and explain the major differences between the classes. .