What in this picture would allow me to visualize the G-protein coupl.pdf

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What in this picture would allow me to visualize the G-protein coupled receptor? BIO 331 Extra credit - 10 POINTS!! - Using your clay, model a Gprotein coupled receptor. Use different colors to identify the hydrophobic start/stop portions of the protein and another color to identify +ve charged residues. - Use your model to determine the final structure of the protein within the membrane if a mutation occurred at the 4th a mutation occurred at the 4th hydrophobic (start) sequence, 0 Schematic drawing of structure rendering it non-functional. Draw your final structure and submit for 5 extra credit points. - Due end of day SATURDAY.

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What are the most important issues that an HR team needs to consider when deciding to use an employee survey or some other method? Gather any kind of feedback, whether through a survey or other method, creates an expectation for employees that change will happen in line with their response/information. What are does things HR professionals need to keep in mind when managing expectations about change flowing from employee feedback?.

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What does compile-time type checking do? [6 marks] a. Allow a single type for each expression b. Check for type consistency of each operator at compile time c. Report where in source code the error is found d. Catch all errors before runtime Which of the following type errors can be caught at compile time? [6 marks] a. adding an integer with a string b. An array being accessed out-of-bound c. Null pointer dereference d. A value being casted to an unrelated type e. Dividing a value by zero.

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What does HSAM stand for? What is the range of memory accuracy for HSAMs? Based on the brain scans of 12 HSAMs, which part of the brain appears to more active when they recall memories? What type of research is being conducted when a scientist takes functional brain scans while a participate in rememberingdescriptive, predictive or experimental? What research methods are scientists using when they study the memory of 11-year old HSAM, Jake Hassler, as he developscase study, self-report, observation, correlational study, experiment? What two questions are researches trying to answer by studying HSAMs? WHAT IS MEMORY? (9:46) What structure in the brain did researchers discover is important for forming and maintaining new long-term memories from the case of HM (Henry Molaison)? According to your textbook CH 07 Memory, what type of memories are formed by this structure? Why did surgeons remove this structure from HMs brain? Did the surgery cure his disorder? What was a major unintended side effect of this surgery? Despite not having this structure in his brain, what types of memories could HM still develop? What task did scientist Brenda Milner use to demonstrate that HM could still form some types of long-term memories? How do we know that HM did not form an episodic memory of the task? How do we know that HM formed procedural memories of the task? According to your textbook CH 7 Memory, where are implicit memories formed in the brain? Describe the two studies conducted by researcher of Nobel Prize winner Eric Kandel by answering the questions that follow: For the first study, what was the question guiding the research? What was the subject for this study? Why did he choose this animal for his research? What type of research methods were used? What did he do? (method or procedure) What data did he collect? What did he find? (the results) How did he interpret the findings? (the conclusion) For Kandels second study, what was the question guiding the research? What was the subject for the study? Why did they choose this subject for their study? What type of research methods did Kandel use? What did he do? (the method/procedure) What data did he collect? What did he find? How did Kandel interpret the results? WHERE DOES MEMORY LIVE? (9:38) Where are memories stored in the brain? What is the role of the hippocampus in remembering? What happens to the integrity of a memory when you recall it? What is memory consolidation? Describe the study conducted by Karim Nadir by answering the questions below: What question were guiding his research? Who were his subjects? What did he do? (Method/procedure) What does the drug Azinomycin do? What data did Nadir collect? What did he find? (results) How did he interpret the findings? (Conclusion) On the whole, are memories reliable? Based on the research of Nadir, which is a better metaphor for memory storage? a letter in an envelope a book on a shelf in a library a file in a computer that you can open, edit and sav.

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Web Server Python Assignment You will develop a web server that handles one HTTP request at a time. Your web server should accept and parse the HTTP request, get the requested file from the servers file system, create an HTTP response message consisting of the requested file, and then send the response directly to the client. If the requested file is not present in the server, the server should send an HTTP 404 Not Found message back to the client. HTML File Create an HTML file and store this in the same directory as your server program. You can create any HTML file you would like for this assignment, but it should at a minimum contain a body of text. Server code Create the server socket (using TCP) and bind it to the IP address of the server and port number. Establish a listening socket to listen for incoming connections from a client. Establish a separate connection socket for the client-server. The server should then receive a request from the client. This message is the file name of the HTML file that the client is requesting. The HTML file needs to be stored in the same directory as the server script. The server will need to extract the requested object from the message and open the file to then read the contents of the requested file. The server then sends an HTTP response (the status code) if the file is found and then returns the contents of the file to the client. The connection socket is then closed since we are only servicing one request per connection. The server should send the appropriate status code to the client if the file is not found and close the connection socket. * There is nothing in the code shutting down the server program if the connection is successful, so make sure to kill the process manually when not working on the program. * Client Code Write your own HTTP client to test your server. Your client will connect to the server using a TCP connection. You will need to accept the IP address of the server and port number as input from the user. Send a request to the server. This is a message containing the file path of the file the client wants to retrieve. The file path is obtained as input from the user. Display the server response and contents of the file as output. The client should be able to receive all the bytes of data sent from the server regardless of the number of bytes of your specific HTML file. Close the connection.

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What could be the reason for a very faint colorimetric result in two of the samples compared to the positive control, and a possible negative result for the third sample? Post-Lab Assessment Ruffed lemurs found in the eastern rainforests of Madagascar typically live arboreally, in the crowns of large trees, with most of their time spent 15 to 25 meters (50-80 feet) above the forest floor. Their diet comprises mainly of fruit, flowers, and young leaves accessible year round. Prized for their meat and fur, ruffed lemurs have been hunted nearly to extinction. Many residents of Madagascar find a large portion of the protein in their diet from animals hunted in the rainforest. Called bushmeat, this form of protein can be a valuable dietary resource to people without access to other food. However, many wild animals carry diseases that can be transmitted through their blood to humans who are processing the meat for consumption. For example, the Ebola epidemic of 2014 likely began with the transmission of the virus from a fruit bat to humans in Guinea. In addition to hunting, ruffed lemurs also suffer from habitat loss due to deforestation, climate changes, and urban development. Because of these threats, the ruffed lemur became critically endangered in 2008 meaning the species faces a very high risk of extinction. Fortunately ruffed lemurs reproduce easily in captivity so they make an excellent species for reintroduction into the wild. Recently conservation biologists noticed that a conspiracy, or group, of lemurs in a Madagascar wildlife preserve were behaving oddly. Several lemurs were seen on the ground acting lethargic. The biologists sedated three lemurs to run some tests and see if they could understand this strange new behavior. All three of the lemurs had elevated body temperatures and appeared to be dehydrated and underweight as if they had not been eating regularly despite the availability of food in the tree tops of the preserve..

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What are the implications of the authors findings? How can this information be applied in the future? Comparative analyses of sequenced genomes have provided important insight into the HGT processes3,4 occurring in different complex environments3,4. Our CRISPR-based recording system adds more detailed insights into the dynamics of HGT in complex environments by detecting DNA transfer events as they occur, enabling detection of transient transfer events. The recording system captures spacers from HGT events stably into genomic arrays that can be used to identify mobile elements beyond current methodologies. The ability to detect, in real- time, transient transfer events and those occurring at low frequencies enables an in-depth characterization of mobile DNA in complex microbiomes. As DNA transfer is confined by recipient range we are only capable of recording DNA that can enter the E. coli BL21 recording strain. When using other E. coli strains as donor we showed that transfers can be resolved down to the individual plasmids from donors that can carry up to 6 putatively mobile plasmids. We find that the different plasmids varied in transfer efficiencies likely reflecting differences in intrinsic plasmid transfer efficiency, donor transfer efficiency, recipient receiving efficiency, or a combination of these factors. Even though the observed mobile elements were all classified as plasmids, we still expect that phages are an important contributor to HGT. However, as illustrated by the recording of phage M13, our system is not optimal for detecting invading phages as CRISPR spacer adaptation requires active growth of the recording cell19, which is often impaired upon phage infection. In addition, infection with phages can lead to cell lysis and subsequent loss of recording cells from the population. Furthermore, it is not clear what the expected concentration of E. coli targeting phages is in human fecal samples. Previous studies indicate that plaque forming units (pfu) from human feces on E. coli is in the range of 101107 per gram, with a median concentration of ~103 per gram42,43. Considering that the concentration of E. coli in human feces is in the range of 107109per gram44, interactions between phages and the recording strain might be substantially less common than interactions between commensal E. coli and the recording strain. Washing of the fecal sample (i.e., to remove antibiotics and other factors that can inhibit the recording strain) likely also contributed to the loss of phage particles. Lastly, as E. coli is not naturally competent, we are not able to detect naked environmental DNA. Consequently, our recording strain is best suited for detecting plasmid transfers. When our approach is applied to clinical fecal specimens, we were able to identify active DNA transfer in 22% of the samples (6 out of 27). It is difficult to evaluate whether the frequency of observed HGT in the fecal samples (22%) is limited by the methodology or whethe.

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What are the strongest arguments for considering fraternal twins with different skin colors as belonging to different races? Does genetics really matter in how people perceive race? What meanings do you attach to the idea of "race"? How do you think public categorizations and assumptions about "race" might affect the personal identities of twins such as Kian and Remee(twins born with different skin colors)?.

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What are the arguments for and against giving money to the people of Savannah for the massive fire that destroyed their city in 1796? Who has the better arguments? Why? House of Representatives, Relief to Savannah 1. Mr. W. Smith wished the House to resolve itself into a Committee of the Whole on the resolution, which he had the other day laid upon the table, proposing to afford some relief to the sufferers by the late fire at Savannah. For his part, he said, he could see no reasonable objection which could be made to so benevolent a proposition. A gentleman in the House had got a plan of the ruins of the city; it was, indeed, a most distressful scene. There had never occurred so calamitous an event of the kind in the United States, or which had so strong a claim upon the General Government for relief. He said they had granted assistance to the sufferers by fire at St. Domingo; and surely if it were justifiable to grant relief to foreigners in distress, it was at least equally so when the objects were our own citizens. If gentlemen had objections to the measure, he wished they would state them. The sum with which he should think of filling up the blank would not be such as to materially affect our finances. 2. [Mr. Macon:] The sufferings of the people of Savannah were doubtless very great; no one could help feeling for them. But he wished gentlemen to put their finger upon that part of the Constitution which gave that House power to afford them relief. Many other towns had suffered very considerably by fire. He believed he knew one that had suffered more than Savannah in proportion to its size: he alluded to Lexington in Virginia, as every house in the place was burnt. If the United States were to become underwriters to the whole Union, where must the line be drawn when their assistance might be claimed? Was it when three-fourths or four-fifths of a town was destroyed, or what other proportion? Insurance offices were the proper securities against fire. If the Government were to come forward in one instance, it must come forward in all, since every sufferer's claim stood upon the same footing. The sum which had been given to the sufferers at St. Domingo was to be charged to the French Republic, and that given to Count de Grasse's daughters was in consideration of their father's services. But New York had as great right to come forward and expect relief as Savannah. He felt for the sufferers in all these cases, but he felt as tenderly for the Constitution; he had examined it, and it did not authorize any such grant. He should, therefore, be very unwilling to act contrary to it. 3. Mr. Rutherford said, he felt a great deal of force on what gentlemen had said. There were two circumstances which were perfectly conclusive in his mind. He saw it our duty to grant relief from humanity and from policy. Savannah was a city of a minor, helpless State; it was a very young State, yet it was a part of the Union, and as such, was as much entitled to protect.

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