urea cycle.pptx

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urea cycle

Unit III
Urea Cycle
Isha Rani
(Assistant Professor)
MMCP, MMU-Mullana

Urea Cycle and Its Disorder
• Urea is the end product of protein metabolism.
• Urea synthesized in liver and transported to kidney for excretion in
urine.
• It is also known as Krebs-Henseleit Cycle.
• Urea has two amino groups, one drived from NH3 and other from
aspartate.
• Urea synthesis is a five step cyclic process.
• First two enzymes present in mitochondria.
• Rest of enzymes present in cytosol.

Urea cycle

Energetics
• Urea cycle consumes 4 ATP.

Thank You

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urea cycle.pptx

1. Unit III Urea Cycle Isha Rani (Assistant Professor) MMCP, MMU-Mullana

2. Urea Cycle and Its Disorder • Urea is the end product of protein metabolism. • Urea synthesized in liver and transported to kidney for excretion in urine. • It is also known as Krebs-Henseleit Cycle. • Urea has two amino groups, one drived from NH3 and other from aspartate. • Urea synthesis is a five step cyclic process. • First two enzymes present in mitochondria. • Rest of enzymes present in cytosol.

4.

5. Energetics • Urea cycle consumes 4 ATP.