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VAGINAL DISCHARGE
TRICHOMONAS VAGINALIS
INTRODUCTION:
• Most common parasitic cause of STD
• Females are commonly affected than males
• Increase risk of HIV infection
MORPHOLOGY:
• Pear shaped
• Jerky or twitching motility on saline mount
• Bears 5 flagella
4 anterior flagella
1 lateral flagellum attached to undulating membrane
• Resides in :
Females – Vagina and urethra
Male- Urethra, seminal vesicle and prostate
CLINICAL FEATURE:
• 25-50% infections are asymptomatic
• Discharge- Profuse
Foul smelling
Greenish Yellow Frothy Discharge
• On colposcopy- small punctate hemorrhagic spots on
vagina and cervix (colpitis macularis)
seen in 2% cases only
GREEN YELLOW FROTHY DISCHARGE COLPOSCOPY
• In chronic infection
Vaginal discharge is scanty
Dysparenia present
• Complications
Pyosalpinx
Endometritis
Infertility
Preterm labour
• Trichomonas vaginalis can also cause non
gonococcal urethritis in womens
• In males: common features are non gonococcal urethritis
Other rare features are epididymitis, prostitis
and penile ulcers
DIAGNOSIS:
• DIRECT MICROSCOPY:
1. WET MOUNT: jerky motile trophozoites are visible
2. PERMANENT STAIN : geimsa and papanicolaou stain
• CULTURE:
1. Gold standard
2. High specificity and sensitivity
3. Commonly used culture media – diamond trypticase
yeast maltose media
• Antigen detection in vaginal secretion-
1. Rapid ICT
2. ELISA
• Antibody detection
• Moleculer method
• OTHER SUPPORTIVE TESTS:
1. Raised vaginal ph (>4.5)
2. Positive whiff test
TREATMENT (CDC)
• Recommended Regimen
• Metronidazole 2 g orally in a single dose
OR
• Tinidazole 2 g orally in a single dose
TREATMENT(NACO)
TRICHOMONIASIS

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TRICHOMONIASIS

  • 2. INTRODUCTION: • Most common parasitic cause of STD • Females are commonly affected than males • Increase risk of HIV infection
  • 3. MORPHOLOGY: • Pear shaped • Jerky or twitching motility on saline mount • Bears 5 flagella 4 anterior flagella 1 lateral flagellum attached to undulating membrane
  • 4. • Resides in : Females – Vagina and urethra Male- Urethra, seminal vesicle and prostate
  • 5. CLINICAL FEATURE: • 25-50% infections are asymptomatic • Discharge- Profuse Foul smelling Greenish Yellow Frothy Discharge • On colposcopy- small punctate hemorrhagic spots on vagina and cervix (colpitis macularis) seen in 2% cases only
  • 6. GREEN YELLOW FROTHY DISCHARGE COLPOSCOPY
  • 7. • In chronic infection Vaginal discharge is scanty Dysparenia present • Complications Pyosalpinx Endometritis Infertility Preterm labour
  • 8. • Trichomonas vaginalis can also cause non gonococcal urethritis in womens • In males: common features are non gonococcal urethritis Other rare features are epididymitis, prostitis and penile ulcers
  • 9. DIAGNOSIS: • DIRECT MICROSCOPY: 1. WET MOUNT: jerky motile trophozoites are visible 2. PERMANENT STAIN : geimsa and papanicolaou stain • CULTURE: 1. Gold standard 2. High specificity and sensitivity 3. Commonly used culture media – diamond trypticase yeast maltose media
  • 10. • Antigen detection in vaginal secretion- 1. Rapid ICT 2. ELISA • Antibody detection • Moleculer method • OTHER SUPPORTIVE TESTS: 1. Raised vaginal ph (>4.5) 2. Positive whiff test
  • 11. TREATMENT (CDC) • Recommended Regimen • Metronidazole 2 g orally in a single dose OR • Tinidazole 2 g orally in a single dose