1. Giant Molluscum
Contagiosum
F. Peral Rubio, M.D.
Department of Dermatology
Hospital Universitario Virgen Macarena,
Seville, Spain

2. Giant Molluscum
Contagiosum
 A 25-years-old woman.
 The patient was referred to us for
the assessment of a pigmented
lesion on the cheek 3 months
previously.
 Examination revealed a single firm,
nontender, and 1.2 x 1.5 cm
nodule.

5. Giant Molluscum
Contagiosum
 Histopathology showed epithelial
hyperplasia and many epidermal cells
contained large intracytoplasmic
inclusion bodies

6. Giant Molluscum
Contagiosum
 Molluscum contagiosum is a common
skin infection caused by DNA poxvirus.
 It spreads by both sexual and nonsexual
route like direct contact with infected skin
or fomites.
 After an average incubation period of
two to three months, flesh colored, dome
shaped, 3-5 mm sized papules with
central umbilication appear on the face,
trunk and exposed body parts.

7. Giant Molluscum
Contagiosum
 Usually has a size that is between 2
and 4 mm in diameter, are uncommon
be larger than 1 cm in diameter.
 In these cases, the molluscum
contagiosum may resemble a number
of other disorders, such as this
patient.

8. Giant Molluscum
Contagiosum
F. Peral Rubio, M.D.
Department of Dermatology
Hospital Universitario Virgen Macarena,
Seville, Spain