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A common symptom of pharyngitis is swelling of the. interior cervical lymph nodes. Why might
lymph nodes swell in the presence of an infection? What else may cause swollen lymph nodes?
(What part of the immune response causes swelling?) Explain why conditions that cause
destruction of B lymphocytes and/or T lymphocytes cause malfunctioning of both the specific
and nonspecific immune responses. You are running an ELISA on a sample to test for the
presence of antigens from the influenza A virus. When it comes time to add the antibody, you
realize that you only have antibodies for the influenza B virus. Would these antibodies give you
accurate results? Why or why not?
Solution
4. lymph nodes contain clusters of immune cells.Lymph nodes act as filters ,removing infectious
germs or foreign cells bought to them via the lymphatic vessels. Swelling occurs in lymph nodes
when the number of white blood cells increase due to an infection. The number of immune cells
increases rapidly which causes pressure and swelling inside the lymph nodes.In case of
pharyngitis,there is inflammation of the pharynx which is in the back of the throat therefore it
cause inflammation of the anterior cervical lymph nodes which are present in the neck. The
causative agent of pharngitits is mostly group A streptococcus,so it is filtered in the anterior
cervical lymph nodes.
Lymph node sweliing also takes place in a case of cancer. For example in case lymphoma which
is cancer of the lymph node,leukaemia,melanoma.Lmph node swelling also occurs in
autoimmune disorders such as rheumatoid arthritis,systemic lupus erytematosus(SLE).
5. The T and B lymphocytes are involved in the recognition of specific antigens. Once the
antigen is recognized ,The function of B cells is to produce antibodies which help in the
neutralization of pathogens.On the other hand T cells are involved in production of
cytokines,which functions by activating the immune cells.B and T lymphocytes are also involved
in many inflammatory responses which come under non specific defenses. Therefore destruction
of B and T lymphocytes will cause malfunctioning of both specific and nonspecific immnune
responses.
6. While perfoming ELISA antibodies from influenza b virus cannot be used fo detection of
antigens of inflenza a virus.Antibody specific to antigens of infuenza A virus will only give
positive results for ELISA .ELISA test is based on specif antigen antibody interaction therefore
inorder to detect antigen of Infuenza A antibody specific for inflenza a virus will be needed.

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A common symptom of pharyngitis is swelling of the. interior cervical.pdf

  • 1. A common symptom of pharyngitis is swelling of the. interior cervical lymph nodes. Why might lymph nodes swell in the presence of an infection? What else may cause swollen lymph nodes? (What part of the immune response causes swelling?) Explain why conditions that cause destruction of B lymphocytes and/or T lymphocytes cause malfunctioning of both the specific and nonspecific immune responses. You are running an ELISA on a sample to test for the presence of antigens from the influenza A virus. When it comes time to add the antibody, you realize that you only have antibodies for the influenza B virus. Would these antibodies give you accurate results? Why or why not? Solution 4. lymph nodes contain clusters of immune cells.Lymph nodes act as filters ,removing infectious germs or foreign cells bought to them via the lymphatic vessels. Swelling occurs in lymph nodes when the number of white blood cells increase due to an infection. The number of immune cells increases rapidly which causes pressure and swelling inside the lymph nodes.In case of pharyngitis,there is inflammation of the pharynx which is in the back of the throat therefore it cause inflammation of the anterior cervical lymph nodes which are present in the neck. The causative agent of pharngitits is mostly group A streptococcus,so it is filtered in the anterior cervical lymph nodes. Lymph node sweliing also takes place in a case of cancer. For example in case lymphoma which is cancer of the lymph node,leukaemia,melanoma.Lmph node swelling also occurs in autoimmune disorders such as rheumatoid arthritis,systemic lupus erytematosus(SLE). 5. The T and B lymphocytes are involved in the recognition of specific antigens. Once the antigen is recognized ,The function of B cells is to produce antibodies which help in the neutralization of pathogens.On the other hand T cells are involved in production of cytokines,which functions by activating the immune cells.B and T lymphocytes are also involved in many inflammatory responses which come under non specific defenses. Therefore destruction of B and T lymphocytes will cause malfunctioning of both specific and nonspecific immnune responses. 6. While perfoming ELISA antibodies from influenza b virus cannot be used fo detection of antigens of inflenza a virus.Antibody specific to antigens of infuenza A virus will only give positive results for ELISA .ELISA test is based on specif antigen antibody interaction therefore inorder to detect antigen of Infuenza A antibody specific for inflenza a virus will be needed.