What are the respiratory and fermentation pathways in Chlamydia pneumoniae? Solution Chlamydophila pneumoniae is, an obligate intracellular bacterium which infects humans and is one of the major cause of pneumonia. It is gram negative bacterium. As it is an obligate parasite it is difficult to distinguish between the host and parasite metabolism. There are major differences in the metabolic pathways in various developmental stages. C. pneumoniae requires oxygen to survive, but requires environments with lower levels of oxygen than present in the atmosphere These bacteria shows metabolism of glucose-6-phosphate to pyruvate via glycolysis, which allows them to generate ATP via substrate-level phosphorylation by the enzymes phosphoglycerate kinase and pyruvate kinase. The TCA cycle is complete in all Chlamydiae thus able to oxidize acetyl-CoA, accompanied by regeneration of the energy-rich molecules NADH, FADH2 and GTP. The electron transport chain of environmental chlamydiae is branched. H+ translocating NADH dehydrogenase, additional terminal oxidases, and cytochrome c oxidases, altogether were suggested to enable these bacteria to build up a proton gradient more efficiently and potentially allow them to respond to changing conditions such as fluctuating oxygen tensions. They also have increased capacities for host-independent production of ATP via oxidative phosphorylation..

1. What are the respiratory and fermentation pathways in Chlamydia pneumoniae?
Solution
Chlamydophila pneumoniae is, an obligate intracellular bacterium which infects humans and is
one of the major cause of pneumonia. It is gram negative bacterium. As it is an obligate parasite
it is difficult to distinguish between the host and parasite metabolism. There are major
differences in the metabolic pathways in various developmental stages.
C. pneumoniae requires oxygen to survive, but requires environments with lower levels of
oxygen than present in the atmosphere
These bacteria shows metabolism of glucose-6-phosphate to pyruvate via glycolysis, which
allows them to generate ATP via substrate-level phosphorylation by the enzymes
phosphoglycerate kinase and pyruvate kinase.
The TCA cycle is complete in all Chlamydiae thus able to oxidize acetyl-CoA, accompanied by
regeneration of the energy-rich molecules NADH, FADH2 and GTP.
The electron transport chain of environmental chlamydiae is branched. H+ translocating NADH
dehydrogenase, additional terminal oxidases, and cytochrome c oxidases, altogether were
suggested to enable these bacteria to build up a proton gradient more efficiently and potentially
allow them to respond to changing conditions such as fluctuating oxygen tensions.
They also have increased capacities for host-independent production of ATP via oxidative
phosphorylation.