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What should be the approach when
laparoscopic sleeve gastrectomy fails
to reduce the weight?
A review of literature
Dr. Abdul Qadeer Memon
MBBS; FCPS; FICS
Assistant Professor in Surgery
& Consultant General Surgeon
King Faisal University College of Medicine
Kingdom of Saudi Arabia
Obesity
■ Metabolic disorder
■ Associated with:
Diabetes mellitus
Hypertension
Heart diseases
Infertility
Cancer
Anti-obesity drugs
■ Amphetamine based drugs
■ Appetite suppressors
■ Block cannabinoid receptors
■ Examples: Orlistat (Xanical),
Rimonabant (Acomplia),
Sibutramine (Meridia)
■ Not promising effect
■ Side effects
Anti-obesity surgery
Restrictive
■ Gastric banding
■ Sleeve gastrectomy
■ Roux-en-Y gastric
bypass
Malabsorptive
■ Bilio-pancreatic
diversion
■ Duodenal switch
■ None of the surgical procedure is without
complications
■ Newer techniques:
NOTES
Single incision technique
Transoral gastroplasty (TOGA)
Primary obesity surgery endoluminal (POSE)
Endobarrier
Methodology
■ Online search of Pubmed
■ Abstracts & full articles to find the most suitable
revision procedure after failed LSG
■ Seven studies, which included 296 cases,
selected online were reviewed
Criterion for failure
■ Insufficient weight loss or
■ Weight regain
■ Criteria are:
Bariatric Analysis and Reporting Outcome
System (BAROS)
Reinhold criteria (>25% EWL)
%EWL at
24 months
%EWL at
18 months
%EWL at
12 months
%EWL at
6 months
%EWL at
3 months
ProcedureName of study
48
44
75
58
48
NA
60
68
65
37
48
NA
27
50
NA
LGBP*
LReSG*
OSI*
Cheung D et al
(n=218)
51.6±14.848.6±2149.3±19.837.2±12.426.8±12LMGBP-OL*
(%EBL*)
Moszkowicz D et
al (n=19)
NANA56.8±12.4NANALReSG*Giovanni C et al
(n=11)
NANA29.1NANALReSG*Rebibo et al
(n=15)
61.7NANANANARYGBP*Gautier T et al
(n=9)
28NANANANARYGBP*Langer FB et al
(n=5)
80±40
65.5±34
NANANANABPD-DS*
RYGBP*
Carmeli I et al
(n=19)
LGBP = Laparscopic gastric bypass, LReSG = Laparoscopic re-sleeve gastrectomy RYGBP = Roux-en-Y
gastric bypass, LMGBP-OL = Laparoscopic mini-gasric bypass-Omega loop, BPD-DS = Bilio-pancreatic
diversion-Duodenal switch,
0
10
20
30
40
50
60
70
80
12345
Cheung D et al
(n=218)
LGBP* LReSG* OSI*
Study by Prof. Hamed A. Al-Wadaani
■ Mini-gastrectomy with bypass has been conducted by Prof. Dr. Hamed A. Al-
Wadaani
■ It is about to be published
■ 23 patients have been operated so far
■ 85% EWL has been reduced
■ Negligible complications
Conclusion
■ None of the procedures is without complications
■ Selection of the procedure may very according to the patients
■ Re-sleeve gastrectomy is good option for dilated stomach pouch
■ Gastric bypass is better choice in failure of sleeve gastrectomy without dilatation
of stomach for selective patients
■ Mini-gastrectomy with by-pass is the better choice for re-do surgery with
promising results of 85% EWL and negligible complications
■ Weight loss is significant in BPD-DS if the patient is strictly compliant of post-
operative instructions to have micronutrients, vitamins and excessive proteins;
otherwise can be fatal

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Dr. Abdul Qadeer Memon

  • 1. What should be the approach when laparoscopic sleeve gastrectomy fails to reduce the weight? A review of literature Dr. Abdul Qadeer Memon MBBS; FCPS; FICS Assistant Professor in Surgery & Consultant General Surgeon King Faisal University College of Medicine Kingdom of Saudi Arabia
  • 2. Obesity ■ Metabolic disorder ■ Associated with: Diabetes mellitus Hypertension Heart diseases Infertility Cancer
  • 3. Anti-obesity drugs ■ Amphetamine based drugs ■ Appetite suppressors ■ Block cannabinoid receptors ■ Examples: Orlistat (Xanical), Rimonabant (Acomplia), Sibutramine (Meridia) ■ Not promising effect ■ Side effects
  • 4. Anti-obesity surgery Restrictive ■ Gastric banding ■ Sleeve gastrectomy ■ Roux-en-Y gastric bypass Malabsorptive ■ Bilio-pancreatic diversion ■ Duodenal switch
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10. ■ None of the surgical procedure is without complications ■ Newer techniques: NOTES Single incision technique Transoral gastroplasty (TOGA) Primary obesity surgery endoluminal (POSE) Endobarrier
  • 11. Methodology ■ Online search of Pubmed ■ Abstracts & full articles to find the most suitable revision procedure after failed LSG ■ Seven studies, which included 296 cases, selected online were reviewed
  • 12. Criterion for failure ■ Insufficient weight loss or ■ Weight regain ■ Criteria are: Bariatric Analysis and Reporting Outcome System (BAROS) Reinhold criteria (>25% EWL)
  • 13.
  • 14. %EWL at 24 months %EWL at 18 months %EWL at 12 months %EWL at 6 months %EWL at 3 months ProcedureName of study 48 44 75 58 48 NA 60 68 65 37 48 NA 27 50 NA LGBP* LReSG* OSI* Cheung D et al (n=218) 51.6±14.848.6±2149.3±19.837.2±12.426.8±12LMGBP-OL* (%EBL*) Moszkowicz D et al (n=19) NANA56.8±12.4NANALReSG*Giovanni C et al (n=11) NANA29.1NANALReSG*Rebibo et al (n=15) 61.7NANANANARYGBP*Gautier T et al (n=9) 28NANANANARYGBP*Langer FB et al (n=5) 80±40 65.5±34 NANANANABPD-DS* RYGBP* Carmeli I et al (n=19) LGBP = Laparscopic gastric bypass, LReSG = Laparoscopic re-sleeve gastrectomy RYGBP = Roux-en-Y gastric bypass, LMGBP-OL = Laparoscopic mini-gasric bypass-Omega loop, BPD-DS = Bilio-pancreatic diversion-Duodenal switch,
  • 15. 0 10 20 30 40 50 60 70 80 12345 Cheung D et al (n=218) LGBP* LReSG* OSI*
  • 16. Study by Prof. Hamed A. Al-Wadaani ■ Mini-gastrectomy with bypass has been conducted by Prof. Dr. Hamed A. Al- Wadaani ■ It is about to be published ■ 23 patients have been operated so far ■ 85% EWL has been reduced ■ Negligible complications
  • 17. Conclusion ■ None of the procedures is without complications ■ Selection of the procedure may very according to the patients ■ Re-sleeve gastrectomy is good option for dilated stomach pouch ■ Gastric bypass is better choice in failure of sleeve gastrectomy without dilatation of stomach for selective patients ■ Mini-gastrectomy with by-pass is the better choice for re-do surgery with promising results of 85% EWL and negligible complications ■ Weight loss is significant in BPD-DS if the patient is strictly compliant of post- operative instructions to have micronutrients, vitamins and excessive proteins; otherwise can be fatal