What\'s the relationship between DNA and RNA? What\'s the relationship between DNA and RNA? Solution Both of them nucleic acids.apart from that there is a connection between these two in expressing a gene.as we know that in central dogma of molecular biology both DNA and RNA are related very closely.in the first step of expression information present in the complementary strand of DNA has to be copied into m-RNA. It further translates the information to protein sequence with the help of r- RNA, t-RNA and ribosome..