Adaferin (Adapalene Gel 0.1%) is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions.

1. Adaferin (Adapalene Gel)
© Clearsky Pharmacy
Adaferin (Adapalene Gel 0.1%) is a retinoid,
which is used for the topical treatment of acne
vulgaris in patients 12 years of age and older.

2. Adaferin Gel
© Clearsky Pharmacy
Adaferin Gel 0.1% is manufactured by
Galderma India Pvt. Ltd.
(Website: www.galderma.in)

3. Adapalene Gel – Brand Names
© Clearsky Pharmacy
Adapalene gel is available as
Differin, Adaferin, Adaclene, Aclene,
Acneril, Acniriv A, Adapen, Adaple
Gel, Adaret, Adiff, Adina and Aditop.

4. Active Ingredient
© Clearsky Pharmacy
The active ingredient contained in Adaferin
Gel is Adapalene. Each gram of Adaferin
0.1% Gel, contains 1 mg Adapalene in an off-
white aqueous gel.

5. Chemical Structure
© Clearsky Pharmacy
The structure of Adapalene is given below:

6. Uses of Adaferin Gel
© Clearsky Pharmacy
Adaferin (Generic Adapalene Gel
0.1%) is a third-generation topical
retinoid primarily used in the
treatment of mild-moderate acne,
and is also used off-label to treat
keratosis pilaris as well as other
skin conditions. Adaferin is used
on the face, chest or back for acne,
where the skin has lots of
blackheads, spots and pimples.

7. Storage Instructions
© Clearsky Pharmacy
Adaferin (Generic Adapalene 0.1% Gel)
has to be stored at controlled room
temperature i.e. from 20°C to 25°C (68°F
to 77°F).
Keep this as well as all other medicines
away from children and pets.

8. Dosage
© Clearsky Pharmacy
➢ Apply a thin film of Adaferin Gel 0.1% to the
entire face and any other affected areas of the
skin once daily in the evening, after washing
gently with a non-medicated soap. Avoid
application to the areas of skin around eyes,
lips, and mucous membranes.
The dosage of Adaferin Gel (Adapalene 0.1%
Gel ) is given below:

9. Warnings
© Clearsky Pharmacy
Do not use Adaferin gel on areas where you have
cuts or scrapes or if you have a skin condition called
eczema.
Avoid contact with the eyes, mouth or nostrils, and
avoid other very sensitive areas of the body. In case
accidental contact does occur, immediately wash
with warm water.
Avoid exposure to strong sunlight and artificial UV
light.
In case you experience sensitivity or irritation when
using this medicine, stop using it and tell your
doctor.
You may be asked to use the gel less often, or to
stop using it for a short time.

10. Adaferin Gel 0.1%
© Clearsky Pharmacy
Contraindications
Adaferin gel is contraindicated in patients with a
hypersensitivity to Adapalene or any other
component of this medication.

11. Adaferin Gel Side Effects
© Clearsky Pharmacy
➢Dry skin of mild to moderate
severity was the most frequently
reported Adaferin side effect with an
incidence rate of 1% or more. The
other treatment related side effects
were Erythema, scaling, dryness,
burning/stinging.

12. Adaferin Gel Overdose
© Clearsky Pharmacy
Adaferin (Adapalene gel) is intended for
cutaneous use only.
If the medicine is applied excessively, no
more rapid or better results will be obtained
and marked redness, peeling, or discomfort
may occur.

13. Adapalene During Pregnancy
© Clearsky Pharmacy
Adaferin (Adapalene gel) has been
classified by the US FDA as
Pregnancy Category C.
There are no adequate and well-
controlled studies in pregnant women.
Adapalene should be used during
pregnancy only if the potential benefit
justifies the potential risk to the fetus.

14. Adaferin (Adapalene Gel 0.1%)
For more details on
Adaferin Gel click here
© Clearsky Pharmacy
Adaferin (Adapalene Gel 0.1%) by
Galderma India Pvt. Ltd.