Survivin Monomer Plays an Essential Role in Apoptosis Regulation Mar.pdf

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Survivin Monomer Plays an Essential Role in Apoptosis Regulation Marat S. Pavlyukov, Nadezhda V. Antipova, Maria V. Balashova, Tatjana V. Vinogradova, Evgenij P. Kopantzev, and Mihail I. Shakhparonov1 What hypothesis is proposed by the authors in the above study? Solution Survivin monomer was unable to dimerize and can interact with smac/ DIABLO both in vivo and in vitro.Our hypothesis further suggested that survivin can bind to XIAP and protect cells from death..

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1) Name the seven layers of the OSI network model, and 2) enumerate security issues at each level. I have done the first one for you as an example: Layer 1 - Physical: theft, bit errors, denial of service, noise, signal errors, RF interference, removable media, open wall ports, flooding, natural disasters, EMP bomb. Solution The seven layers of the OSI model are as follows: Layer 1-Physical layer: The security issues at this layer are theft, bit errors, denial of service, noise, signal errors, RF interference, removable media, open wall ports, flooding, natural disasters, EMP bomb. Layer 2-Data link layer: The security issues that can occur at this layer are MAC flooding, disruption in the flow of the data. Layer 3-Network layer: The security issues are: ICMP Flooding, load on firewall, loss of confidentiality. Layer 4-Transport Layer: SYN flood, Smurf Attack, Layer 5-Session layer: The security issues that can occur at this layer can occur during the inter- machine communication. Layer 6-Presentation Layer: The poor handling of input (malicious) can lead to crashes. Layer 7-Application Layer: This layer is most prevalent to attack by hackers. At this layer, the entire application can be manipulated, user data can be stolen. It can lead to destruction of the entire network. This is also known as Denial of Service attack..

1) Name the seven layers of the OSI network model, and 2) enumerate .pdf

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8. Eenee, Meanie, and Miney each have a capital balance of $84,000 in their three-person partnership and vote to allow Martin Moe to contribute $96,000 in cash to the partnership for a one-fourth interest. Which of the following is an effect of this transaction? A. A gain of $12,000. B. A loss of $12,000. C. Miney’s capital balance increases by $4,000. D. Miney’s capital balance increases by $3,000. Solution Since Martin Moe joined partnership with 1/4th interest, hence the interest of old partners in the business remains unaffected. But since martin brought $12,000 more funds which will be treated as Goodwill to the firm and will get distributed in partners\' capital in their profit-sharing ratio. Therefore Miney\'s capital balance increases by $3000..

8. Eenee, Meanie, and Miney each have a capital balance of $84,000 i.pdf

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Your boss has instructed you to make up a medium for growing Gram-negative prokaryotes. She wants you to be able to grow 100 mg/l of volatile suspended solids. You looked up some papers on the microorganisms and found that the empirical chemical formula for them is C_5H_7O_2NP_0.1. What are the minimum concentrations of NH^+_4 -N and PO_4-P that you must add to your medium? Solution Phosphorus and Nitrate were found at a ratio of 1:10 in microbes as studied in the example. So 10+1=11 parts weighs 100 mg, i.e. 100/11=9.090 mg PO4-P and rest 90.909 mg NH4+-N in 1 litre is suggested for your medium..

[Python] [Singly-linked list] [Element insertion] Consider the follo.pdf

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why Cu, Pb, and Sn were metals used in early civilizations ? Solution Copper(Cu), Lead(Pb) and Sn(Tin) are among the metals which were used by the pre-historic men. Copper in its native pure form could be hammered to different shapes. Archaeological evidence suggests that copper was first used between 8,000 and 5,000 B.C., most likely in the regions known now as Turkey, Iran, Iraq and the Indian subcontinent. It is most likely that before the invention of the metallurgical methods, the native copper in pure form was used. They could use simple hammering and forging to harden the copper. Also these metals were malleable so they could be molded into different shapes. Then annealing became the first step towards metallurgy when they discovered that heating the copper makes it easy to work with. Other superior alloys such as Bronze were only possible after further enhancements in metallurgy, such as smelting process. So this is the reason that only these metals were used in early times..

why Cu, Pb, and Sn were metals used in early civilizations Solu.pdf

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Which scenario is the least likely to be supported by the theory of evolution?a. All species that have ever lived are genetically related.b. Pigs, dolphins, bats, and humans share a common ancestor.c. Humans evolved from chimpanzees.d. Dogs were domesticated from their gray wolf ancestor.e. Repeated exposure to DDT can lead to pesticide resistance in mosquitos. Solution c. Humans evolved from chimpanzees . This is because genetic evidence suggests that though humans and chimps are closely related, chimps do not represent our ancestors and both the groups have diverged about 4.4 m.y ago but have a common ancestor. Recent evidence suggests that the fossil Ardipithecus ramidus (4.4 m Y)may have been our common ancestor but walked neither like chimps nor like humans and had intermediate form of walking..

Which scenario is the least likely to be supported by the theory of .pdf

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What is the difference between neurotransmitters and neuropeptides? Neurotransmitters are small protein molecules and neuropeptides are large ones. Neurotransmitters are small hydrophilic molecules and neuropeptides are small proteins. Some neuropeptides can act on cells, whereas neurotransmitters cannot. Neuropeptides are generated by neuronal cells but do not transmit signals. Solution Answer: Correct answer is C) Some neuropeptides can act on distant cells, whereas Neurotransmitters cannot. Explanation: Neurotransmitters are small hydrophilic molecules due to which they are unable to cross the plasma membrane. Nervous system cells rapidly communicate with distant cells, this is achieved as the nerve cells releases the neurotransmitters (from the nerve terminal) in close proximity to the target cells (via a mechanism called as synpatic signaling). Thus neurotransmitter do not travel to the distant cells. Neuropeptides on the other hand can be released in the blood with peripheral effects..

What is the difference between neurotransmitters and neuropeptides .pdf

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5) The US government is spying on Switzerland. They believe Switzerland is developing a computervirus which will melt all the computers in the US. They are sending in agent 00111 to investigate. Hewill gather evidence, and if it is strong enough the president will have no choice but to declare war. a) What is the definition of power in this scenario? b) What alpha would you suggest and why (explain which consequence you are avoiding) Solution.

5) The US government is spying on Switzerland. They believe Switzerl.pdf

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To qualify for the partial exclusion of gain on the sale or exchange of Qualified Small Business Stock the taxpayer must have held the stock for more than_years before the sale or exchange A) two B) three C) four D) five Solution As per the section 1202, to qualify for the partial exclusion of gain on the sale or exchange of Qualified Small Business Stock the taxpayer must have held the stock for more than FIVE years..

To qualify for the partial exclusion of gain on the sale or exchange.pdf

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These questions are for Java. 1. name of Java class with methods and constants for manipulating the style and size of characters? 2. name of method to be called when GUI components need to be refreshed? 3. code that performs a task in response to an event? 4. link a GUI component to an event handler (one word answer) Solution 1)we hava class called Font in java.awt package in that these are the constants which will change the size and style of th text i)BOLD ii)ITALIC iii)PLAIN and there is constructor called i)Font(String name,int style,int size) which is change your text size and method ii)public Font deriveFont(int style, AffineTransform trans) 2)repaint() which calls the paint method affter changes have done.

These questions are for Java.1. name of Java class with methods an.pdf

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The United States Central Intelligence Agency, FBI, and National Security Agency all employee professional hackers to monitor (or potentially attack) domestic and international targets. Research this topic and describe your thoughts on the ethical aspect of this activity. Do you think that such state-sponsored hacking is justifiable? ( be elaborate with examples) Solution There are two views in this scenario. 1. State Security Now a days terrorism is increasing in a higher pace. In order to control terrorist attacks, it becomes necessary to monitor the domestic and international targets so that we can safeguard our nation. Without monitoring we may be fragile to even a small planned attack. 2. Privacy Interruption Monitoring other persons activities is necessarily a privacy issue. It would be unpleasing to other countries or its own citizens when they know that government is monitoring their activities. Even now a days, There are many people who are unpleased of customized advertisements popping up in the webpages. From national safety perspective, It\'s justifiable to monitor domestic and international targets provided they don\'t use it to exploit others..

The United States Central Intelligence Agency, FBI, and National Sec.pdf

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The study of consumer choose one brand over another and how they make.pdf

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statistics Which is not true of p-values? Select one: When they are small, we want to reject Ho They measure the probability of an incorrect decision They show the chance of Type I error if we reject Ho They do not require a to be specified a priori Solution It is OPTION C: They show the chance of a type I error if we reject Ho. ******************** It is actually the level of significance, alpha, which does this, not the P value..

statistics Which is not true of p-values Select one When they are.pdf

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Summarize the article \"Towards an Aesthetic of popular music\" by Simon Frith in 500 words by following these steps: - the central idea of the passage - what, who, why, where, when and how - the author\'s conclusion - the subject of the description and it\'s key feature(s) Solution Review of the Article The article Towards an Aesthetic of popular music is written by Simon Frith. The article studies the question of value judgement of pop music And also the judgement the shaping of listening popular music. Here the Frith rejects serious music matters also the poupular music is aesthetically wothless. He believes that it is sociological constructive approach. He link between certian social groups and the popular music. He examined that popular music is the product of social taste. The music provides the ethical value of the people. He claims that the pop music is a kind of Althussarian ideological apparutus it explained the people what they have. He believes that the popular music is not taste but create taste of the people. The pop chart creates the taste of the communities. He belives that the Pop music is created the personnal appropriation rather other forms of the culture. On the formation of this, it creates a personal identity..

Summarize the article Towards an Aesthetic of popular music by S.pdf

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public void turnRight(double degrees) { rotationInDegrees + - = degrees; } public void turnLeft(double degrees) { rotationInDegrees - = degrees; } Actor public class Actor { private EZImage pikachu; // Member variable to store bug picture private int x, y, startx, starty; // Member variables to store x, y, startx, starty private int destx, desty; // Member variables to store destination values private long starttime; // Member variable to store the start time private long duration; // Member variable to store the duration private boolean interpolation; // Member variable that is set to true if it is in the interpolation state // ********* SCALE private float currentScale = 1; private float destScale = 1; private float startScale = 1; private boolean interpolationScale; // Constructor for RCBug takes 3 parameters public Actor(String filename,int posx, int posy){ // Set the current position of the bug x=posx;y=posy; // Create the image of the bug pikachu = EZ.addImage(filename, posx, posy); // Move it to the starting position. This is actually redundant. pikachu.translateTo(x,y);; // Set interpolation mode to false initially interpolation = false; interpolationScale = false; } // Set the destination by giving it 3 variables // Dur means duration and is measured in seconds //public void setDestination(int posx, int posy, long dur){ public void moveto(int posx, int posy, long dur){ // Set destination position and duration // Convert seconds to miliseconds destx = posx; desty = posy; duration = dur*1000; // Get the startting time (i.e. time according to your computer) starttime = System.currentTimeMillis(); // Set the starting position of your bug startx=x; starty=y; // Set interolation mode to true interpolation = true; interpolationScale = false; } // ********* SCALE public void setScale(float s, float dur){ destScale = s; starttime = System.currentTimeMillis(); startScale = currentScale; interpolationScale = true; } // If you?re in interpolation state then return true, else false. public boolean moving() { return interpolation; } // ********* SCALE public boolean scaling() { return interpolationScale; } // This moves the bug based on the current time and elapsed time according to the interpolation equation public void go(){ // If interpolation mode is true then do interpolation if (interpolation == true) { //linear interpolation // Normalize the time (i.e. make it a number from 0 to 1) float normTime = (float) (System.currentTimeMillis() - starttime)/ (float) duration; // Calculate the interpolated position of the bug x = (int) (startx + ((float) (destx - startx) * normTime)); y = (int) (starty + ((float) (desty - starty) * normTime)); // If the difference between current time and start time has exceeded the duration // then the animation/interpolation is over. if ((System.currentTimeMillis() - starttime) >= duration) { // Set interpolation to false interpolation = false; // Move the bug all the way to the destination x = destx; y = desty; } //.

public void turnRight(double degrees) {rotationInDegrees + - = deg.pdf

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Put the following alphabetically listed structures in order for the pathway undertaken by a RBC that is starting in the pulmonary trunk and ends up in the liver aorta, atria, lung, pulmonary artery, pulmonary vein, ventricle Solution pulmonary artery,lung,pulmonary vein,atria,ventricle,aorta. This is the way the blood flows in both pulmonary and systemic circuit.From the aorta the blood(oxygenated) is pumped all over the body.

Put the following alphabetically listed structures in order for the p.pdf

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1-Which law of Mendel\'s does the monohybrid cross demonstrate, and which law does the dihybrid cross demonstrate? 2-What happens to the alleles during gamete formation for each cross Solution 1-Which law of Mendel\'s does the monohybrid cross demonstrate, and which law does the dihybrid cross demonstrate? Answer 1: The Mendel\'s law of segregation demonstrates the monohybrid cross and Mendel\'s law of independent assortment demonstrates the dihybrid cross. 2-What happens to the alleles during gamete formation for each cross. Answer 2: During gamete formation, each allele segregates. In a monohybrid cross, each parent has 2 alleles for a gene, which controls the same trait and contribute to different characteristics of that trait. For example, for flower color trait, the purple colored flowers will have 2 dominant alleles (PP) and white colored flowers will have 2 recessive alleles (pp) for the gene. All the gametes produced by one parent will have the same allele. Parent generation: PP (purple flowers) x pp (while flowers) Gametes formed: P p F1 generation: Pp (Purple flowers) In a dihybrid cross, each parent will have 4 alleles for 2 genes (2 for each gene), which controls 2 different traits and contribute to different characteristics of that trait. Parent generation: YYRR (yellow and round seeds) x yyrr (green and wrinkled seeds) Gametes formed: YR yr F1 generation: YyRr (yellow and round seeds).

1-Which law of Mendels does the monohybrid cross demonstrate, and .pdf

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PLEASE ANSWER THE QUESTIONS IN BOLD: In a certain Midwest city, a series of studies were conducted to measure both the supply and demand for physician services at various price points. The table below represents the findings across ten different employers who offer self- insured health benefits to their employees. Observations were made across time at various price points and the data below was gathered. So, for instance, at a price of $50 for an office visit, the employees of Employer 1 consumed 150 visits per week; and at a price of $60, they only consumed 140 visits, etc. At the same time and in the same city, ten different primary care practices were observed and the data table below was generated. In this case, at a price point of $50 per visit, PCP1 was willing to supply 70 visits per week, but at $60, he would supply 80 visits, etc. Question #2 – assuming that, in the short-run, the supply of physician services will remain as expressed in Table 2 above, what will happen to the market clearing price and visit quantity? Show graphically what just happened. Again, in plain English, what is happening here? After another year, new measurements are taken, and we see that the demand for services has indeed settled into that predicted in Table 3 above. We also note that physicians’ willingness to supply services at various price points has shifted. The table below shows how: Table 2 Number of visits/ year Price/visit PCP 1 PCP 2 PCP 3 PCP 4 PCP 5 PCP 6 PCP 7 PCP 8 PCP 9 PCP 10 $ 50 70 40 57 45 50 47 91 110 40 50 $ 60 80 50 67 55 60 57 101 120 50 60 $ 70 90 60 77 65 70 67 111 130 60 70 $ 80 100 70 87 75 80 77 121 140 70 80 $ 90 110 80 97 85 90 87 131 150 80 90 $ 100 120 90 107 95 100 97 141 160 90 100 $ 110 130 100 117 105 110 107 151 170 100 110 $ 120 140 110 127 115 120 117 161 180 110 120 $ 130 150 120 137 125 130 127 171 190 120 130 $ 140 160 130 147 135 140 137 181 200 130 140 Number of visits/ year Price/visit Empl 1 Empl 2 Empl 3 Empl 4 Empl 5 Empl 6 Empl 7 Empl 8 Empl 9 Empl 10 $ 50 170 220 150 140 180 200 155 162 173 150 $ 60 160 210 140 130 170 190 145 152 163 140 $ 70 150 200 130 120 160 180 135 142 153 130 $ 80 140 190 120 110 150 170 125 132 143 120 $ 90 130 180 110 100 140 160 115 122 133 110 $ 100 120 170 100 90 130 150 105 112 123 100 $ 110 110 160 90 80 120 140 95 102 113 90 $ 120 100 150 80 70 110 130 85 92 103 80 $ 130 90 140 70 60 100 120 75 82 93 70 $ 140 80 130 60 50 90 110 65 72 83 60 Table 2 Number of visits/ year Price/visit PCP 1 PCP 2 PCP 3 PCP 4 PCP 5 PCP 6 PCP 7 PCP 8 PCP 9 PCP 10 $ 50 70 40 57 45 50 47 91 110 40 50 $ 60 80 50 67 55 60 57 101 120 50 60 $ 70 90 60 77 65 70 67 111 130 60 70 $ 80 100 70 87 75 80 77 121 140 70 80 $ 90 110 80 97 85 90 87 131 150 80 90 $ 100 120 90 107 95 100 97 141 160 90 100 $ 110 130 100 117 105 110 107 151 170 100 110 $ 120 140 110 127 115 120 117 161 180 110 120 $ 130 150 120 137 125 130 127 171 190 120 130 $ 140 160 130 147 135 140 137 181 200 130 140 Solution Price/visit PCP 1 Firs.

PLEASE ANSWER THE QUESTIONS IN BOLD In a certain Midwest city, a se.pdf

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Menders experiments were conducted using garden peas. Why would humans be an awful choice for an experimental organism (give at least 3 reasons)? Give an example of an animal that would be better sorted for genetics experiments. In Mendel\'s experiments, a plant with purple flowers was crossed with a plant having white flowers. Explain why white flowers disappeared in the F_1 generation and reappeared in the F_2. Your pet rabbit has curly fur. After seeking advice from a rabbit breeder, you learn that curly fur is a dominant trait, but you want to know the precise genotype of your pet. Describe how you could find out. Describe the inheritance of ABO blood types in humans and explain why individuals with type O are universal donors while individuals with type AB are universal acceptors. Describe the nature vs. nurture debate. In your explanation, give an example of a trait that is controlled entirely by nature and one that is heavily influenced by both nature and nurture. Solution Answer: 1. Studying human genetics is unlike studying the genetics of any other organism. In many ways, humans are very poor model organisms for genetics. Long generation times make for slow progress when doing genetic crosses, which brings us to another problem with human genetics: The inability to make controlled crosses. So, any human geneticist that tried to make controlled human crosses would most likely be considered a very disturbed criminal and not a brilliant scientist. Besides, humans usually only have one child at a time, which makes it really difficult to generate numbers of offspring that can achieve statistical significance. On top of all this, there\'s the issue of genetic manipulation. Key genetic techniques, like mutation screening and transgenics, are completely off-limits to human geneticists. Drosophila melanogaster (Fruit fly) would be better suited as a model organism for genetics experiments. 1. The relationship between fruit fly and human genes is so close that often the sequences of newly discovered human genes, including disease genes, can be matched with equivalent genes in the fly. 2. 75 per cent of the genes that cause disease in humans are also found in the fruit fly. 3. Drosophila have a short, simple reproduction cycle. It is normally about 8-14 days, depending on the environmental temperature. This means that several generations can be observed in a matter of months. 4. Fruit fly are small (3 mm long) but not so small that they can’t be seen without a microscope. This allows scientists to keep millions of them in the laboratory at a time. 5. They are inexpensive to maintain in the laboratory. 6. They require a simple diet consisting of simple sources of carbohydrates (cornmeal) and proteins (yeast extract). 7. The only care they need is having their food changed regularly (every 10-14 days at 25C or 5- 6 weeks at 18C). 8. Drosophila have ‘polytene’ chromosomes, which means that they are oversized and have barcode-like banding patterns.

Menders experiments were conducted using garden peas. Why would human.pdf

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List or describe one feature that represents convergent evolution that is common for the listed set of groups of organisms 1) Brown algae, Chlorophyta, Plants, Animals, and Fungi 2) Gymnamoeba and Radiolarians 3) Gymnamoeba, Euglenoids, Ciliates 4) Euglenoids, Diatoms, Chlorophyta Solution answer = Feature that represent s convergent evolution is common for 1] brown algae ,chorophyta,plants ,animals ,& fungi all are multicelllular 2] Gymnamoeba & Radiolarians Gymnamoeba =Are unicellular protists are ubiquitous in soil & fresh water & marine water are heterotrophs feed on detritious food Radiolarians = are protozoa.

List or describe one feature that represents convergent evolution th.pdf

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Integral membrane proteins that exhibit an intrinsic activity of hydrolyzing ATP to ADP and Pi most likely participate in Question 6 options: A. binding polypeptide hormones. B. generating intracellular messengers during signal transduction. C. initiating one or more steps in blood coagulation. D. moving cations against their concentration gradient. E. targeting proteins to different organelles. Solution Answer:.

Integral membrane proteins that exhibit an intrinsic activity of hyd.pdf

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