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SHORT AND LONG TERM
COMPLICATIONS
FOLLOWING THE
MINI-GASTRIC BYPASS
Robert Rutledge, MD
Centers for Laparoscopic Obesity Surgery
98 E Lake Mead Parkway Suite 302
Henderson NV 89015
Web: www.clos.net, Email: DrR@clos.net
NEED FOR A BETTER FORM OF BARIATRIC SURGERY:
PROBLEMS WITH THE RNY
 A consecutive series of RNY
with a mean follow-up of 11.9 yrs.
 “clinical failure in 36%
Roux stasis syndrome in 27%.”
 One of the longest follow-up to date
 … the RNY appears to be limited by
 …substantial rate of clinical dissatisfaction.
Surgeons should be cautious in using RNY to
treat gastrointestinal disease.
McAlhany JC Jr et al, Long-term follow-up of patients with Roux-en-Y
gastrojejunostomy for gastric disease. Ann Surg. 1994 May;219(5):451-5
MINI-GASTRIC BYPASS
 Studies have demonstrated that MGB is
 Short
 Simple
 Effective
 Reversible and Revisable operation
 With very high levels of patient
satisfaction
MINI-GASTRIC BYPASS REFERENCES
Reference Reference
 Rutledge R. Hospitalization before and
after mini-gastric bypass surgery. Int J
Surg. 2007 Feb;5(1):35-40. Epub 2006
Aug 10.
 Peraglie C. Mini-gastric bypass in a
patient homozygous for Factor V
Leiden. Obes Surg. 2007 Jan;17(1):104-
7.
 Johnson WH, et al. Surgical revision of
loop ("mini") gastric bypass
procedure: multicenter review of
complications and conversions to
Roux-en-Y gastric bypass. Surg Obes
Relat Dis. 2007 Jan-Feb;3(1):37-41.
Epub 2006 Dec 27.
 Noun R, Zeidan S, Safa N. Laparoscopic
latero-lateral jejuno-jejunostomy as a
rescue procedure after complicated
mini-gastric bypass. Obes Surg. 2006
Nov;16(11):1539-41.
 Rutledge R, Dorghazi P, Peralgie C.
Efficacy of estradiol topical patch in
the treatment of symptoms of
depression following mini-gastric
bypass in women. Obes Surg. 2006
Sep;16(9):1221-6.
 Chiu CC, Lee WJ, Wang W, Wei PL,
Huang MT. Prevention of trocar-wound
hernia in laparoscopic bariatric
operations. Obes Surg. 2006
Jul;16(7):913-8.
MINI-GASTRIC BYPASS REFERENCES
References References
 Rutledge R, Walsh TR. Continued
excellent results with the mini-gastric
bypass: six-year study in 2,410
patients. Obes Surg. 2005
Oct;15(9):1304-8.
 Lee WJ, et al. Laparoscopic RNY
versus mini-gastric bypass for the
treatment of morbid obesity: a
prospective randomized controlled
clinical trial. Ann Surg. 2005
Jul;242(1):20-8.
 Garcia-Caballero M, Carbajo M. One
anastomosis gastric bypass: a simple,
safe and efficient surgical procedure
for treating morbid obesity. Nutr
Hosp. 2004 Nov-Dec;19(6):372-5.
 Wang W, Wei PL, Lee YC, Huang MT,
Chiu CC, Lee WJ. Short-term results of
laparoscopic mini-gastric bypass.
Obes Surg. 2005 May;15(5):648-54.
 Copaescu C, Munteanu R, Prala N,
Turcu FM, Dragomirescu C.
[Laparoscopic mini gastric bypass for
the treatment of morbid obesity.
Initial experience] Chirurgia 2004 Nov-
Dec;99(6):529-39.
 Wang W, et al. Laparoscopic mini-
gastric bypass for failed vertical
banded gastroplasty. Obes Surg. 2004
Jun-Jul;14(6):777-82.
MINI-GASTRIC BYPASS REFERENCES
References References
 Rutledge R. The mini-gastric bypass:
experience with the first 1,274 cases.
Obes Surg. 2001 Jun;11(3):276-80.
 Rutledge R. Revision of failed gastric
banding to mini-gastric bypass. Obes
Surg. 2006 Apr;16(4):521-3.
 Rutledge R. Similarity of
Magenstrasse-and-Mill and Mini-
Gastric bypass. Obes Surg. 2003
Apr;13(2):318.
 Fisher BL, Buchwald H, Clark W,
Champion JK, Fox SR, MacDonald KG,
Mason EE, Terry BE, Schauer PR,
Sugerman HJ. Mini-gastric bypass
controversy. Obes Surg. 2001
Dec;11(6):773-7.
OLD ANTRECTOMY AND BILLROTH II
The Billroth II is a gastrojejunostomy favored by m any surgeons. In
selected cases a Braun entero-enterostomy may be added.
MINI-GASTRIC BYPASS
I. Restrictive Component:
• Gastric pouch based upon the
lesser curve, similar to Collis
Gastroplasty/Sleeve
Gastrectomy
• Vagotomy
II. Malabsorptive Component
• Ante-colic Billroth II Loop
Gastrojejunostomy
(6 foot + bypass)
• Bypass length varied with
weight of patient
RNY VS. THE MINI-GASTRIC BYPASS
MINI-GASTRIC BYPASS THOUSANDS OF
PATIENTS COME FROM ALL ACROSS THE NATION
Patients have come from all 50 states and around the world to have the MGB
RESULTS
 From 9/97 to 3/2011, 6,526 patients underwent
MGB at the Centers for Excellence in
Laparoscopic Obesity Surgery hospitals
 Follow-up information was achieved in 98% of
patients at 30 days and in 4,046 patients (62%)
overall,
 The mean follow-up was 21 months (range, 6-96
months).
RESULTS
 There were 85% females with a mean
preoperative age of 39 years (range, 12-81 years).
 After surgery, weight and body mass index
decreased from
 295 lbs and 49.1 kg/m2 to
 171 lbs and 28.5 kg/m2 for a
 Mean weight loss of 124 lbs,
 Ideal body weight of 140 lbs
 Mean excess weight loss of 81%.
80% EXCESS WEIGHT LOSS
Weight loss follows a logarithmic curve for the first year
The combination of Restriction, Vagotomy and Bypass
Malabsorption leads to excellent weight loss
5 YEAR WEIGHT LOSS
5 year weight loss is very durable
OPERATIVE OUTCOMES
 MGB was performed in 6,526 patients.
 Mean Operative time: 38 minutes
 The median length of hospital stay was 1 day.
COMPLICATIONS
 The most common early complications were
minor and included pain, nausea and other
nonspecific complaints.
 There were three deaths within 30 days of
surgery
 Perforate Transverse Colon (9 years ago)
 Post Operative MI (6 years ago, at 3 weeks post op
following otherwise uncomplicated surgery.)
 Leak (1 year ago death from Respiratory failure)
SHORT TERM COMPLICATIONS (< 30 DAYS)
 The overall rate of complications was low at 4.36%.
 Leaks (1.02%)
 Bleeding (0.56%)
 Dyspepsia/Gastritis (0.28%)
 Pneumonia (0.28%)
 Pulmonary Embolus (0.19%)
 Thrush (0.19%)
 DVT (0.19%)
 Pain (0.09%)
 Bad Taste (0.09%)
 Port Site Infection (0.09%)
 Port Site Bleeding (0.09%)
 Other (0.09%)
SHORT TERM COMPLICATIONS (< 30 DAYS)
 Port Site Abscess
 Negative Re-exploration
 Infection (other)
 Major Port Leakage
 Hemorrhoids
 Fever
 Failed Intubation
 Drug reaction
 Profound Dehydration
 C. Diff Infection
 Bowel Injury
 Early Ulcer
 Prolonged Ileus
3 (0.09%)
3 (0.09%)
3 (0.09%)
2 (0.07%)
2 (0.07%)
2 (0.07%)
2 (0.07%)
1 (0.04%)
1 (0.04%)
1 (0.04%)
1 (0.04%)
1 (0.04%)
1 (0.04%)
LONG TERM COMPLICATIONS (15%)
 Fifteen percent of patients had some form of
complication.
 Dyspepsia/Gastritis
 Anemia
 Ulcer
 Diarrhea
 Fainting
 Malnutrition w Revision
 Hypo/Hyper-vitaminosis
 Kidney stones
 Gallbladder
(5.2%),
(3.1%)
(2.4%)
(1.2%)
(1.1%)
(1.1%)
(1.0%)
(1.0%)
(0.9%)
LONG TERM COMPLICATIONS (15%)
 Major Hair Loss (0.8%)
 Persistent Dumping (0.7%)
 Unmanageable Gas (0.6%)
 Malnutrition w/o Revision (0.5%)
 Hernia, Gout, Weight Regain (>20 lbs.), Severe
Hypoglycemia (0.3%)
 Severe Osteoporosis, Drug Withdrawal, Yeast
infection, Lactose Intolerant, Low Estrogen, Bowel
Obstruction (0.2%)
 Constipation, Revision for Bile Reflux, Pain, Drug
Allergy, Heavy Menstruation, Neuropathy,
Hyper/Hypoglycemia, Allergic Reaction and Low
Potassium (0.1%)
BILE REFLUX
 Bariatric Surgeons have raised concerns about
Bile Reflux complications after Mini-Gastric
Bypass
 Recent studies have reported revisions to RNY
for “bile reflux”
 While Dyspepsia and Ulcers were common only 3
required revision for bile reflux
 In this series symptoms of dyspepsia and
marginal ulcers were treated successfully with
Antacid (Prilosec, etc.) therapy
CONCLUSIONS
 Mini-Gastric Bypass
 Short
 Simple
 Low Risk
 Effective
 Reversible and Revisable
 Durable
CONCLUSIONS
 The present series reconfirms that the
Mini-Gastric Bypass:
 Short safe and effective weight loss
therapy.
 This study delineates the spectrum and
frequency of complications after early and
late after the MGB.
CONCLUSIONS
 The most frequent complications late after MGB
are Dyspepsia/Gastritis, Iron Deficiency Anemia
and Marginal Ulcer.
 In most cases these complications responded to
medical therapy.
 This study shows the range of late complications
following the MGB.
FEARS ABOUT “BILE REFLUX”
 Early days of gastric bypass
loop placed adjacent to the
esophagus led to …
 “…bilious vomiting was particularly annoying
and persistent in the first (loop) patients and
resulted in a change of technique to the Roux-en-
Y reconstruction”. (Griffen et al)
 Others reported the need for RNY surgery for
MGB associated “Bile Reflux” (Johnson et al)
CONCLUSIONS: BILE REFLUX REDUX
 The present series demonstrates that,
while the symptoms of dyspepsia and ulcers were
relatively common,
they were routinely treated successfully with
antacids medications (i.e. PPI etc.)
 Surgery was necessary in only 3 patients for
symptomatic “Bile Reflux” symptoms
unresponsive to medical therapy
GIL GERARD "BUCK ROGERS", TV STAR
UNDERWENT MINI-GASTRIC BYPASS SURGERY.
Gil Gil Gil
Gerard Gerard Gerard
“Buck In London Post
Rogers” MGB
(1979- 2005 2006
1981)
180 lbs. 340 lbs. 205 lbs.
http://www.youtube.com/view_play_list?p=7BF29152EEF52939
Steps in Performance of MGB
Gil Gil Gil
Gerard Gerard Gerard

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SHORT AND LONG TERM COMPLICATIONS FOLLOWING THE MINI-GASTRIC BYPASS

  • 1. SHORT AND LONG TERM COMPLICATIONS FOLLOWING THE MINI-GASTRIC BYPASS Robert Rutledge, MD Centers for Laparoscopic Obesity Surgery 98 E Lake Mead Parkway Suite 302 Henderson NV 89015 Web: www.clos.net, Email: DrR@clos.net
  • 2. NEED FOR A BETTER FORM OF BARIATRIC SURGERY: PROBLEMS WITH THE RNY  A consecutive series of RNY with a mean follow-up of 11.9 yrs.  “clinical failure in 36% Roux stasis syndrome in 27%.”  One of the longest follow-up to date  … the RNY appears to be limited by  …substantial rate of clinical dissatisfaction. Surgeons should be cautious in using RNY to treat gastrointestinal disease. McAlhany JC Jr et al, Long-term follow-up of patients with Roux-en-Y gastrojejunostomy for gastric disease. Ann Surg. 1994 May;219(5):451-5
  • 3. MINI-GASTRIC BYPASS  Studies have demonstrated that MGB is  Short  Simple  Effective  Reversible and Revisable operation  With very high levels of patient satisfaction
  • 4. MINI-GASTRIC BYPASS REFERENCES Reference Reference  Rutledge R. Hospitalization before and after mini-gastric bypass surgery. Int J Surg. 2007 Feb;5(1):35-40. Epub 2006 Aug 10.  Peraglie C. Mini-gastric bypass in a patient homozygous for Factor V Leiden. Obes Surg. 2007 Jan;17(1):104- 7.  Johnson WH, et al. Surgical revision of loop ("mini") gastric bypass procedure: multicenter review of complications and conversions to Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2007 Jan-Feb;3(1):37-41. Epub 2006 Dec 27.  Noun R, Zeidan S, Safa N. Laparoscopic latero-lateral jejuno-jejunostomy as a rescue procedure after complicated mini-gastric bypass. Obes Surg. 2006 Nov;16(11):1539-41.  Rutledge R, Dorghazi P, Peralgie C. Efficacy of estradiol topical patch in the treatment of symptoms of depression following mini-gastric bypass in women. Obes Surg. 2006 Sep;16(9):1221-6.  Chiu CC, Lee WJ, Wang W, Wei PL, Huang MT. Prevention of trocar-wound hernia in laparoscopic bariatric operations. Obes Surg. 2006 Jul;16(7):913-8.
  • 5. MINI-GASTRIC BYPASS REFERENCES References References  Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg. 2005 Oct;15(9):1304-8.  Lee WJ, et al. Laparoscopic RNY versus mini-gastric bypass for the treatment of morbid obesity: a prospective randomized controlled clinical trial. Ann Surg. 2005 Jul;242(1):20-8.  Garcia-Caballero M, Carbajo M. One anastomosis gastric bypass: a simple, safe and efficient surgical procedure for treating morbid obesity. Nutr Hosp. 2004 Nov-Dec;19(6):372-5.  Wang W, Wei PL, Lee YC, Huang MT, Chiu CC, Lee WJ. Short-term results of laparoscopic mini-gastric bypass. Obes Surg. 2005 May;15(5):648-54.  Copaescu C, Munteanu R, Prala N, Turcu FM, Dragomirescu C. [Laparoscopic mini gastric bypass for the treatment of morbid obesity. Initial experience] Chirurgia 2004 Nov- Dec;99(6):529-39.  Wang W, et al. Laparoscopic mini- gastric bypass for failed vertical banded gastroplasty. Obes Surg. 2004 Jun-Jul;14(6):777-82.
  • 6. MINI-GASTRIC BYPASS REFERENCES References References  Rutledge R. The mini-gastric bypass: experience with the first 1,274 cases. Obes Surg. 2001 Jun;11(3):276-80.  Rutledge R. Revision of failed gastric banding to mini-gastric bypass. Obes Surg. 2006 Apr;16(4):521-3.  Rutledge R. Similarity of Magenstrasse-and-Mill and Mini- Gastric bypass. Obes Surg. 2003 Apr;13(2):318.  Fisher BL, Buchwald H, Clark W, Champion JK, Fox SR, MacDonald KG, Mason EE, Terry BE, Schauer PR, Sugerman HJ. Mini-gastric bypass controversy. Obes Surg. 2001 Dec;11(6):773-7.
  • 7. OLD ANTRECTOMY AND BILLROTH II The Billroth II is a gastrojejunostomy favored by m any surgeons. In selected cases a Braun entero-enterostomy may be added.
  • 8. MINI-GASTRIC BYPASS I. Restrictive Component: • Gastric pouch based upon the lesser curve, similar to Collis Gastroplasty/Sleeve Gastrectomy • Vagotomy II. Malabsorptive Component • Ante-colic Billroth II Loop Gastrojejunostomy (6 foot + bypass) • Bypass length varied with weight of patient
  • 9. RNY VS. THE MINI-GASTRIC BYPASS
  • 10. MINI-GASTRIC BYPASS THOUSANDS OF PATIENTS COME FROM ALL ACROSS THE NATION Patients have come from all 50 states and around the world to have the MGB
  • 11. RESULTS  From 9/97 to 3/2011, 6,526 patients underwent MGB at the Centers for Excellence in Laparoscopic Obesity Surgery hospitals  Follow-up information was achieved in 98% of patients at 30 days and in 4,046 patients (62%) overall,  The mean follow-up was 21 months (range, 6-96 months).
  • 12. RESULTS  There were 85% females with a mean preoperative age of 39 years (range, 12-81 years).  After surgery, weight and body mass index decreased from  295 lbs and 49.1 kg/m2 to  171 lbs and 28.5 kg/m2 for a  Mean weight loss of 124 lbs,  Ideal body weight of 140 lbs  Mean excess weight loss of 81%.
  • 13. 80% EXCESS WEIGHT LOSS Weight loss follows a logarithmic curve for the first year The combination of Restriction, Vagotomy and Bypass Malabsorption leads to excellent weight loss
  • 14. 5 YEAR WEIGHT LOSS 5 year weight loss is very durable
  • 15. OPERATIVE OUTCOMES  MGB was performed in 6,526 patients.  Mean Operative time: 38 minutes  The median length of hospital stay was 1 day.
  • 16. COMPLICATIONS  The most common early complications were minor and included pain, nausea and other nonspecific complaints.  There were three deaths within 30 days of surgery  Perforate Transverse Colon (9 years ago)  Post Operative MI (6 years ago, at 3 weeks post op following otherwise uncomplicated surgery.)  Leak (1 year ago death from Respiratory failure)
  • 17. SHORT TERM COMPLICATIONS (< 30 DAYS)  The overall rate of complications was low at 4.36%.  Leaks (1.02%)  Bleeding (0.56%)  Dyspepsia/Gastritis (0.28%)  Pneumonia (0.28%)  Pulmonary Embolus (0.19%)  Thrush (0.19%)  DVT (0.19%)  Pain (0.09%)  Bad Taste (0.09%)  Port Site Infection (0.09%)  Port Site Bleeding (0.09%)  Other (0.09%)
  • 18. SHORT TERM COMPLICATIONS (< 30 DAYS)  Port Site Abscess  Negative Re-exploration  Infection (other)  Major Port Leakage  Hemorrhoids  Fever  Failed Intubation  Drug reaction  Profound Dehydration  C. Diff Infection  Bowel Injury  Early Ulcer  Prolonged Ileus 3 (0.09%) 3 (0.09%) 3 (0.09%) 2 (0.07%) 2 (0.07%) 2 (0.07%) 2 (0.07%) 1 (0.04%) 1 (0.04%) 1 (0.04%) 1 (0.04%) 1 (0.04%) 1 (0.04%)
  • 19. LONG TERM COMPLICATIONS (15%)  Fifteen percent of patients had some form of complication.  Dyspepsia/Gastritis  Anemia  Ulcer  Diarrhea  Fainting  Malnutrition w Revision  Hypo/Hyper-vitaminosis  Kidney stones  Gallbladder (5.2%), (3.1%) (2.4%) (1.2%) (1.1%) (1.1%) (1.0%) (1.0%) (0.9%)
  • 20. LONG TERM COMPLICATIONS (15%)  Major Hair Loss (0.8%)  Persistent Dumping (0.7%)  Unmanageable Gas (0.6%)  Malnutrition w/o Revision (0.5%)  Hernia, Gout, Weight Regain (>20 lbs.), Severe Hypoglycemia (0.3%)  Severe Osteoporosis, Drug Withdrawal, Yeast infection, Lactose Intolerant, Low Estrogen, Bowel Obstruction (0.2%)  Constipation, Revision for Bile Reflux, Pain, Drug Allergy, Heavy Menstruation, Neuropathy, Hyper/Hypoglycemia, Allergic Reaction and Low Potassium (0.1%)
  • 21. BILE REFLUX  Bariatric Surgeons have raised concerns about Bile Reflux complications after Mini-Gastric Bypass  Recent studies have reported revisions to RNY for “bile reflux”  While Dyspepsia and Ulcers were common only 3 required revision for bile reflux  In this series symptoms of dyspepsia and marginal ulcers were treated successfully with Antacid (Prilosec, etc.) therapy
  • 22. CONCLUSIONS  Mini-Gastric Bypass  Short  Simple  Low Risk  Effective  Reversible and Revisable  Durable
  • 23. CONCLUSIONS  The present series reconfirms that the Mini-Gastric Bypass:  Short safe and effective weight loss therapy.  This study delineates the spectrum and frequency of complications after early and late after the MGB.
  • 24. CONCLUSIONS  The most frequent complications late after MGB are Dyspepsia/Gastritis, Iron Deficiency Anemia and Marginal Ulcer.  In most cases these complications responded to medical therapy.  This study shows the range of late complications following the MGB.
  • 25. FEARS ABOUT “BILE REFLUX”  Early days of gastric bypass loop placed adjacent to the esophagus led to …  “…bilious vomiting was particularly annoying and persistent in the first (loop) patients and resulted in a change of technique to the Roux-en- Y reconstruction”. (Griffen et al)  Others reported the need for RNY surgery for MGB associated “Bile Reflux” (Johnson et al)
  • 26. CONCLUSIONS: BILE REFLUX REDUX  The present series demonstrates that, while the symptoms of dyspepsia and ulcers were relatively common, they were routinely treated successfully with antacids medications (i.e. PPI etc.)  Surgery was necessary in only 3 patients for symptomatic “Bile Reflux” symptoms unresponsive to medical therapy
  • 27. GIL GERARD "BUCK ROGERS", TV STAR UNDERWENT MINI-GASTRIC BYPASS SURGERY. Gil Gil Gil Gerard Gerard Gerard “Buck In London Post Rogers” MGB (1979- 2005 2006 1981) 180 lbs. 340 lbs. 205 lbs. http://www.youtube.com/view_play_list?p=7BF29152EEF52939
  • 28. Steps in Performance of MGB Gil Gil Gil Gerard Gerard Gerard