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BY: AYODEJI ADEYEMI

PRESENTATION
ON THE
STOMACH
WHAT IS STOMACH

The stomach
is a muscular
J-shape organ
of the
digestive tract.

It secretes
hormone
called gastrin
into the blood.

It temporarily
store and
mixes food

It secretes
gastric juice
into the lumen
DESCRIPTION
The stomach is
located in the upper
left quadrant of the
abdomen, just
beneath the
diaphragm.

It is positioned
between the
esophagus and the
small intestine.

There is a sphincter
between the esophagus
and the stomach, which
allow food to pass into
the stomach and
prevent chyme from
flowing backwards into
the esophagus
STOMACH IS DIVIDED INTO THREE PORTIONS

Fundus- upper
portion near
esophagus

Antrumbottom
portion
where pyloric
located

The body- the
middle
section
The wall of the stomach
is made up of four layers

The
mucous

The mucous and submucous layers
are made up of ridges called rugae.
Within the ridges are gastric glands
made up of;

Mucous cells

The
submucous
The
muscular

Parietal cells

Chief cells

And G-cells

The
peritoneal

Each of these cells secretes a chemical
that aids the process of digestion.
SECRECTION IN THE STOMACH

EXOCRINE

Exocrine glands are located in the fundus and
body of the stomach. The chief cells in these
exocrine glands secrete pepsinogen, the
inactive precursor of pepsin. also contain
parietal cells. These parietal cells secrete
hydrochloric acid(HCl), which makes the
stomach strongly acidic, with a pH of about 2
or 3. This is an optimal pH for the action of
pepsin

ENDOCRINE

The G-cells are the
only endocrine cells
located in the stomach
and are located
mainly in the antrum
of the stomach where
there are few acid
producing cells.

Gastrin acts on the
parietal cells,
stimulating them to
release hydrocloric
acid

G-cells release the
hormone gastrin into
the bloodstream.
Muscular Activity

The stomach must undergo
muscular contractions in order to
mix food and gastric juices
together. These waves of
involuntary muscular contractions
are called peristalsis. When food
is present, peristaltic contractions
pass through the stomach muscles
about two or three times every
minute and continue at a constant
rhythm.

Pressure will begin to develop in
the lower part of the stomach.
When there is sufficient pressure,
a small amount of the stomach's
contents moves through the
pyloric sphincter and into the
duodenum (the first section of the
small intestine). It takes about
two to six hours for the entire
contents of the stomach to empty,
depending on the composition of
the person's diet.

Low-fat meals leave the stomach
more quickly than high-fat meals.
Psychological states also affect the
rate of stomach emptying;
depression and fear may cause the
stomach to empty slowly, while
anger and aggression may cause
the stomach to empty quickly.

After the chyme has entered the
duodenum and the pyloric
sphincter has closed, some of the
food returns to the stomach
through retropulsion.
Retropulsion is a process in which
the stomach contents are squirted
back into the stomach at a rate of
about three times per minute.
Retropulsion mixes the food with
gastric juices and breaks larger
clumps of food into smaller
pieces.
Role In Human Health
ο‚— The stomach prepares food for digestion in the small

intestine. If the stomach is not functioning properly,
there are many problems that can arise with regard
to digestion. Further, the contents of the stomach are
so acidic and caustic to other organs of the body that
they can cause problems if they leak out of the
stomach, as may happen with perforating ulcers of
the duodenum or penetrating wounds of the
abdomen.
COMMON HEALTH PROBLEM

Gastritis

Gastroenteritis

Peptic ulcer disease

Gastroesophageal
reflux

Gastritis : It is an
inflammation of the
gastric mucosal layer
caused by a range of
factors, including
bacterial infections,
medications
(particularly NSAIDs),
acute stress, and spicy
foods or alcohol.

Gastroenteritis is
another common
disorder of the digestive
tract, characterized by
inflammation of the
stomach and the
intestines. is caused by
specific bacteria
(Staphylococcus aureus,
Escherichia coli, etc.),
amoebae or other
parasites. The
symptoms include
diarrhea, nausea,
vomiting, and
abdominal cramping.

Peptic ulcers can occur
in the stomach,
although they are more
likely to develop in the
small intestine. Small
lesions develop in the
mucosal membrane,
causing bleeding. Other
symptoms include
heartburn and
indigestion.

Gastroesophageal reflux
is caused by a
malfunctioning
sphincter between the
esophagus and the
stomach, resulting in a
release of chyme back
into the esophagus.
CONCLUSION
ο‚— The stomach is a muscular organ of the digestive

tract. It is located between the esophagus and the
small intestine. The stomach is hollow and sacshaped. It is involved in the second phase of
digestion, following mastication (chewing).The
stomach produces protease enzymes and
hydrochloric acid which kills bacteria and gives the
right pH for the protease enzyme to work.
THANK YOU!
I HOPE YOU ENJOY
THE PRESENTATION

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Stomach help

  • 2. WHAT IS STOMACH The stomach is a muscular J-shape organ of the digestive tract. It secretes hormone called gastrin into the blood. It temporarily store and mixes food It secretes gastric juice into the lumen
  • 3. DESCRIPTION The stomach is located in the upper left quadrant of the abdomen, just beneath the diaphragm. It is positioned between the esophagus and the small intestine. There is a sphincter between the esophagus and the stomach, which allow food to pass into the stomach and prevent chyme from flowing backwards into the esophagus
  • 4. STOMACH IS DIVIDED INTO THREE PORTIONS Fundus- upper portion near esophagus Antrumbottom portion where pyloric located The body- the middle section
  • 5. The wall of the stomach is made up of four layers The mucous The mucous and submucous layers are made up of ridges called rugae. Within the ridges are gastric glands made up of; Mucous cells The submucous The muscular Parietal cells Chief cells And G-cells The peritoneal Each of these cells secretes a chemical that aids the process of digestion.
  • 6. SECRECTION IN THE STOMACH EXOCRINE Exocrine glands are located in the fundus and body of the stomach. The chief cells in these exocrine glands secrete pepsinogen, the inactive precursor of pepsin. also contain parietal cells. These parietal cells secrete hydrochloric acid(HCl), which makes the stomach strongly acidic, with a pH of about 2 or 3. This is an optimal pH for the action of pepsin ENDOCRINE The G-cells are the only endocrine cells located in the stomach and are located mainly in the antrum of the stomach where there are few acid producing cells. Gastrin acts on the parietal cells, stimulating them to release hydrocloric acid G-cells release the hormone gastrin into the bloodstream.
  • 7. Muscular Activity The stomach must undergo muscular contractions in order to mix food and gastric juices together. These waves of involuntary muscular contractions are called peristalsis. When food is present, peristaltic contractions pass through the stomach muscles about two or three times every minute and continue at a constant rhythm. Pressure will begin to develop in the lower part of the stomach. When there is sufficient pressure, a small amount of the stomach's contents moves through the pyloric sphincter and into the duodenum (the first section of the small intestine). It takes about two to six hours for the entire contents of the stomach to empty, depending on the composition of the person's diet. Low-fat meals leave the stomach more quickly than high-fat meals. Psychological states also affect the rate of stomach emptying; depression and fear may cause the stomach to empty slowly, while anger and aggression may cause the stomach to empty quickly. After the chyme has entered the duodenum and the pyloric sphincter has closed, some of the food returns to the stomach through retropulsion. Retropulsion is a process in which the stomach contents are squirted back into the stomach at a rate of about three times per minute. Retropulsion mixes the food with gastric juices and breaks larger clumps of food into smaller pieces.
  • 8. Role In Human Health ο‚— The stomach prepares food for digestion in the small intestine. If the stomach is not functioning properly, there are many problems that can arise with regard to digestion. Further, the contents of the stomach are so acidic and caustic to other organs of the body that they can cause problems if they leak out of the stomach, as may happen with perforating ulcers of the duodenum or penetrating wounds of the abdomen.
  • 9. COMMON HEALTH PROBLEM Gastritis Gastroenteritis Peptic ulcer disease Gastroesophageal reflux Gastritis : It is an inflammation of the gastric mucosal layer caused by a range of factors, including bacterial infections, medications (particularly NSAIDs), acute stress, and spicy foods or alcohol. Gastroenteritis is another common disorder of the digestive tract, characterized by inflammation of the stomach and the intestines. is caused by specific bacteria (Staphylococcus aureus, Escherichia coli, etc.), amoebae or other parasites. The symptoms include diarrhea, nausea, vomiting, and abdominal cramping. Peptic ulcers can occur in the stomach, although they are more likely to develop in the small intestine. Small lesions develop in the mucosal membrane, causing bleeding. Other symptoms include heartburn and indigestion. Gastroesophageal reflux is caused by a malfunctioning sphincter between the esophagus and the stomach, resulting in a release of chyme back into the esophagus.
  • 10. CONCLUSION ο‚— The stomach is a muscular organ of the digestive tract. It is located between the esophagus and the small intestine. The stomach is hollow and sacshaped. It is involved in the second phase of digestion, following mastication (chewing).The stomach produces protease enzymes and hydrochloric acid which kills bacteria and gives the right pH for the protease enzyme to work.
  • 11. THANK YOU! I HOPE YOU ENJOY THE PRESENTATION