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CURRICULUM VITAE
ANUJ THAKUR
(B.Sc, M. Sc, Ph.D.)
Correspondence Address
B-185 B, Lajpat Nagar,
Sahibabad, Ghaziabad,
U.P – 201005
Email: anujt13@gmail.com
Mobile: +91-9911754636
Career Objective
 To reach such a challenging and rewarding position as a Researcher and educator that demands me to
apply my entire intellectuality and to retain my identity in the society by achieving the summit of
perfection in my duties and responsibilities
Current Position
 Research Associate at Mankind Pharma, one of the fastest growing pharmaceutical companies of
India. Job profile includes :-
 Designing the synthetic route and executing the multistep organic synthesis of impurities
associated with active pharmaceutical ingredient (API)
 Literature search for designing synthetic route using Scifinder.
 Characterization of products via their Analytical data (NMR, Mass, HPLC, IR etc.).
Doctorate Details
 Thesis entitled “Design, Facile Synthesis and Development of Novel Molecular Hybrids as
Therapeutic Agents” has been submitted on 15/7/2015 and defended on 19/1/16.
Supervisor and Affiliation
Name: Diwan S. Rawat
Designation: Professor (Full)
Department: Department of Chemistry
Institution: University of Delhi, Delhi, India
Research Work
 Design and synthesis of novel heterocyclic anti-cancer, anti-malarial and anti-Parkinsonian compounds
based on the recently introduced concept of molecular hybridization.
 Synthesized library of quinoline-pyrimidine hybrids and piperidone based C5-curcuminoids through
multi-step synthesis.
 Designed and synthesized novel organo-catalytic systems for catalyzing various organic
transformations of synthetic importance, including MCRs.
 Reactions like Claisen–Schmidt condensation, knoevenagel condensation, sonogashira coupling,
various nucleophilic substitution reactions, reduction etc were performed at different stages of course.
 In-silico studies of most active compounds were performed using Schrodinger Maestro software
Awards & Fellowship
 At present availing Senior Research Fellowship from Council of Scientific and Educational Research,
India since January 2013.
 Received Junior Research Fellowship from Council of Scientific and Educational Research, India from
January 2011 to December 2012.
 Qualified JOINT CSIR-UGC TEST FOR JUNIOR RESEARCH FELLOWSHIP (JRF)
ANDNATIONAL ELIGIBILITY FOR LECTURESHIP (NET) in Chemical Sciences, June 2010
Academic Qualifications
Degree/Examination University/Board Period % Marks
Ph.D. (Chemistry)
Dept. of Chemistry,
University of Delhi Jan-2011 to Jan-2016 -
M.Sc.
(Organic Chemistry)
Dept. of Chemistry,
University of Delhi 2008-2010 62.81
B.Sc.Gen (Group A) Zakir Hussain College,
University Of Delhi
2004-2007 66.14
10+2 CBSE 2004 72.8
10th
ICSE 2002 72.5
Professional Skills
 Good knowledge of synthetic organic chemistry, excellent laboratory skills and synthetic route
designing skills with a strong capacity to conduct independent research.
 Proficient in handling reactions from mg to gram scale and in purifying the crude product through
column chromatography
 Instrument handling like IR, UV, Microwave
 Proficient in characterizing compounds through spectroscopic techniques
 Skilled in scientific content writing
 Working knowledge of Microsoft Word, Excel, Power-Point
 Proficient in software packages like ChemDraw, Delta, Origin.
 Basic knowledge of Schrodinger Maestro (QSAR and docking)
Research Publications
1. A. Thakur, M. Tripathi, U. Chinna. Rajesh and D. S. Rawat “Ethylenediammonium-diformate
(EDDF) in PEG600: An efficient ambiphilic novel catalytic system for the one-pot synthesis of 4H-
pyrans via Knoevenagel condensation” RSC Adv., 2013, 3, 18142- 18148.
2. A. Thakur, S. I. Khan and D. S. Rawat “Synthesis of piperazine tethered 4-aminoquinoline-pyrimidine
hybrids as potent antimalarial agents” RSC Adv., 2014, 4, 20729-20736.
3. A. Thakur, S. Manohar, C. E. V. Gerena, B. Zayas, V. Kumar, S. V. Malhotra and D. S. Rawat “Novel
3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity
evaluation and mode of action study” Med. Chem. Commun., 2014, 5, 576-586.
4. S. Manohar, A.Thakur, S. I. Khan, G. Sun, N. Ni, B. Wang and D. S. Rawat “Synthesis of
Unsymmetrical C5-Curcuminoids as Potential Anticancer Agents” Lett. Drug Des. Discovery. 2014,
12, 138-149.
5. S. Manohar, A. Thakur, R. Bhatia, S. Walia, P. Ponnan and D. S. Rawat “Antibacterial and
Antioxidant Activity Evaluation of Novel Symmetrical and Unsymmetrical C5-Curcuminoids” Ind. J.
Chem. Sect B. 2015, 54, 1235-1246.
6. M. Tripathi, S. I. Khan, A. Thakur, P. Ponnan and D. S. Rawat “4-Aminoquinoline-pyrimidine-
aminoalkanols: Synthesis, in vitro antimalarial activity, docking studies and ADME predictions” New
J. Chem., 2015, 39, 3474-3483.
7. U. C. Rajesh, R. kholiya, A. Thakur and D. S. Rawat “[TBA][Gly] ionic liquid: Green and sustainable
approach for the synthesis of 3-substituted indoles and indolyl-4H-chromenes”Tetrahedron Lett., 2015,
56, 1790-1793.
8. A. Thakur, P. L. Reddy, M. Tripathi and D. S. Rawat “Facile construction of 3-indolochromenes and
3-indoloxanthenes via EDDF catalyzed one-pot three component reactions” New J. Chem., 2015, 39,
6253-6260.
Manuscript(s) Under Preparation
1. A. Thakur et. al. “Anticancer and antimalarial activity of 9-aminoacridine-pyrimidine conjugates
tethered through piperazine as a rigid linker”.
2. A. Thakur et. al. “In vitro anticancer activity and pre in vivo study in Xenograft models of 4-
aminoquinoline-pyrimidine hybrid”.
3. A. Thakur et. al. “Highly promising in vitro and in vivo antimalarial activity of 4-aminoquinoline-
pyrimidine hybrids”.
4. A. Thakur et. al. “Design, synthesis and evaluation of in vitro antimalarial and anticancer activity
together with in silico studies of 4-aminoquinoline-pyrimidine conjugates”.
5. Anuj Thakur et. al. “Polyvinyl alcohol-sulphonic acid (PVA-SO3H): A novel and recyclable
organocatalyst for N-formylation of amines under metal free and neat condition”
Patent
 Diwan S. Rawat, Sunny Manohar, Ummadisetty Chinna Rajesh, Deepak Kumar, Anuj Thakur, Mohit
Tripathi, Panyala Linga Reddy, Shamseer Kulangara Kandi, Satyapavan Vardhineni, Kwang-Soo, and
Chun-Hyung Kim, Amino-quinoline based hybrids and uses thereof, PCT/US2013/28329 (February
28, 2013).
Conferences/ Seminars/ Workshops attended : (in chronological order)
 Attended Workshop on “Computational Methods in Physical, Geological Modeling and Drug
Designing” National Academy of Sciences and University of Allahabad, Allahabad, India, September
29th
-1st
October, 2011.
 Attended Seminar cum Hands-on Training on “Computational Protein Structure Prediction”
Department of Chemistry, Jamia Hamdard, Hamdard Nagar, New Delhi, November 28th
-29th
, 2011.
 Presented poster “4-aminoquinoline based scaffolds as potential antimalarial agents” at 16th
ISCB-
2012 International Conference of Indian Society of Chemist and Biologist, Sholapur University,
Sholapur, Maharashtra, January 21st
-24th
, 2012.
 Presented poster “Novel 4-aminoquinoline based hybrids with improved in vitro and in vivo
antimalarial activity” at Emerging Trends in Development of Drugs and Devices (ETDDD)”
University of Delhi, Delhi, January 21st
-23rd
, 2013.
 Presented poster “Novel 4-aminoquinoline based hybrids with improved in vitro and in vivo
antimalarial activity” at 19th
ISCB-2013 International Conference of Indian society of Chemist and
Biologist, Mohanlal Sukhadia University, Udaipur, Rajasthan, India, March 2nd
-5th
, 2013
 My work “Synthesis and anticancer activity of C5-curcuminoids” was presented at 246th
ACS
National Meeting & Exposition, Indianapolis, IN, United States, September 8-12, 2013 (2013), MEDI-
105.
 Presented poster “Computational strategy to design novel C5-curcuminoids against cancer” at
Recent Advances in Computational Drug Design, Indian Institute of Science, Bangalore, September
16-17, 2013.
 Presented poster “Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogues of
curcumin: Anticancer activity evaluation and mode of action study” at ICCB-2014 International
Conference on Chemical Biology Disease Mechanism and Therapeutics, CSIR-IICT, Hyderabad,
Telangana, India, February 6-8, 2014.
 Presented poster “Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogues of
curcumin: Anticancer activity evaluation and mode of action study” at 20th
ISCB-2014
International Conference of Indian society of Chemist and Biologists, Department of Chemistry,
University of Delhi, Delhi, India, March 1- 4, 2014.
 Attended Workshop on “Information Literacy & Competency” Delhi University Library System,
University of Delhi, Delhi, India, December 4th
, 2014
Personal Details
Name : Anuj Thakur
Father’s Name : Nawal Kishore
Permanent Address : B-185 B, Lajpat Nagar,
Sahibabad, Ghaziabad,
U.P - 201005
Gender : Male
Nationality : Indian
Date of Birth : 13 May 1986
Age : 29 years
Languages Known : Hindi, English
Marital status : Single
References
Prof. Diwan S. Rawat
Department of Chemistry
University of Delhi
Delhi, 110007
Email: diwansrawat @ gmail.com
Prof. M. Nath
Department of Chemistry
University of Delhi
Delhi, 110007
Email: mnathchemistry @ gmail.com
Prof. A. K. Prasad
Department of Chemistry
University of Delhi
Delhi, 110007
Email: ashokenzyme@yahoo.com
Praveen Verma
Scientific Officer C
Department of Atomic energy
BARC, Mumbai
Email: praveen8970 @ gmail.com
Last updated: 7/12/2015 Signature
Place: Delhi

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CURRICULUM VITAE

  • 1. CURRICULUM VITAE ANUJ THAKUR (B.Sc, M. Sc, Ph.D.) Correspondence Address B-185 B, Lajpat Nagar, Sahibabad, Ghaziabad, U.P – 201005 Email: anujt13@gmail.com Mobile: +91-9911754636 Career Objective  To reach such a challenging and rewarding position as a Researcher and educator that demands me to apply my entire intellectuality and to retain my identity in the society by achieving the summit of perfection in my duties and responsibilities Current Position  Research Associate at Mankind Pharma, one of the fastest growing pharmaceutical companies of India. Job profile includes :-  Designing the synthetic route and executing the multistep organic synthesis of impurities associated with active pharmaceutical ingredient (API)  Literature search for designing synthetic route using Scifinder.  Characterization of products via their Analytical data (NMR, Mass, HPLC, IR etc.). Doctorate Details  Thesis entitled “Design, Facile Synthesis and Development of Novel Molecular Hybrids as Therapeutic Agents” has been submitted on 15/7/2015 and defended on 19/1/16. Supervisor and Affiliation Name: Diwan S. Rawat Designation: Professor (Full) Department: Department of Chemistry Institution: University of Delhi, Delhi, India Research Work  Design and synthesis of novel heterocyclic anti-cancer, anti-malarial and anti-Parkinsonian compounds based on the recently introduced concept of molecular hybridization.  Synthesized library of quinoline-pyrimidine hybrids and piperidone based C5-curcuminoids through multi-step synthesis.  Designed and synthesized novel organo-catalytic systems for catalyzing various organic transformations of synthetic importance, including MCRs.  Reactions like Claisen–Schmidt condensation, knoevenagel condensation, sonogashira coupling, various nucleophilic substitution reactions, reduction etc were performed at different stages of course.  In-silico studies of most active compounds were performed using Schrodinger Maestro software
  • 2. Awards & Fellowship  At present availing Senior Research Fellowship from Council of Scientific and Educational Research, India since January 2013.  Received Junior Research Fellowship from Council of Scientific and Educational Research, India from January 2011 to December 2012.  Qualified JOINT CSIR-UGC TEST FOR JUNIOR RESEARCH FELLOWSHIP (JRF) ANDNATIONAL ELIGIBILITY FOR LECTURESHIP (NET) in Chemical Sciences, June 2010 Academic Qualifications Degree/Examination University/Board Period % Marks Ph.D. (Chemistry) Dept. of Chemistry, University of Delhi Jan-2011 to Jan-2016 - M.Sc. (Organic Chemistry) Dept. of Chemistry, University of Delhi 2008-2010 62.81 B.Sc.Gen (Group A) Zakir Hussain College, University Of Delhi 2004-2007 66.14 10+2 CBSE 2004 72.8 10th ICSE 2002 72.5 Professional Skills  Good knowledge of synthetic organic chemistry, excellent laboratory skills and synthetic route designing skills with a strong capacity to conduct independent research.  Proficient in handling reactions from mg to gram scale and in purifying the crude product through column chromatography  Instrument handling like IR, UV, Microwave  Proficient in characterizing compounds through spectroscopic techniques  Skilled in scientific content writing  Working knowledge of Microsoft Word, Excel, Power-Point  Proficient in software packages like ChemDraw, Delta, Origin.  Basic knowledge of Schrodinger Maestro (QSAR and docking) Research Publications 1. A. Thakur, M. Tripathi, U. Chinna. Rajesh and D. S. Rawat “Ethylenediammonium-diformate (EDDF) in PEG600: An efficient ambiphilic novel catalytic system for the one-pot synthesis of 4H- pyrans via Knoevenagel condensation” RSC Adv., 2013, 3, 18142- 18148. 2. A. Thakur, S. I. Khan and D. S. Rawat “Synthesis of piperazine tethered 4-aminoquinoline-pyrimidine hybrids as potent antimalarial agents” RSC Adv., 2014, 4, 20729-20736. 3. A. Thakur, S. Manohar, C. E. V. Gerena, B. Zayas, V. Kumar, S. V. Malhotra and D. S. Rawat “Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study” Med. Chem. Commun., 2014, 5, 576-586. 4. S. Manohar, A.Thakur, S. I. Khan, G. Sun, N. Ni, B. Wang and D. S. Rawat “Synthesis of Unsymmetrical C5-Curcuminoids as Potential Anticancer Agents” Lett. Drug Des. Discovery. 2014, 12, 138-149. 5. S. Manohar, A. Thakur, R. Bhatia, S. Walia, P. Ponnan and D. S. Rawat “Antibacterial and Antioxidant Activity Evaluation of Novel Symmetrical and Unsymmetrical C5-Curcuminoids” Ind. J. Chem. Sect B. 2015, 54, 1235-1246.
  • 3. 6. M. Tripathi, S. I. Khan, A. Thakur, P. Ponnan and D. S. Rawat “4-Aminoquinoline-pyrimidine- aminoalkanols: Synthesis, in vitro antimalarial activity, docking studies and ADME predictions” New J. Chem., 2015, 39, 3474-3483. 7. U. C. Rajesh, R. kholiya, A. Thakur and D. S. Rawat “[TBA][Gly] ionic liquid: Green and sustainable approach for the synthesis of 3-substituted indoles and indolyl-4H-chromenes”Tetrahedron Lett., 2015, 56, 1790-1793. 8. A. Thakur, P. L. Reddy, M. Tripathi and D. S. Rawat “Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions” New J. Chem., 2015, 39, 6253-6260. Manuscript(s) Under Preparation 1. A. Thakur et. al. “Anticancer and antimalarial activity of 9-aminoacridine-pyrimidine conjugates tethered through piperazine as a rigid linker”. 2. A. Thakur et. al. “In vitro anticancer activity and pre in vivo study in Xenograft models of 4- aminoquinoline-pyrimidine hybrid”. 3. A. Thakur et. al. “Highly promising in vitro and in vivo antimalarial activity of 4-aminoquinoline- pyrimidine hybrids”. 4. A. Thakur et. al. “Design, synthesis and evaluation of in vitro antimalarial and anticancer activity together with in silico studies of 4-aminoquinoline-pyrimidine conjugates”. 5. Anuj Thakur et. al. “Polyvinyl alcohol-sulphonic acid (PVA-SO3H): A novel and recyclable organocatalyst for N-formylation of amines under metal free and neat condition” Patent  Diwan S. Rawat, Sunny Manohar, Ummadisetty Chinna Rajesh, Deepak Kumar, Anuj Thakur, Mohit Tripathi, Panyala Linga Reddy, Shamseer Kulangara Kandi, Satyapavan Vardhineni, Kwang-Soo, and Chun-Hyung Kim, Amino-quinoline based hybrids and uses thereof, PCT/US2013/28329 (February 28, 2013). Conferences/ Seminars/ Workshops attended : (in chronological order)  Attended Workshop on “Computational Methods in Physical, Geological Modeling and Drug Designing” National Academy of Sciences and University of Allahabad, Allahabad, India, September 29th -1st October, 2011.  Attended Seminar cum Hands-on Training on “Computational Protein Structure Prediction” Department of Chemistry, Jamia Hamdard, Hamdard Nagar, New Delhi, November 28th -29th , 2011.  Presented poster “4-aminoquinoline based scaffolds as potential antimalarial agents” at 16th ISCB- 2012 International Conference of Indian Society of Chemist and Biologist, Sholapur University, Sholapur, Maharashtra, January 21st -24th , 2012.  Presented poster “Novel 4-aminoquinoline based hybrids with improved in vitro and in vivo antimalarial activity” at Emerging Trends in Development of Drugs and Devices (ETDDD)” University of Delhi, Delhi, January 21st -23rd , 2013.  Presented poster “Novel 4-aminoquinoline based hybrids with improved in vitro and in vivo antimalarial activity” at 19th ISCB-2013 International Conference of Indian society of Chemist and Biologist, Mohanlal Sukhadia University, Udaipur, Rajasthan, India, March 2nd -5th , 2013  My work “Synthesis and anticancer activity of C5-curcuminoids” was presented at 246th ACS National Meeting & Exposition, Indianapolis, IN, United States, September 8-12, 2013 (2013), MEDI- 105.
  • 4.  Presented poster “Computational strategy to design novel C5-curcuminoids against cancer” at Recent Advances in Computational Drug Design, Indian Institute of Science, Bangalore, September 16-17, 2013.  Presented poster “Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogues of curcumin: Anticancer activity evaluation and mode of action study” at ICCB-2014 International Conference on Chemical Biology Disease Mechanism and Therapeutics, CSIR-IICT, Hyderabad, Telangana, India, February 6-8, 2014.  Presented poster “Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogues of curcumin: Anticancer activity evaluation and mode of action study” at 20th ISCB-2014 International Conference of Indian society of Chemist and Biologists, Department of Chemistry, University of Delhi, Delhi, India, March 1- 4, 2014.  Attended Workshop on “Information Literacy & Competency” Delhi University Library System, University of Delhi, Delhi, India, December 4th , 2014 Personal Details Name : Anuj Thakur Father’s Name : Nawal Kishore Permanent Address : B-185 B, Lajpat Nagar, Sahibabad, Ghaziabad, U.P - 201005 Gender : Male Nationality : Indian Date of Birth : 13 May 1986 Age : 29 years Languages Known : Hindi, English Marital status : Single References Prof. Diwan S. Rawat Department of Chemistry University of Delhi Delhi, 110007 Email: diwansrawat @ gmail.com Prof. M. Nath Department of Chemistry University of Delhi Delhi, 110007 Email: mnathchemistry @ gmail.com Prof. A. K. Prasad Department of Chemistry University of Delhi Delhi, 110007 Email: ashokenzyme@yahoo.com Praveen Verma Scientific Officer C Department of Atomic energy BARC, Mumbai Email: praveen8970 @ gmail.com Last updated: 7/12/2015 Signature Place: Delhi