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Optomechanical measurement and FE modeling
of tympanic membrane mechanics
Jef Aernouts
Laboratory of Biomedical Physics (BIMEF)
University of Antwerp

Presentation at Philips Group Innovation
October 5, 2012
Optomechanical measurement and FE modeling
of tympanic membrane mechanics




                                             1
The human ear




       tympanic
       membrane



                  2
Function of the ear

Convert sound (20-20000 Hz) > nerve activity in our brain




             What is role middle ear?
                                                            3
Why study TM mechanics?

• Middle ear finite element modeling

                                                   tympanic membrane!




          normal
(Aerts J, Aernouts J. 2012)                            reconstructed
                                diseased               (Kelly et al., 2003)
                              (Gan et al., 2009)
                                                                              4
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  5
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  6
Human tympanic membrane

- Base diameter: 9 mm
- Apex height: 1.7 mm




                            7
Needle indentation

• Approach
  - Apply indentations
  - Measure forces




                         (1) TM, (2): force transducer,
                         (3): piston, (4): LVDT , (5): signal
                         generator, (6): feedback control unit


                                                                 8
Needle indentation

• Approach
  - Apply indentations
  - Measure forces


• Sample preparation




                                  9
Needle indentation

• Approach
  - Apply indentations
  - Measure forces


• Sample preparation

• Shape measurement




                                  10
Needle indentation
                             In rest
• Approach
  - Apply indentations
  - Measure forces


• Sample preparation

                             Indented
• Shape measurement

• Finite element model



                                        11
Needle indentation

• Approach
  - Apply indentations
  - Measure forces


• Sample preparation

• Shape measurement

• Finite element model
  - Fit experiments



                                  12
13
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  14
TM vibrations

• Sample




                           15
TM vibrations

• Sample

• Stroboscopic holography
  - Sounds: 0.5 kHz –
    19 kHz, 80-120 dB
  - Full-field displacement




                                 16
Holography

• Principle




                           CCD




                             17
Holography

• Principle

• Stroboscopic holography




                             18
probe microphone



                  speaker

                                     holography setup




sample




         camera
FE model

• Geometry (from micro-CT)
• Boundary conditions & Loadings




                     sound wave
                                   20
TM full-field displacement


- Measured with stroboscopic holography:




                                           21
TM full-field displacement


- Measured with stroboscopic holography:
- Finite element outcome




                                           22
Outline

1. Tympanic membrane elasticity

2. Tympanic membrane vibrations

3. Middle ear modeling




                                  23
Middle ear FE model results




1000 Hz     7000 Hz      16000 Hz
 (x8e3)      (x3e4)       (x2e5)



                                    24
Thanks for your attention!

• Questions? I’m all ears…




                                   25
TM curvature

• Cochlear load at umbo (tip malleus)
• Natural curved versus artificially flat




                                            26
TM curvature
                           800 Hz – 4 kHz:
• Umbo velocity response   17.5 dB difference




                                                27

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Optomechanical measurement and FE modeling of tympanic membrane mechanics