Curriculum Vitae

1. Address: 48A K1 Extn Mohan Garden Uttam Nagar,
New Delhi -110059, India
Phone: +91-9560584896
Email: kamaljain84@gmail.com
Dr. Kamal Jain, Ph.D.
Research, Analytics and Scientific Professional
Biological Science/Pharmaceuticals/Healthcare
SUMMARY
 Self-motivated, creative, idea-driven, detail-oriented research and analytics professional with 8+ years of
experience working with two of the India's most renowned research institutions, Jawahar Lal Nehru
University (New Delhi) and CSIR-Institute of Microbial technology (Chandigarh)
 Excellent ability to device and perform primary and secondary research, analyze data, prepare
reports and present the outcomes to a variety of audience while meeting strict deadlines
 Strong experience in life sciences, healthcare and biopharmaceutics domains
 Educated from top-tier universities: Jawahar Lal Nehru University (New Delhi) and IMTech Chandigarh
 Managed projects working independently as well as in teams comprising members from around the
nation
 Contributed in preparation of Database using data mining from different sources
 Published research work in two peer-reviewed international journals
RELEVANT SKILLS AND COURSES
 Data analysis tools: MS Excel, Origin and SigmaPlot
 Databases: NCBI (Pubmed, Pubchem, ChemBank, GeneBank), Google Scholar, Scirus, BRENDA (Enzyme
databank) and RCSB Protein Data Bank, ZINC, KEGG Pathway
 Other software tools: MS (Word, PowerPoint and Outlook), Endnote and Adobe Photoshop, AutoDock,
ICM, Pymol, Origin, Swiss-PDB, R, Endnote, Web development (basic knowledge)
 Courses: Introduction to Entrepreneuership, Intellectual Property Rights and Practices (IMTech,
Chandigarh), Management, Biostatistics, Computational Biology and Bioinformatics (JNU, New Delhi)
 Operating Systems: Linux, Windows, Chrome
EXPERIENCE
 Postdoctoral research fellow, GGSIP University New Delhi (India) 2014-2015
 Secondary Research: Conducted literature search on molecular structures of RNA pol II
subunits, preparation of graphs for the growth pattern of yeast and their similarities with
humans
 Primary Research: Conducted lab research on the changes in the growth pattern of yeast on
mutating different proteins along with expression and purification of protein using recombinant
DNA technology and analyzed the data using linear/non-linear regression analysis
 Presentation Skills: Presented findings from literature search and lab research in intra-
departmental lab meetings; actively involved in departmental journal club and presented
several recent research papers
 Writing Skills: One manuscript under preparation
 Predoctoral research fellow, Institute of Microbial Technology Chandigarh (India), 2008-2016
 Secondary Research: Conducted literature search on drug molecules regulating the activity of
epigenetic proteins involved in various disease in humans and biophysical properties of these
proteins
 Primary Research: Conducted lab research on the enzymes involved in type 2 diabetes, cancer and
aging along-with data mining for preparation of a database on epigenetic modulators and analyzed
the experimental data using linear/non-linear regression analysis
 Presentation Skills: Presented findings from literature search and lab research in various
meetings, seminars and conferences
 Writing Skills: One manuscript published and one under revision

2. Master’s student at Jawahar Lal Nehru University, New Delhi (India), 2008
 Literature search for association of SIRT1 promoter region with Type 2 Diabetes
 Contributed in identifying association of Single Nucleotide Polymorphism in SIRT1 promoter region with
Type 2 Diabetes prevalence in North Indian population (Published)
EDUCATION
 PhD (Life Science), Institute of Microbial Technology, Chandigarh (India), 2008-2016
 MSc (Life Science), Jawahar Lal Nehru University, New Delhi (India), 2006-2008
 BSc (Biology, Chemistry), University of Bikaner, Bikaner (India), 2003-2006
PUBLICATIONS
 Rai E, Sharma S, Kaul S, Jain K, Matharoo K, Bhanwer AS, Bamezai RN 2012. The interactive effect of SIRT1
promoter region polymorphism on type 2 diabetes susceptibility in the North Indian population.. PLoS One.
7(11):e48621
 Loharch S, Bhutani I, Jain K, Sahoo DK, Gupta P, Parkesh R 2015. EpiDBase: a manually curated database
for small molecule modulators of Epigenetic Landscape.. Database Vol. 2015: article ID bav013;
doi:10.1093/database/bav013
 Jain K; Pandey K; Rathore YS; Sahoo DK; Ashish. Full Length SIRT1-
Coenzyme/Substrate/Activator/Inhibitor Complex is a Loosely Assembled Trimer in Solution: SAXS Data
Based Structural Model (Manuscript under revision).
HONORS AND AWARDS
 Extended Senior Research Fellowship in Life Sciences, 2014-2015
Council of Scientific and Industrial Research, Gov. of India
 Senior Research Fellowship in Life Sciences, 2010-2013
University Grants Commission, Gov. of India
 Junior Research Fellowship in Life Sciences, 2008-2010
University Grants Commission, Gov. of India
 National Eligibility Test (NET) in Life Sciences, 2008
Council of Scientific and Industrial Research, Gov. of India
 Graduate Aptitude Test (GATE) in Biotechnology, 2008
Indian Institute of Technology, Kanpur, India
 Fellowship, 2006-2008
University Grants Commission, Gov. of India
 Merit scholarship, 2003-2006
University of Bikaner, Bikaner, India
Leadership and Co-Curricular acrivities
 Organizer, 2008
Spandan (Annual Fest of School of Life Science, JNU, New Delhi)
 Event Coordinator, 2007
Spandan (Annual Fest of School of Life Science, JNU, New Delhi)
 Volunteer, 2003-2006
National Service Scheme, SDPG College, Sri Ganganagar
 Won multiple debate and speech competitions
PERSONAL INFORMATION
 Date of birth: 12 November, 1984
 Interests: Rock and Jazz music, travekking, bikes, electronics
 Languages: English (Fluent), Hindi (Mother tongue)

3. RESEACRH EXPERIENCE AND INTEREST
My research interest lies in the structural and biochemical characterizations of challenging proteins
such as multi-subunit complexes and mammalian proteins. I have followed my interest since last eight years
and have gained sufficient experience in this area. During my research career I have developed skills of
working independently as well as in team, making hypotheses, designing experiments, analyzing data,
writing grant application and papers and presenting research work to a variety of audience in form of posters
and oral presentations.
I worked as Extended Senior Research Fellow from December 2014 to December 2015 in the lab of
Dr. Nimisha Sharma (GGS Indraprastha University, New Delhi, India). The lab works on elucidating molecular
mechanism of transcription regulation in yeast by studying the biochemical and biophysical properties of
different RNA polymerase subunits. My project was based on deciphering the biochemical and biophysical
properties of yeast ELL and EAF proteins. I worked on expression and purification optimization of
recombinant ELL and EAF. Manuscript on this work is currently in progress.
Before joining Dr. Nimisha’s lab, I was a doctoral student in Dr. Debandra K. Sahoo’s lab in CSIR-
Institute of Microbial Technology (Chandigarh, India) from August 2008 till December 2014. The lab works
on multiple domains ranging from nanoparticle to structural studies of proteins. My doctoral work focused
on the structural and functional characterizations of the human SIRT1 protein and screening of activity
modulators of SIRT1 using computational and in vitro screening.
SIRT1 is a large tri-domain protein with a conserved central catalytic domain. The protein remains
conserved from archae to humans. However, its size varies considerably among the organism due to flanking
N- and C-terminal domains, with SIRT1 being the largest. Regulation of its activity has been found to play a
critical role in controlling multiple disease like type 2 diabetes, cancer, senescence. I performed structural
studies on SIRT1 using Small Angle X-ray scattering and computational modelling to decipher the global
shape of protein in solution. This data was then used for screening of various nutraceutical libraries for the
activity modulation of the protein. A manuscript on the above studies is under communication.
Simultaneously, I also assisted Dr. Raman Parkesh with the creation of EpiDbase: a database for the
epigenetic modulators, by helping in the development of website and searching the available literature for
various reported modulators. This work has been published in the Database journal in 2015.
I have also an opportunity to workwith human genetics under the supervision of Prof. R.N.K. Bamezai
at Jawahar Lal Nehru University. This work has been published in Plos One journal in 2013.