2. MAMMOGRAPHY - INDICATIONS
Screening of asymptomatic women.
Screening of high risk women.
Follow up of patients after mastectomy of same and opposite breast / same breast with implant
Investigations of benign breast diseases with eczematous skin,nipple discharge , skin thickening .
Investigation of a breast lump.
Investigation of occult primary with secondaries .
Male breast evaluation .
3. TYPE OF MAMMOGRAPHIC EXAMINATION
Diagnostic mammography
Is performed on patients with symptoms or elevated risk factors.
Two or three views of each breast may be required.
Screening mammography
Is performed on asymptomatic women with the use of a two view protocol,
usually medial lateral oblique and cranio caudal , to detect on unsuspected cancer
4. MAMMOGRAPHY - BASICS
Uses low-energy x-rays (40kVp) for dectecting breast pathologies.
Higher kV - Poor Contrast
Lower kV - Good Contrast
Tissues within breast have very small difference in attenuation property - Lacks contrast
<40kVp - Good photoelectric effect - brings out contrast between the tissues within the breasts.
Better contrast
Better detailing of structures
5. INSTRUMENTATIONS
HIGH FREQUENCY X-RAY GENERATOR
X-RAYTUBE
ANODE
CATHODE
BEAM PORT
K-EDGE FILTERS
COMPRESSION PADDLE
SPOT COMPRESSION
PARALLEL LINEAR GRID
IMAGE RECEPTOR
AEC (AUTOMATIC EXPOSURE CONTROL)
6. X-RAY TUBE
Rotating Anode type
- Glass or Metal ceramic
Advantage
-Decreases off focus radiation
-IncreasesTube lighting
Cathode - Dual focalspots
0.3mm (Imaging)
0.1 mm (Magnification)
( Focal spot - Penumbra - Resolution)
Helps identifiying microcalcification
7. ANODE (TARGET)
Usually-Tungsten (xray /Floro/ CT/ cathlab)
MOLYBDENUM -17.5 & 19.6 keV
RHODIUM -20.2 & 22.7 keV
CHARACTERISTIC RADIATION
Characteristic x-ray Characteristic x-rays are produced after ionization of a k- shell electron.When an outer-shell
electron fills the vacancy in the k shell, an x-ray is emitted.
In mammography,17.5- 19.5kev characteristic x-ray is produced with Mo and 23kev is produced with Rh
8.
9. ANODE ANGLE = 16° to 0 to -9°
EFFECTIVE ANODE ANGLE
- Angle of anode relative to the horizontal tube mount
XRAYTUBE TILT
-To reduce unwanted radiation
- focus only to the breast area
10. SOURCETO IMAGE DISTANCE (SID)
- lesser than usual Radiography -60/65 cm (Chest = 18)
- short SID
- Heel Effect utilized
At Cathode → chestwall – Thicker tissues
SIDE
At Anode → Nipple region – LessThickness
SIDE
Non-uniformity of X-ray Intensity
Along the cathode side - More Intensity
Along the Anode side - Less Intensity
11. PARTS OF MAMMOGRAPHY EQUIPMENT
Beam port - 1 mm Beryllium
Since metal/ Glass is used in XRAYTUBE
metal will absorb the low energy photons from xray tube
K-edge filters - Cuts unwanted Low energy photons (RADIATION)
/ High energy photons (SCATTER – Reduces contrast)
(0.03mm Mo / 0.025mm Rh)
12. PARTS OF MAMMOGRAPHY EQUIPMENT
To decrease Breast thickness, spreads out the tissue
- Spreads out superimposed anatomy.
Scatter Radiation - contrast
Radiation dose to the breast tissue
Geometric Blurring (closer to image receptor )
Decreases the kinetic blur .
Makes breast thickness uniform in film density.
Differentiates the easily compressible cysts and fibro-
glandular tissue from the more rigid carcinomas
Separates the super imposed breast lesions .
Compression paddle
13. PARTS OF MAMMOGRAPHY EQUIPMENT
GRIDS
Stationary grids or grids placed in between the screen and the film are no longer used as the thin grid lines
compromised on the quality of the image .
Covered tiny details such as microcalcifications
Hence oscillating grids are used o Grid ratio of 4 :1 or 5 : 1
The grid lines are eliminated by the motion of the grid .
Grids improve the image quality and cause a significant reduction
14. PARTS OF MAMMOGRAPHY EQUIPMENT
Spot.compression - for imaging particular region
Parallel Linear grid - (4:1 to 5:1) low grade ratio grids used
to increase the Contrast
Image Receptor
Screen film
CR Cassette
Flat panel detector - (Digital Mammography)
AEC -Automatic Exposure Control
KeV selected → MAS automatically chosen.
15. FLAT PANEL DETECTORS - INDIRECT
Indirect Amorphous silicon technology
Xray scintillator (Gradoliniun Sulphate / Csl)
Produces light flashes when Xray beam falls over it.
Silicon Photodiode array (Photo detector)
Made of Amorphous silicon
Converts light photons from the scintillator into electrical signal
TFT-electronic switch
- Reads electrical signal
- Gives positional information
-This data is sent to AEC (Analogue to Digital Converter)
AEC
Converts it into digital signal and are finally sent to Computer for processing
Disadvantage - LIGHT SCATTER
Scattering of light within the phosphors leading to unsharpness
16. FLAT PANEL DETECTORS - DIRECT
Crystals of amorphous selenium
directly converts Xrays into electrical signal that is stored in a capacitor (ready to be read)
17. MAGNIFICATION TECHNIQUE
To increase the visibility of finer details like microcalcification
Increase O ID - object to Image Distance
Breast is kept over a raised platform
No need for grid as there is presence of air gap
18. SCREEN FILM MAMMOGRAPHY
Old method
The image is created directly on a film-Non modifiable
Less sensitive for women with dense breasts
Screen film cassette used
Single emulsion film
Single screen
Terbium activated Gadolinium oxysulphide
Screen emits green light
Film will be sensitive to greenlight (ORTHOCHROMATIC FILM)
19. COMPUTER RADIOGRAPHY (CR) MAMMOGRAPHY
A/K/A Filmless radiography
Electronic radiography
Digital storage phosphor imaging
Xray images are acquired in digital format
Photostimulable phosphor plates used
Imaging plate has high sensitivity to xrays
COMPONENTS
storage phosphor cassette
Storage phosphor reader
Bar code scanner
Workstation
Photostimuliable Phosphor (PSP) Cassette
PSP Receptor materials
. BaFBr : Eu2+
. BaF (Br1): Eu 2+
.Ba SrFBr:Eu 2+
20. DIGITAL MAMMOGRAPHY
Also called full-field digital mammography (FFDM)
-in which the x-ray film is replaced by electronics that convert x-rays into mammographic pictures of the breast.
Display Monitor - HIGH RESOLUTION (5 MP)
Direct Digital Mammography
- Flat panel detector with amorphous selenium array
Indirect Digital Mammography
-Flat panel scintillator with amorphous silicon diode array
21. DIGITAL MAMMOGRAPHY
ADVANTAGE
Better contrast,more details.Better delineation of parenchyma & subcutaneous tissue
Better noise level reduction
Tolerance to over/under exposure (Avoids Repetition?
Post-processing techniques for better diagnosis
Radiation dose is decreased- Mean glandular dose in mammography
Screen Film (2-3m bGy)
Digital (20-30% reduction)
Image can be seen quickly and stored digitally(less storage space )
22. LIMITATIONS OF 2D MAMMOGRAPHY
20% of cancers will be missed
10% recalled for additional workup
75-80% of biopsies result in benign lesions
sensitivity decreases with increased breast density
2D mammograms,take images only from the front and side, this may create images with
overlapping breast tissue
23. ADVANCES IN DIGITAL MAMMOGRAPHY
Computer -Aided Diagnosis
- uses software to detect area of clinical significance and highlight them for better output image
Digital BreastTomosynthesis (DBT)
XrayTube rotates /moves in a 50-55° arc around the breast,
capturing several (11-25) low dose projections of the breast at different angles.
Then reconstructed to 3D Projection images (1 mm slices)
3D MAMMOGRAPHY
24. DIGITAL BREAST TOMOSYNTHESIS - DBT (3D MAMMOGRAPHY )
Disadvantages of DBT
• Twice the radiation compared to 2D mammo
• More storage requirements
• Takes longer time to read
• Cannot be read on demand
Advantages of DBT
• Increased cancer detection rate
• Lesions are better defined
• Precise location of lesions
• Less false positive recalls
3D MAMMOGRAPHY
26. HOW MAMMOGRAM IS PERFORMED ?
CRANIO CAUDAL (CCVIEW)
demonstrate maximum tissue on both medial and lateral
aspects of the breast with the retromammaryspace and some
pectoral muscle
The following points were analyzed on CC view:
nipple should be in profile
nipple should point straight and should not be pointing lateral
or medial
PND (pectoral nipple distance) must be within 1 cm of the
same measurement of the MLO view.
27. HOW MAMMOGRAM IS PERFORMED ?
MEDIOLATERAL OBLIQUE(MLOVIEW)
demonstrate axilla,axillary tail,and inframammary
fold with all the breast tissue
The following points were analyzed on MLO view:
Breast should be pulled out with nipple in profile
The pectoralis muscle margin should be well visualized
The lower edge of pectoralis muscle should be at the level
of pectoralis–nipple line (PNL) or below
PND must be within 1 cm of the same measurement of
the MLO view.
When MLO image of both breasts are viewed as mirror
images,pectoralis muscle should meet in the midline and
form a “V”.
28. OTHER VIEWS
Latero-medial (LO) - from the outside towards the center
Medio-lateral (ML) - from the center towards the outside
Spot compression - compression on only a small area,to get more detail
Cleavage view - both breast compressed,to see tissue near the center of
the chest
Magnification -to see borders of structures and calcifications
29.
30. REPORTING A MAMMOGRAM
Breast Imaging Reporting and Data System (BI-RADS)
RISKASSESSMENT AND QUALITYASSURANCETOOL developed byAmerican college of radiology (ACR)
that provides a widely accepted lexicon and reporting schema for imaging of the breast.
All mammographic, ultrasound and breast MRI findings and reports should closely adhere to the BI-RADS lexicon
and assessment categories.