Since it was approved to treat a variety of conditions in 1989, BOTOX® has become the most frequently administered cosmetic treatment in the United States. BOTOX® is most commonly used to smooth wrinkles on the forehead, around the eyes, and around the mouth. BOTOX® works by putting a barrier between the nerves and muscles, blocking the signals that cause contraction. This in turn leads to a relaxation and softening of wrinkles. It only take a few moments to complete a BOTOX® treatment, and it requires no anesthesia. The effects last anywhere from four to six months. With repeated treatments, wrinkles return with increasingly less severity as the muscles learn to stay relaxed. About Dr. Stefan Kieserman Stefan Kieserman, MD, received his medical degree from the Albert Einstein College of Medicine at Yeshiva University. He has been practicing cosmetic surgery in New York City since 1996.