This document discusses the role of diet in coronary heart disease (CHD). It identifies major modifiable risk factors for CHD like diabetes, obesity, elevated cholesterol, and homocysteinemia that can be influenced by diet. It provides dietary recommendations for individuals with CHD risk factors or existing CHD, focusing on limiting saturated fats, cholesterol and refined carbohydrates while emphasizing plant-based foods, fiber and antioxidants. The document also describes reversal diets for CHD that restrict animal products and emphasize polyunsaturated and monounsaturated fats to potentially reverse the effects of CHD.
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How Diet Impacts Coronary Heart Disease Risk and Reversal
1. DIET AND CORONARY HEART
DISEASE
DR.HARIVANSH CHOPRA
PROFESSOR & EX. HOD
COMMUNITY MEDICINE
LLRM MEDICAL
COLLEGE,MEERUT
harichop@gmail.com
8/20/2020 1
2. OBJECTIVES :
• To study the risk factors
of CHD.
• To know about the
effect of various dietary
components on CHD.
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3. OBJECTIVES :
• To find out which type
of diet is good in CHD
and in CHD with other
risk factors.
• Lastly, to know how
the effects of CHD
can be reversed.
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4. RISK FACTORS OF CORONARY
HEART DISEASE
Risk Factors:
Modifiable Non Modifiable
Major Minor
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6. Non Modifiable Risk Factors
Age
Sex
Family History
Genetic Factors
Personality
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7. Of these, four factors require
dietary modifications –
Diabetes
Obesity
Elevated Cholesterol
Homocysteinemia
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8. DIABETES MELLITUS:
o Symptoms of diabetes + random
blood glucose > 200mg/dl or
o Fasting blood glucose > 126mg/dl
or
o 2 hr plasma glucose > 200mg/dl
during oral glucose tolerance test.
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9. HYPERCHOLESTEROLEMIA
Desirable levels of serum cholesterol -
<150mg/dl.
When the levels are more
than 250mg/dl –
hypercholesterolemia.
(desired levels of LDL cholesterol -
<100 mg/dl.).
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11. Hypercholesterolemia
Genetic Dietary
Non – modifiable by
diet Alone. Need other
methods like yoga,
exercise, meditation,
statins , plasmapheresis
PCSK9 INHIBITORS
Modifiable by
diet
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Metabolic
12. OBESITY :
Defined as an abnormal
growth of the adipose
tissue due to an
enlargement of the fat
cell size or an increase in
fat cell number or a
combination of both.
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13. According to BMI :
Underweight <18.5
Normal 18.5 – 24.9
Overweight > 25.0
Preobese 25-29.9
Obese class 1 30-34.9
Obese class II 35-39.9
Obese class III > 40.0
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14. HOMOCYSTEINEMIA :
Refers to increased total
plasma concentration of
homocysteine in the
sulfhydryl and disulfide
group,free and protein
bound.
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15. FAMILY HISTORY :
Defined as the presence of the
health condition under consideration
in one’s siblings or parents or
grand – parents < 60 years old. Usually
genetically determined.
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16. ROLE OF DIET IN
HEALTH AND
CORONARY HEART DISEASE
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17. Lets see how much energy is required for
various activities !
Sleep 0.6 cal/min.
Reading 1.4 cal/min.
Eating 1.8 cal/min.
Converse 1.8 cal/min.
Writing 1.9 cal/min.
Standing 2.2 cal/min.
Casual walking 4-5 cal/min.
Running 10-12 cal/min.8/20/2020 17
18. • This energy requirement for the
different activities a person does
in a day can be provided by a
balanced diet in a normal
healthy individual.
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19. BALANCED DIET :
This is the
recommended diet
in a normal
healthy individual
without any risk
factors for
Coronary heart
disease.8/20/2020 19
20. WHAT IS IT ?
15%-20% Proteins
20%-30% Fats
Rest Carbohydrates .
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40. BEVERAGES :
More intake of coffee leads
to –
•Raised serum cholesterol
•Irregular heart beats
Consumers of real boiled
coffee face higher risk.
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41. ALCOHOL :(controversial role)
Increases HDL cholesterol (HDL3
but not HDL2) in marathon
runners and inactive men but not
in men who run and jog.
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42. Daily consumption of one
or two pegs of whisky
or 1-2 glasses of beer
not harmful but beneficial
to heart patients. ????
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43. WATER :
•CVS mortality 10% higher
in areas with very soft water
as compared to medium
hard water.
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44. •In areas where water supply
changed in the last 30 years
favorable effect seen when
water became harder and
unfavorable when it became
softer.
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45. MINERALS :
•Silicon deficiency – atherosclerosis
•Cadmium – toxic to heart
•Low Selenium associated with CHD
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46. ROLE OF FREE RADICALS:
•By-product of oxidation.
•Damage cell membranes, disturb
chromosomes and genetic material
and destroy valuable enzymes.
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47. • Cause 50% of CHD, lung diseases
certain cancers, cataracts, rheumatoid
arthritis, Parkinson’s disease etc.
• 2 ways to reduce them –
1. Less consumption
2. Anti-oxidants.
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48. Anti-oxidants
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sulphur compounds – leeks, onions and garlic
anthocyanins – eggplant, grapes and berries
beta-carotene – pumpkin, mangoes, apricots, carrots,
spinach and parsley
catechins – red wine and tea
49. Anti-oxidants
8/20/2020 49
copper – seafood, lean meat, milk and nuts
cryptoxanthins – red capsicum, pumpkin and
mangoes
flavonoids – tea, green tea, citrus fruits, red wine,
onion and apples
indoles – cruciferous vegetables such as broccoli,
cabbage and cauliflower
50. Anti-oxidants
8/20/2020 50
isoflavonoids – soybeans, tofu, lentils, peas and
milk
lignans – sesame seeds, bran, whole grains and
vegetables
lutein – green, leafy vegetables like spinach, and
corn
lycopene – tomatoes, pink grapefruit and
watermelon
51. Anti-oxidants
8/20/2020 51
manganese – seafood, lean meat, milk and
nuts
polyphenols – thyme and oregano
selenium – seafood, offal, lean meat and
whole grains
vitamin A – liver, sweet potatoes, carrots,
milk, and egg yolks
52. Anti-oxidants
8/20/2020 52
vitamin C – oranges, blackcurrants, kiwifruit, mangoes,
broccoli, spinach, capsicum and strawberries
vitamin E – vegetable oils (such as wheatgerm oil),
avocados, nuts, seeds and whole grains
zinc – seafood, lean meat, milk and nuts
zoochemicals – red meat, offal and fish.
53. So, diets suggested when one
or more risk factors present
but no history of CHD are -
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54. Presence of Hypertension or Family History:
Fats 20-30%
Saturated fats <10%
Dietary cholesterol <300mg/1000kcal/day
Increased consumption of complex carbohydrates
Salt intake <5g/day.
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55. Presence of Hypercholesterolemia
• A two step diet is suggested.
• The goal is to reduce the total
cholesterol to less than 150mg%
and LDL cholesterol to less than
100mg%.
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56. • If after a trial period of 2-
6 months, the Step I diet
fails to lower the
cholesterol then one
should switch to the Step
II diet.
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57. Two step dietary therapy –
Step one –
Fats <30%
Saturated fats <10%
Dietary cholesterol <300mg/day.
PUFA up to 10%
MUFA 10-15%
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81. In persons already suffering
from CHD, right kind of
dietary management will
By pass the need for
interventions and bypass
surgery.
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82. 82
Avoid alcohol
Be physically active
Cut down on salt and sugar
Don’t use tobacco products
Eat plenty of fruits and vegetables
Being healthy is as easy as ABCDE