2. Animal Welfare
•Animal welfare is defined as the well being of
animals.
•Respect for animal welfare is often based on the belief
that non-human animals are sentient and that
consideration should be given to their well-
being or suffering, especially when they are under the
care of humans.
3. Where experiments on animals
are usually done ?
• In Universities,
• Medical schools,
• Pharmaceutical companies,
• Farms,
• Defense establishments,
Commercial facilities that provide
animal-testing services to industry.
4. Groups which are against the use of animals in experiments
• PETA--- for animal welfare--- ( People for the Ethical Treatment
of Animals)
• BUAV— for animal rights--- ( British Union for the Abolition of
Vivisection )
• BUAV is a British animal protection and
advocacy group that campaigns for the
abolition of all animal experiments.
5. HISTORY OF ANIMAL EXPERIMENTS
Galen, a physician
in 2nd-century
Rome, dissected
pigs and goats,
and is known as
the "father of
vivisection."
6. Types of vertebrates used in animal testing
in Europe in 2005: a total of 12.1 million
animals were used
7. INSTITUTIONAL ANIMAL ETHICS
COMMITTEE(IAEC)
A body comprising of a group of persons recognized and
registered by the CPCSEA performed in an establishment
which is constituted and operated in accordance with
procedures specified for the purpose by the Committee.
A number of animals are used every year in research.
8. ROLE OF IAEC
• To protect the rights on animals laws
were passed.
• To implement and monitor the laws ----
committee were set up like CPCSEA
(Committee for the Purpose of Control
and Supervision of Experiments on
Animals) and under its supervision IAEC
etc.
9. IAEC Constitution
• CPCSEA constitutes the IAEC on receipt of five (5)
names:
• And nominate four (4) names from outside the institute.
• IAEC duration: 5 years
• And is required to be reconstituted at the time of renewal
of registration.
10. IAEC Composition
• From within Institute:
Biological scientist 1
Scientists from different biological discipline 2
A Veterinarian from care of animals 1
Scientist-in-Charge of AH Facility 1
The Chairperson of the Committee and Member Secretary would be
nominated by the Institution
• From CPCSEA
Main nominee 1
Link nominee 1
Scientist from outside 1
Socially Aware Nominee 1
11. Functions of CPCSEA:
• Registration of establishments conducting animal experimentation or
breeding of animals.
• Selection and appointment of nominees in the Institutional Animal Ethics
Committees of registered establishments.
• Approval of Animal House Facilities on the basis of reports of
inspections conducted by CPCSEA.
• Permission for conducting experiments involving use of animals.
• Recommendation for import of animals for use in experiments.
• Action against establishments in case of violation of any legal
norm/stipulation.
12. THE PREVENTION OF CRUELTY TO
ANIMALS (PCA) ACT, 1960
The PCA act is an act of parliament of India enacted in 1960 to prevent
the infliction of unnecessary pain or suffering on animals and to amend
the laws relating to the prevention of cruelty to animals.
CHAPTER I – PRELIMINARY
CHAPTER II - ANIMAL WELFARE BOARD OF INDIA
CHAPTER III-CRUELTY TO ANIMALS GENERALLY
CHAPTER IV-EXPERIMENTATION OF ANIMALS
CHAPTER V-PERFORMING ANIMALS
CHAPTER VI-MISCELLANEOUS
13. ROLE OF ANIMAL WELFARE IN PRECLINICAL TESTING:
• Animal research is extremely beneficial in minimising the risks to
humans in clinical trials designed to find new and more effective
therapies and diagnostic tests to treat serious diseases and improve
the quality of patients’ lives.
• Advances in research on complex diseases such as cancer,
Alzheimer’s disease or Parkinson’s disease heavily depend on the
use of animal models.
• Approximately 70% of severe adverse effects that would occur in
humans are identified during the animal testing stage.