BIOCHEM: List and briefly describe the six types of the 6 basic receptor types (own words not book words). Solution Internal receptors; theses are placed as intracellular or cytoplasmic receptors, situated in the cytoplasm of the cell and respond to hydrophobic ligand molecules which are able to travel across the plasma membrane. Cell-Surface Receptors: they are also known as transmembrane receptors, and actually are cell surface, membrane-anchored, or integral proteins that bind to external ligand molecules. Ion channel-linked receptors are such type whicb are able bind a ligand and open a channel through the membrane which allows specific ions to pass through. G-protein-linked receptors are those which are able to bind a ligand and activate a membrane protein called a G-protein which then interacts with either an ion channel or an enzyme in the membrane. Enzyme-linked receptors are those which are on cell-surface receptors with intracellular domains that are associated with an enzyme..