1. SCROTAL DOPPLER
Dr. Pradeep Patil
Professor Dept of Radiodiagnosis
DY Patil Medical college and Hospital
Kolphapur
2. Arterial supply of testis
ā¢ Testicular artery arises from -- aorta
ā¢ Extends directly to the testicle and epididymis, following the course of the spermatic cord and the
body of the epididymis.
ā¢ Structures other than the testicle and epididymis receive arterial supply from
ļ¼ cremasteric artery ā origin from inferior epigastric
ļ¼ deferential branches ā origin from internal iliac arteries
ā¢ Although the testicular arteries provide the principal arterial supply to the testicle and epididymis,
anastomotic channels exist among all of the scrotal arteries, permitting collateral flow.
3.
4. ā¢ The testicular (or spermatic) artery follows the course of the epididymal body through the
mediastinum testis
ā¢ Then gives off capsular branches that circle the periphery of the testicle, beneath the tunica
albuginea.
ā¢ The capsular arteries give off centripetal arteries that course through the testicle toward the
mediastinum and then loop back for a short distance as the recurrent rami.
ā¢ The venous drainage parallels the arterial distribution.
5. ā¢ The venous drainage of each testicle and epididymis is via a network of tiny veins called the
pampiniform plexus.
ā¢ This network gradually coalesces to form two or three veins that follow the spermatic cord and unite
as the spermatic (testicular) vein.
ā¢ On the left, the spermatic vein drains into the ipsilateral renal vein
ā¢ On the right, the spermatic vein drains into the inferior vena cava.
6.
7. Normal colour and spectral doppler of testis
Spectral Doppler
ļ¼Arterial flow to the testicle and
epididymis -exhibits a low-
resistance pattern with continuous
flow during diastole
ļ¼In contrast, a high-resistance blood
flow pattern is seen in
extragonadal arteries example-
cremasteric system.
ā¢ These arteries are occasionally visualized along the
course of the spermatic cord.
ā¢ It is important not to mistake extragonadal Doppler flow
signals for testicular flow
Color Doppler
ļ¼Postpubertal boys and adults,
blood are seen within and at the
periphery of the testicle.
8. ā¢ Peak systolic velocity in testicular arteries ranges from 4 to 19 cm/s (mean 9.7 cm/s).
ā¢ End-diastolic velocity ranges from 1.6 to 6.9 cm/s (mean 3.6 cm/s).
Prerequisite for quantitative assesment
ļ¼ Sufficiently long arterial segment should be visualized with color doppler imaging
allowing for angle correction of the doppler signal.
ļ¼ When angle correction is not possible, spectral doppler features are evaluated qualitatively.
Uses of quantitative assesment
ā¢ Assessment of arterial pulsatility patterns
ā¢ Measurement of blood flow velocities and velocity ratios
ā¢ Comparison of testicular blood flow from one side to the other quantitatively.
9.
10. Sonographic technique
TRANSDUCER
ā¢ A linear-array transducer with a frequency of10 MHz or higher is used.
ā¢ A lower frequency setting may be needed if the scrotum is severely swollen.
COLOUR DOPPLER SETTINGS
ā¢ Color velocity scale must be set to a low setting to detect very low velocity blood flow signals.
ā¢ A relatively high color Doppler gain setting is needed.
ā¢ Use an appropriate spectral display scale to maximize the size of the doppler waveform
display.
ā¢ One method to improve the visualization of blood flow signals is to increase the color Doppler gain until artifacts appear in the
image and then decrease the gain slightly
11. ā¢ In some normal individuals, one or more large artery/vein pair(s) may
traverse the testicle obliquely from the mediastinum.
ā¢ These transmediastinal vessels may be visible on gray-scale imaging and
should not be mistaken for pathology.
12. Epididymitis and orchitis
ā¢ Infection is the most common cause of acute scrotal pain and tenderness
ā¢ Most common cause - infection caused by sexually transmitted organisms (principally Neisseria gonorrhoeae
and Chlamydia trachomatis)
ā¢ They ascend through the genital tract
tail of the epididymis
infection spreads throughout the epididymis (epididymitis).
testicle (epididymo-orchitis)
scrotal cavity, generating an infected hydrocele
13. Ultrasound features
ā¢ Enlargement of involved structures.
ā¢ Decreased echogenicity of the affected structures.
ā¢ Increased blood flow (hyperemia) on color or power doppler
examination.
ā¢ A hydrocele (excess scrotal fluid) is often present
ā¢ Scrotal wall may become edematous and/ or inflamed.
14.
15.
16. ā¢ In some cases findings are less obvious and are based solely on side-
to-side comparison of epididymal size, echogenicity, and blood flow
patterns.
ā¢ Obviously, side-by-side comparison is not helpful in cases of
symmetrical, bilateral infection; nevertheless, hyperemia of the
scrotal contents may still be evident in such cases.
.
17.
18. Focal orchitis-
ā¢ It is noteworthy that focal orchitis may be seen as a focal, hypoechoic
area of inflammation at the periphery of the testicle, adjacent to an
infected epididymal head
ā¢ This should not be mistaken for a testicular tumor but should be
followed to resolution after antibiotic treatment.
19.
20. ā¢ The epididymis and testicle usually return to a normal sonographic
appearance following an episode of infection
ā¢ Complications of epidydimoorchitis-
ļ¼Chronic epididymitis (untreated or incompletely treated cases).
ļ¼Abscesses.
ļ¼Severe cases, testicular atrophy or infarction may occur.
ā¢ Atrophy is a noteworthy complication of mumps orchitis.
21. Chronic epidydimitis
ā¢ Diffuse thickening and heterogeneity of the epididymis
ā¢ Or focal, heterogeneous epididymal mass.
ā¢ Increased blood flow may not be a feature of chronic epididymitis.
ā¢ Hydrocele may also be present, and this may be septated or contain
echogenic material.
22. Epidydimal abscess
ā¢ These appear as complex fluid collections with irregular
walls,sometimes containing diffuse or dependent debris.
ā¢ Increased blood flow caused by hyperemia may be apparent in the
surrounding tissues, either focally or diffusely.
ā¢ If an epididymal abscess becomes chronic, hyperemia may no longer
be evident.
23.
24. Varicocele
ā¢ Common cause of a palpable scrotal mass and pelvic discomfort.
ā¢ In some individuals, a varicocele contributes to low sperm count,
decreased sperm motility, and infertility.
ā¢ These problems have been attributed to persistent hyperemia-
induced elevation of testicular temperature
25. ā¢ The veins of the pampiniform plexus, which drain the testicle and
epididymis, are normally quite small, but these may dilate and
become tortuous forming a tangle of enlarged veins along the course
of the spermatic cord and epididymis
Causes-
ā¢ Valvular incompetence
ā¢ Elevated venous pressure
26. Why are varicoceles MC on left?
ā¢ Varicoceles are more common on the left side of the scrotum than
the right because of elevated pressure in the left spermatic vein.
Cause-
ā¢ The left spermatic (testicular) vein inserts into the left renal vein, which drapes across the aorta
and may be compressed between the aorta and superior mesenteric artery, raising venous
pressure.
ā¢ Higher hydrostatic pressure than the right because of its longer course.
ļ¼Spermatic vein obstruction as a result of an intra-abdominal mass should be considered
whenever an isolated right scrotal varicocele is diagnosed.
27. Diagnosis
ā¢ Color doppler ultrasound when numerous veins of unusually large
size(>3mm) are seen along the spermatic cord or epididymis.
ā¢ The extent of the varicosities should be documented, and the largest
veins should be measured.
ā¢ The presence of reflux within the veins can be investigated by having
the patient perform the valsalva maneuver during color doppler
imaging.(The demonstration of reflux in the veins during a Valsalva maneuver is further evidence of potential clinical
significance of a varicocele)
28. Grading of varicocele
ā¢ grade I: reflux at the level of groin only during the Valsalva maneuver,
ā¢ grade II: reflux at the level of the proximal segment of the
pampiniform plexus only during the Valsalva maneuver
ā¢ grade III: reflux in the distal vessels at the level of lower scrotum only
during the Valsalva maneuver
ā¢ grade IV: spontaneous reverse flow, increasing during the Valsalva
maneuver, with scrotal deformation and possible testicular
hypotrophy.
ā¢ grade V: resting reflux in the dilated pampiniform plexus, possibly
increasing during the Valsalva maneuver, always accompanied by
testicular hypotrophy.
29.
30. Testicular torsion
Definition-
ā¢ Torsion refers to twisting of the testicle within the scrotal sac, such that the
arteries and veins are compressed and blood flow is compromised.
ā¢ Torsion usually occurs in children or young adults, and two peaks of
incidence have been noted: the neonatal period and puberty.
ā¢ Torsion in neonates is typically extravaginal.
ā¢ Torsion during puberty and in young adults is virtually always intravaginal
31. ā¢ Intravaginal torsion-
Where the parietal tunica vaginalis remains intact, while the scrotal
contents inside the parietal tunica twist.
ā¢ Extravaginal torsion-
That is, the entire contents of the scrotum twist on the spermatic cord,
including the parietal and visceral layers of the tunica vaginalis.
32. Bare area of testicle-
ā¢ Normally, the parietal layer of the tunica vaginalis lines the inner wall of the
scrotal sac until it reaches the edge of the testicle, where it reflects over the
testicle, forming the visceral layer of the tunica vaginalis
ā¢ The portion of the testicle that is not covered by the visceral layer of the tunica
vaginalis is closely held against the scrotal wall and called the bare area.
ā¢ Vessels and tubules from the spermatic cord enter and leave the testicle across
the bare area..
ā¢ When the bare area is abnormally small (bell clapper deformity), the attachment
of the testicle to the scrotal wall is narrow and the testicle is at risk of torsion
because of twisting at this attachment.
33. Pathological sequence
Spermatic cord twists, with a rotation of at least 360 degrees, at the bare area.
Venous obstruction- swelling and increased pressure(inside testis and spermatic cord)
Arterial flow becomes occluded
Testicular ischemia results
Progressing to infarction
If detorsion does not occur surgically or spontaneously.
34. ACUTE TORSION- (first 6 to 10hrs)
ļ¼During which the testicle suffers ischemia without permanent injury
if detorsion occurs.
ā¢ MISSED TORSION-(after 24hrs)
ļ¼ The stage after which testicular infarction has occurred to the point
that the testicle cannot be saved even if detorsed
35. ā¢ B- mode and color doppler ultrasound is the imaging method of choice for diagnosing
testicular torsion.
Soon after torsion occurs-
ā¢ Testicle may appear normal in echotexture
ā¢ Spermatic cord and epididymis may appear as a thick echogenic structure with acoustic
shadowing caused by twisting and the knot.
ā¢ On doppler imaging blood flow will appear diminished or absent in the testicle and the
knotted cord and epididymis.
ā¢ If blood flow is still present on the affected side, spectral waveforms typically
demonstrate high-resistance flow(resistive index (RI >0.75)) , compared with the low
resistance flow in the normal testicle
36.
37.
38. As the torsion persists-
ā¢ Testicle becomes enlarged and hypoechoic due to swelling and edema
ā¢ A small hydrocele may be seen.
With color doppler imaging,
ā¢ Blood flow remains diminished or absent in the testicle and
epididymis.
39.
40. If there is further progression-
ā¢ Testicular necrosis occurs.
ā¢ Testicle becomes mottled and heterogeneous with hypoechoic areas.
ā¢ Scrotal wall becomes thickened and hypervascular.
If detorsion of the testicle occurs-
ā¢ In such cases, the affected testicle may be hyperemic compared with the normal
testicle
ā¢ In these cases, the knot of the twisted cord and epididymis will not be present.
ā¢ If the testicle is examined during the hyperemic period, increased blood flow may be mistaken for orchitis.
41.
42. Neonatal or extravaginal torsion-
ļ¼Swelling of the testicle with generalized decreased echogenicity and absence of blood flow in the
affected testicle
ļ¼The swollen testicle and epididymis maintain their anatomic relationship because both the
parietal and visceral layers of the tunica vaginalis have torsed with the testicle.
ā¢ Sometimes, fluid is seen in two spaces surrounding the testicle, an inner
collection within the parietal tunica vaginalis and a rim of fluid outside the
parietal tunica.
46. Testicular cysts
ā¢ Most intratesticular cyst are located near the mediastinum testicle.
ā¢ Cysts located on the testicular surface are almost always tunical cysts,
arising in the tunica albuginea.
47. Sonographic features:-
ļ¼ Anechoic contents.
ļ¼ Sharply defined borders and an invisible wall.
ļ¼ Enhanced through transmission of ultrasound.
ļ¼ No blood flow within or surrounding the cyst (other than normal testicular vessels).
48. Epididymal cysts
ā¢ More common than testicular cysts.
ā¢ Most common location - epididymal head.
ā¢ They may be single, multiple, unilateral, or bilateral.
ā¢ Unlike testicular cysts, epididymal cysts may be septated or even
multilocular and occasionally they may be several centimeters.
ā¢ Have same sonographic features as testicular cysts
ā¢ Epididymal cysts have no solid components, have exquisitely thin walls, and
show no internal blood flow on color doppler examination.
49.
50. Testicular neoplasms
ā¢ Ultrasound can distinguish intratesticular from extratesticular pathology with extremely high
accuracy.
ā¢ Nevertheless, ultrasound generally cannot differentiate between different histologic types of
testicular tumors, nor can it generally differentiate between malignant (common) and benign
(uncommon) neoplasms.
51. B- mode ultrasound features-
ļ¼Most testicular tumors - are well-defined hypoechoic intratesticular
masses
ļ¼Some may be poorly marginated or grossly infiltrating.
ļ¼They may exhibit some degree of internal heterogeneity because of
hemorrhage and/or necrosis, and calcifications are occasionally
present.
52. ā¢ Colour doppler-
ļ¼Internal vascularity is evident within testicular neoplasms on the
color doppler flow examination.
ļ¼Large avascular areas may be present in a testicular tumor when
necrosis or hemorrhage is present.
ļ¼Most malignant tumors are hypervascular.
53. Spectral doppler ā
ļ¼Shows low-resistance blood flow within tumor vessels, a typical
finding seen in malignant neoplasms .
ļ¼Blood flow velocities may be substantially elevated in markedly
hypervascular tumors.
54.
55.
56. Mimics of neoplasms
ļ¼Inflamed areas (without frank abscess formation)- focal orchitis
ļ¼Infarcts
ļ¼Abscesses
ļ¼Contusions
ļ¼Hematomas
ā¢ Color and spectral doppler features are of considerable importance in
differentiating these etiologies.
ā¢ No flow is present in abscesses, infarcts, and hematomas,but
hypervascularity may be present in the periphery of these lesions.
57. Focal testicular infarction
ā¢ Causes
ļ¼Trauma(testicular contusion or testicular fracture compromising blood
flow)
ļ¼Infection
ļ¼Vascular compromise(vasculitis or other causes of vascular compromise)
ā¢ Infarction following an infection(compromised blood flow - secondary to edema compressing
venous flow)
ā¢ The affected area is usually at the periphery of the testicle near the epididymal head or tail,
common sites of focal orchitis.
58. On ultrasound and doppler examinations,
ļ¼The infarct may appear as a discrete, wedge-shaped or round testicular
lesion that is heterogeneous and hypoechoic.
ļ¼Little or no blood flow on color doppler imaging
ļ¼The surrounding parenchyma may appear normal.
ļ¼The infarct may contain cystic areas if necrosis has occurred.
ā¢ In some cases, a testicular infarct may be indistinguishable from a testicular
tumor and the diagnosis is only made at pathology after orchiectomy
If an infarct is suspected on the basis of the patientās history, age, and sonographic appearance, close
sonographic and Doppler follow-up is indicated, to be certain the lesion decreases in size with time, proving
that it is not a tumor.
Editor's Notes
Doppler image shows the capsular artery (arrows) and intraparenchymal vessels.
Low-resistance Doppler waveforms of normal testicular flow
Enlargement and hypervascularity of the epididymal tail (arrows), representing epididymitis of the tail
enlarged and hypervascular epididymal body (arrows) secondary to epididymitis.
right testicle and epididymal head and body (calipers), demonstrating marked thickening of the epididymal body caused by epididymo-orchitis
colorDoppler image showing hypervascularity of a portion of the epididymal body (arrow) and hypervascularity throughout the testicle
Transverse image of both testicles side by side, showing enlargement of the right (R) testis
Transverse color Doppler image of both testicles shows marked hypervascularity on the right (R) compared with the normal vascularity on the left
hypoechoic ill-defined area involving lower polar region with increased vascularity.
The head of the left epididymis is enlarged, heterogeneously hypoechoic with echogenic foci. Markedly hyperemic margins of the epididymis head
the center is anechoic/ hypoechoic with fluid leveling, and completely avascular on color doppler interrogation.
Dilated and tortuous serpenginous veins with >3 mm diameter and showing reflux on valsalva
The rightĀ testisĀ is enlarged. It shows a normal echo pattern without a mass lesion
Its parenchymal is reduced suggested with increased RI value.
There are a twistedĀ spermatic cordĀ showing concentric pattern on the grayscale as well as with color doppler scan.
Transverse view of right torsed testicle demonstrates swelling of the testicle with geographic areas of decreased echogenicity.
A small hydrocele is present. Part of the knot of the twisted cord and epididymis is seenadjacent to the testicle.
Transverse color Doppler image demonstrating flow in the normal left testicle and almost no flow in the right testicle because of torsion.
Left testis:Ā oedematous, heterogeneous echopattern, no flow on color Doppler imaging.
Twist of left spermatic cord is noted.
One day old baby
The right testicle is enlargedĀ with a parenchyma diffusely heterogeneous showing internal hypoechoic areas of necrosis, an absence of flow on Doppler and a small septated hydrocele
located immediately adjacent to the echogenic mediastinum testis
Doppler image of testicle and epididymis showing an anechoic cyst (arrow) with no internal flow in the head of the epididymis
epididymal body posterior to the testicle and containing a simple cyst
A well-defined lobulated hypoechoic eccentric nodule measuring is seen in the left testis. -seminoma
No cystic component or calcifications are seen in it. Color Doppler ultrasound examination shows internal and peripheral vascularity
Heterogenous mass lesion is seen in left testis with areas of cystic changes with minimal internal vascularity
Wedge shaped hupoechoic areas are noted in the left testis with no colour flow and surrounding parenchyma appears normal
another patient showing hetrogenously hypoechic region with regional absence of blood flow in the upper pole of the testicle, an area of focal infarction.
Hypoechoic areas with multiple small cytic areas within it are noted with absent blood flow