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   The goal of science is to investigate and
    understand nature, to explain events in nature,
    and to use those explanations to make useful
    predictions.

   Science – an organized way of using evidence
    to learn about the natural world
   Observation – involves using one or more of the
    senses – Which are?


       sight
       hearing
       touch
       smell
       taste
   Data – information gathered from
    observation.

    Two types of observation –
    Quantitative – involves numbers. Examples?

    Qualitative – involves characteristics that
    cannot be easily measured or counted.
    Examples?
   Inference – a logical interpretation based on
    prior knowledge and experience.

   Hypothesis – a possible explanation for a set of
    observations or an answer to scientific
    questions.

    *It can be useful ONLY if it can be tested.
   5 Steps
   1) Stating the Problem– Identify a problem to
    solve.

   2) Forming a Hypothesis- Example – Life can arise
    from not living matter or spontaneous generation.
    (Maggots appear on meat)

   Hypothesis formulated by Francesco Redi in
    1600s – Flies produce maggots.
   3) Setting Up a Controlled Experiment- Factors that
    can be changed in an experiment are called
    variables. Examples:

    temperature, light, time

    *A hypothesis should be tested by an experiment
    in which only one variable is changed at a time. All
    other variables should be kept unchanged, or
    controlled.

    Why?    If multiple variables are changed, one would
            not be able to tell which variable is
            responsible for the observed results
   Manipulated variable – the variable that is
    purposely changed. (independent v.)

   Responding variable – the variable that changes
    as a result of the manipulated variable.
    (dependent v.)
   4) Recording and Analyzing Results

   5) Drawing a Conclusion
      Hypothesis accepted or rejected?

      If accepted, the test can repeated again for validity.
      If rejected, the experiment can be altered.

     To make results more valid:
     (1) – Repeat the experiment
     (2) - Increase sample size
   Experiments can be retested (like Redi’s)
    and/or improved with further investigation.

   Examples – Needham, Spallazani, and Pasteur

   In 1700s, microorganisms were discovered by
    Anton van Leeuwenhoek.
Needham and Spallazani’s Work




                          Both scientists proved existing
Filled with
microorganisms            organisms are produced only by
                          existing organisms.
   Pasteur proved that spontaneous generation
    was incorrect; he said that all living things
    come from other living things.

   His work was different than Needham and
    Spallazani’s because he involved air.
Tube uncut –
microorganisms not
present.                                 Tube cut –
                                         microorganisms present




                     An experiment was finally revised over
                     a 200 year period.
   Theory – applies to well-tested explanation
    that unifies a broad range of observation.

- starts off initially as hypothesis but then
  becomes so well supported.
   Characteristics of Living things
    1) Living things are made up of units called
    cells.

    Cell – collection of living matter enclosed by a
    barrier that separates the cell from its
    surroundings.

    Two types of organisms – multicellular and
    unicellular
   2) Living things reproduce.

    Two types of reproduction:

    sexual reproduction – involves two different parents
    (multicellular organisms)




    asexual reproduction – involves only one
    parent
    (unicellular organisms)
   3) Living things are based on a universal
    genetic code.


    DNA - the genetic code that determines the
    inherited traits of every organism on Earth




    4) Living things grow and develop.
   5) Living things obtain and use materials and
    energy.

 Metabolism – combination of chemical
  reactions in which an organism builds up or
  breaks down materials as it carries out its life
  processes
- Energy needed to live
   6) Living things respond to their environment.

    Organisms live in constantly changing
    environments.

7) Living things maintain a stable internal
environment.

Homeostasis – process by which organisms keep
their internal conditions relatively stable (breathing)
- if disrupted in major way, organisms will not
survive
   8) Living things evolve, or change over time.




Branches of Biology
The many levels at which life can be studied include
molecules, cells, organisms, populations of a single
organism, communities of populations living in the
same area, and the biosphere.
   Most scientists use the metric system when
    collecting data and performing experiments.

   Metric system – decimal system of
    measurement whose units are based on
    certain physical standards
   scaled on multiples of 10.
   Microscopes –devices that produce magnified
       images of structures that are too small to see
       with the unaided eye.


Light microscopes produce
magnified images by focusing
visible light rays. Electron
microscopes produce magnified
images by focusing beams of
electrons.
   Cell Culture – group of cells that develop from a
    single original cell.

    Purpose – To test cell responses under controlled
    conditions and to study interactions between cells.
Cell fractionation – a
technique in which cell parts
(organelles) can be
separated.

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Unit 1 chapter 1 (revised)

  • 1.
  • 2. The goal of science is to investigate and understand nature, to explain events in nature, and to use those explanations to make useful predictions.  Science – an organized way of using evidence to learn about the natural world
  • 3. Observation – involves using one or more of the senses – Which are? sight hearing touch smell taste
  • 4. Data – information gathered from observation. Two types of observation – Quantitative – involves numbers. Examples? Qualitative – involves characteristics that cannot be easily measured or counted. Examples?
  • 5. Inference – a logical interpretation based on prior knowledge and experience.  Hypothesis – a possible explanation for a set of observations or an answer to scientific questions. *It can be useful ONLY if it can be tested.
  • 6. 5 Steps  1) Stating the Problem– Identify a problem to solve.  2) Forming a Hypothesis- Example – Life can arise from not living matter or spontaneous generation. (Maggots appear on meat)  Hypothesis formulated by Francesco Redi in 1600s – Flies produce maggots.
  • 7. 3) Setting Up a Controlled Experiment- Factors that can be changed in an experiment are called variables. Examples: temperature, light, time *A hypothesis should be tested by an experiment in which only one variable is changed at a time. All other variables should be kept unchanged, or controlled. Why? If multiple variables are changed, one would not be able to tell which variable is responsible for the observed results
  • 8. Manipulated variable – the variable that is purposely changed. (independent v.)  Responding variable – the variable that changes as a result of the manipulated variable. (dependent v.)
  • 9.
  • 10.
  • 11. 4) Recording and Analyzing Results  5) Drawing a Conclusion Hypothesis accepted or rejected? If accepted, the test can repeated again for validity. If rejected, the experiment can be altered. To make results more valid: (1) – Repeat the experiment (2) - Increase sample size
  • 12. Experiments can be retested (like Redi’s) and/or improved with further investigation.  Examples – Needham, Spallazani, and Pasteur  In 1700s, microorganisms were discovered by Anton van Leeuwenhoek.
  • 13. Needham and Spallazani’s Work Both scientists proved existing Filled with microorganisms organisms are produced only by existing organisms.
  • 14. Pasteur proved that spontaneous generation was incorrect; he said that all living things come from other living things.  His work was different than Needham and Spallazani’s because he involved air.
  • 15. Tube uncut – microorganisms not present. Tube cut – microorganisms present An experiment was finally revised over a 200 year period.
  • 16. Theory – applies to well-tested explanation that unifies a broad range of observation. - starts off initially as hypothesis but then becomes so well supported.
  • 17. Characteristics of Living things 1) Living things are made up of units called cells. Cell – collection of living matter enclosed by a barrier that separates the cell from its surroundings. Two types of organisms – multicellular and unicellular
  • 18. 2) Living things reproduce. Two types of reproduction: sexual reproduction – involves two different parents (multicellular organisms) asexual reproduction – involves only one parent (unicellular organisms)
  • 19. 3) Living things are based on a universal genetic code. DNA - the genetic code that determines the inherited traits of every organism on Earth 4) Living things grow and develop.
  • 20. 5) Living things obtain and use materials and energy.  Metabolism – combination of chemical reactions in which an organism builds up or breaks down materials as it carries out its life processes - Energy needed to live
  • 21. 6) Living things respond to their environment. Organisms live in constantly changing environments. 7) Living things maintain a stable internal environment. Homeostasis – process by which organisms keep their internal conditions relatively stable (breathing) - if disrupted in major way, organisms will not survive
  • 22. 8) Living things evolve, or change over time. Branches of Biology The many levels at which life can be studied include molecules, cells, organisms, populations of a single organism, communities of populations living in the same area, and the biosphere.
  • 23. Most scientists use the metric system when collecting data and performing experiments.  Metric system – decimal system of measurement whose units are based on certain physical standards  scaled on multiples of 10.
  • 24.
  • 25. Microscopes –devices that produce magnified images of structures that are too small to see with the unaided eye. Light microscopes produce magnified images by focusing visible light rays. Electron microscopes produce magnified images by focusing beams of electrons.
  • 26. Cell Culture – group of cells that develop from a single original cell. Purpose – To test cell responses under controlled conditions and to study interactions between cells.
  • 27. Cell fractionation – a technique in which cell parts (organelles) can be separated.