List three ways the epinephrine signaling pathway, phosphoinositide pathway, insulin signaling pathway, and EGF signaling pathway are SIMILIAR NO ESSAY JUST THE EXAMPLES Solution 1.They share many downstream components. For example, EGF can evoke metabolic responses, e.g., GLUT4 translocation whereas insulin can be mitogenic, especially in cancer cells. EGFR and IR activate same key signal transducers, although either receptor can stimulate both the Ras/ERK and PI3K/AKT pathways, the major routes of activation are different. 2. Receptors are membrane bound in all these signalling pathways. 3.They have a ligand-binding site on the cytosolic side of the membrane..

1. List three ways the epinephrine signaling pathway, phosphoinositide pathway, insulin signaling
pathway, and EGF signaling pathway are SIMILIAR
NO ESSAY JUST THE EXAMPLES
Solution
1.They share many downstream components.
For example, EGF can evoke metabolic responses, e.g., GLUT4 translocation whereas insulin
can be mitogenic, especially in cancer cells.
EGFR and IR activate same key signal transducers, although either receptor can stimulate both
the Ras/ERK and PI3K/AKT pathways, the major routes of activation are different.
2. Receptors are membrane bound in all these signalling pathways.
3.They have a ligand-binding site on the cytosolic side of the membrane.