In this interview, Dr. Peter Margolis, M.D., Ph.D. talks about his work in collaborative medicine as Co-Director of the The Center for Health Care Quality at Cincinnati Children's Hospital Medical Center. He shares an overview of his work in the last twenty years to improve quality systems health care delivery for children. Dr. Margolis discusses his view of health care systems, and the value strengthening social network practice, mapping, and analysis bring to improving innovative practices and knowledge sharing. His research discovers the value of networks, collaboration, communication and community to advance medical innovation and health care service amongst large networks of health care center staff, patients, and their families. By understanding systems and building network infrastructure, health care services will have the capacity to serve every individual as well as sustain knowledge systems to advance both the science and tacit knowledge of practitioners and their patients.