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Genetics, DNA, and Heredity
What is DNA?

DNA - DeoxyriboNucleic Acid
 Long molecule used in storing hereditary
 (genetic) information makes up genes.
    - “blueprints” that build an organism.
Gene

Gene – small piece (segment) of DNA that
 codes for a specific trait.
              - Trait - eye color, hair color,
                           height, etc.
Where are Genes?
Genes pass on hereditary material to offspring.

Asexual reproduction – all genes come from one
  parent (mitosis).
     - Offspring identical to parent.

Sexual reproduction – half genes from mom and
  half from dad (meiosis).
      - Offspring are different from parent.
Structure of DNA

DNA is made up of thousands of smaller
  molecules called nitrogenous bases.
4 Kinds of Nitrogenous Bases

a.   Adenine    (A)
b.   Guanine    (G)
c.   Cytosine   (C)
d.   Thymine     (T)

These 4 bases exist in pairs:
Guanine-Cytosine (G-C) and Adenine-Thymine (A-T)
     (Good Couples are Always Together)
Shape of DNA

Double Helix – looks like a twisted
ladder with two strands of DNA wrapped
around each other.
The “Ladder” (Draw Me!)
            Nitrogenous bases form
            the “steps” of the ladder
“Packaging” DNA

     The nucleus contains the
      chromosomes.
     Chromosomes contain
      lots of DNA strands
      which make up genes.
DNA Replication

     Before a cell divides
     (mitosis or meiosis) it
     must replicate, or copy,
     its DNA.
          - This makes sure that
     all cells have copies of the
     DNA.
How is DNA Replicated?

DNA is replicated in 3 steps:
ïŹ Original DNA molecule unzips
ïŹ 2 new strands begin to take form
ïŹ Two identical DNA strands are formed
1. Unzip original DNA

Original DNA molecule becomes separated
  (unzips).
2. Expand Two New Strands

Each original strand now becomes a
 template (model) for a new strand of
 DNA.
Base pairs are added to new strand using the
same rules Good Couples Always Together.

                          Original New
                          A       T
                          T       A
                          T       A
                          G       C


    New Strand
3. Two Identical DNA Molecules are Formed


    Two new DNA molecules formed, each with 1
     original strand and 1 new strand.
Heredity and Traits

Proteins decide which
  traits will be shown
  by the offspring.
DNA codes for which
  amino acids will
  make the proteins.
What Organelle Makes Proteins?

The organelles that
  assemble proteins
  from amino acids are
  the ribosomes.
How Does DNA’s Directions Get to
        the Ribosomes?

1.   A messenger molecule (RNA) copies
     information from the DNA.
2.   The messenger molecule (RNA) goes to
     the ribosome.
3.   The ribosome collects amino acids and
     assembles the proteins in the proper
     order.
Changes in Heredity- Mutations
Nothing is perfect


Mutation – any changes (alterations) in the
  sequence of DNA that affects genetic
  information and the appearance of offspring.
Types of Mutations

Gene mutation – a mutation that occurs in a
 single gene and affects one trait.
     Ex: Eye color, Sickle cell Anemia,
 Hemophilia


Chromosome mutation – a mutation that occurs
 in many genes and affects many traits at once.
     Ex: Down Syndrome (an extra 21st
 chromosome)
How Can Mutations Affect an
             Organism?

Body cell mutations can cause cancer.
   - only the individual is affected.
Gamete cell mutations affect the egg and the sperm.
   - all offspring of the individual can be affected.

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Dna

  • 2. What is DNA? DNA - DeoxyriboNucleic Acid Long molecule used in storing hereditary (genetic) information makes up genes. - “blueprints” that build an organism.
  • 3. Gene Gene – small piece (segment) of DNA that codes for a specific trait. - Trait - eye color, hair color, height, etc.
  • 5. Genes pass on hereditary material to offspring. Asexual reproduction – all genes come from one parent (mitosis). - Offspring identical to parent. Sexual reproduction – half genes from mom and half from dad (meiosis). - Offspring are different from parent.
  • 6. Structure of DNA DNA is made up of thousands of smaller molecules called nitrogenous bases.
  • 7. 4 Kinds of Nitrogenous Bases a. Adenine (A) b. Guanine (G) c. Cytosine (C) d. Thymine (T) These 4 bases exist in pairs: Guanine-Cytosine (G-C) and Adenine-Thymine (A-T) (Good Couples are Always Together)
  • 8. Shape of DNA Double Helix – looks like a twisted ladder with two strands of DNA wrapped around each other.
  • 9. The “Ladder” (Draw Me!) Nitrogenous bases form the “steps” of the ladder
  • 10. “Packaging” DNA The nucleus contains the chromosomes. Chromosomes contain lots of DNA strands which make up genes.
  • 11. DNA Replication Before a cell divides (mitosis or meiosis) it must replicate, or copy, its DNA. - This makes sure that all cells have copies of the DNA.
  • 12. How is DNA Replicated? DNA is replicated in 3 steps: ïŹ Original DNA molecule unzips ïŹ 2 new strands begin to take form ïŹ Two identical DNA strands are formed
  • 13. 1. Unzip original DNA Original DNA molecule becomes separated (unzips).
  • 14. 2. Expand Two New Strands Each original strand now becomes a template (model) for a new strand of DNA.
  • 15. Base pairs are added to new strand using the same rules Good Couples Always Together. Original New A T T A T A G C New Strand
  • 16. 3. Two Identical DNA Molecules are Formed Two new DNA molecules formed, each with 1 original strand and 1 new strand.
  • 17. Heredity and Traits Proteins decide which traits will be shown by the offspring. DNA codes for which amino acids will make the proteins.
  • 18. What Organelle Makes Proteins? The organelles that assemble proteins from amino acids are the ribosomes.
  • 19. How Does DNA’s Directions Get to the Ribosomes? 1. A messenger molecule (RNA) copies information from the DNA. 2. The messenger molecule (RNA) goes to the ribosome. 3. The ribosome collects amino acids and assembles the proteins in the proper order.
  • 20. Changes in Heredity- Mutations
  • 21. Nothing is perfect
 Mutation – any changes (alterations) in the sequence of DNA that affects genetic information and the appearance of offspring.
  • 22. Types of Mutations Gene mutation – a mutation that occurs in a single gene and affects one trait. Ex: Eye color, Sickle cell Anemia, Hemophilia Chromosome mutation – a mutation that occurs in many genes and affects many traits at once. Ex: Down Syndrome (an extra 21st chromosome)
  • 23. How Can Mutations Affect an Organism? Body cell mutations can cause cancer. - only the individual is affected. Gamete cell mutations affect the egg and the sperm. - all offspring of the individual can be affected.