Your Guide to Recombinant human hyaluronidase ph20.

1. 2019/3/13 Recombinant Human Hyaluronidase PH20
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Description
Recombinant Human Hyaluronidase PH20 belongs to a family of
enzymes that catalyze the degradation of hyaluronic acid (HA). The
enzyme is effective to hyaluronic acid in the extracellular matrix
(ECM) and promote the diffusion of extracellular substances.
Product Information
Cat No. NATE-1923
EC No. EC 3.2.1.35
CAS No. 37326-33-3
Species: Human
Source: CHO
Purity: ≥99%
Activity: ≥12,000 IU/vial
Endotoxin: ≤10 EU/ml
Storage: -20 °C
Control Tests: Laboratory of QC
Appearance: Sterile lyophilized powder,
dissolved in pure water to form a clear,
colorless to pale yellow solution. Must not
contain visible insoluble matter.
Highlights
Creative Enzymes® Hyaluronidase PH20 shows several advantages over similar products on the
market:
Creative Enzymes® HAase PH20 Similar Products on the Market
Species Human Animal
Source CHO cell Testis
Technology Recombinant DNA Extraction
Purity ≥99% Low
Applications
Oncology
PH20 degrades HA in tumor cells
coating, which may result in the
inhibition of tumor cell growth.
Enzymatic degradation of ECM HA with
PH20 is associated with remodeling of
the tumor stroma, reduction of tumor
interstitial fluid pressure, and expansion
of tumor blood vessels, resulting in
facilitated delivery of anti-cancer
agents.
Pharmacokinetics
PH20 hydrolyzes hyaluronic acid and
increases diffusion of injected drugs, thus
facilitating their absorption.
PH20 can be used as an adjunct in
subcutaneous urography to improve
resorption of radiopaque agents.
Scientific Research
ELISA; SDS-PAGE; Western blot.
Note: Our products are not intended for private therapeutic use!
Tel: 1-631-562-8517
Fax: 1-631-938-8127
E-mail: info@creative-enzymes.com
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA
Contact Information