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INFECTIVE ENDOCARDITIS
Mr.Veerabhadra .B B
Asst Lecturer
Medical-Surgical Nursing dept.
DEFINITION:
Endocarditis is an inflammatory processes of
the endocardium , heart valves, or cardiac
prosthesis .
Causative agent:
*Bacterial (eg, streptococci, enterococci,
pneumococci, staphylococci).
*Fungal & rickettsiae
Endocarditis (also known as infective or
bacterial endocarditis)
RISK FACTORS
 Dental Procedure.
 Genito urinal Procedure.
 Intra venous injection.
 Aging.
 Altered immunity.
 Systemic infection.
 Drug induced : Immunosuppressive medications or
corticosteroids
PATHOPHYSIOLOGY
Due to etiological factor bacteria enter into blood stream
Colonization, replication of bacteria on valve leaflets
Bacteria get surrounds by fibrin and platelets
Forms vegetation and clots travel to other organs, forming abscesses.
Damage heart valves by perforating and deforming valve leaflet
Causes infarction of organs in heart, kidneys, spleen or lungs.
CLINICALMANIFESTATIONS
Findings are non- specific and can involve multiple
organ systems
1)Fever- occurs in 90% patients
2)Non specific manifestations includes -fever
with chills, malaise, weakness, fatigue,
anorexia
-arthralgias, myalgias, back pain, abdominal discomfort,
weight loss, headache and clubbing of fingers
CONTD…
3) Vascular manifestations includes
a. Splinter hemorrhages in nail beds
b. petechiae- bleeding in conjunctiva and lips, bucal
mucosa, ankles and feet.
c. Oster notes-painful, tender
d. Janeways lesion- flat, painless, small red spots on
palms and sole.
e. Roths spots- hemorrhage in retinal lesions.
PETECHIAE- BLEEDING IN
CONJUNCTIVA
Splinter hemorrhages in
nail beds
Petechiae in bucal mucosa
ROTHS SPOTS
Janeways lesion
Fundoscopic examination of
eye showing Roths Spot
CONTD…
4) Cardiacmanifestations-
a) Heart murmur with aortic and mitral valve most
commonly affected
5) Secondary toembolisation-
*Embolisation in spleen- sharp, at upper quadrant pain
and spleenomegaly, local tenderness
* Kidney- pain in the flank, hematuria, glomeruli
nephritis.
* Brain- hemiplegia, ataxia, aphasia, visual changes and
change in level of consciousness.
* Pulmonaryemboli.
DIAGNOSTIC STUDIES:
 History collection: H/o any invasive procedure.
 Physical Examination : Sign & symptoms
 Blood culture , RFT, LFT & complete Hemogram.
 ECG To rule out any other H/o of MI, Arrhythmia
 Echocadiogram. (To check valve function)
 Chest X-ray.
MEDICALMANAGEMENT
The medical management includes
For bacterial infection treated with
 Penicillin G (At 12-18 Million/d IV By in 6 equally divided
doses for 4 weeks.)
 vancomycin (at 30mg/kg/dl IV in 2 equally divided doses for 4
weeks.)
 Ceftriaxone at 2 g/d IV for 4 weeks.
 Gentamycin at 1mg/kg every 8 hours for 2 weeks
CONT……
 For fungal infections
Antifungal :Amphoterician-B , Abelect,Amphocin
 Fever: Aspirin or acetaminophen.
 Adequate rest
 Sufficient fluid intake.
 Prophylactic treatment for high-risk
individuals.
SURGICAL MANGEMENT
 Replacement of diseased valve.
Aortic or mitral valve Replacement.
 Corrective surgery if refractory heart
failure develops or heart structures
are damaged .
NURSING MANAGEMENT
 Provide Adequate rest.
 Provide assistant in physically demanding
activities.
 To reduce anxiety, allow the patient to express his
concerns .
 Before giving an antibiotic, obtain a patient history
of allergies.
 Assess cardiovascular status( Murmur, ECG)
frequently,
 Administer oxygen to ensure adequate
oxygenation.
 Monitor the patient’s renal status .
THANK YOU
Take Care of Your Heart

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Endocarditis

  • 1. INFECTIVE ENDOCARDITIS Mr.Veerabhadra .B B Asst Lecturer Medical-Surgical Nursing dept.
  • 2. DEFINITION: Endocarditis is an inflammatory processes of the endocardium , heart valves, or cardiac prosthesis . Causative agent: *Bacterial (eg, streptococci, enterococci, pneumococci, staphylococci). *Fungal & rickettsiae Endocarditis (also known as infective or bacterial endocarditis)
  • 3. RISK FACTORS  Dental Procedure.  Genito urinal Procedure.  Intra venous injection.  Aging.  Altered immunity.  Systemic infection.  Drug induced : Immunosuppressive medications or corticosteroids
  • 4. PATHOPHYSIOLOGY Due to etiological factor bacteria enter into blood stream Colonization, replication of bacteria on valve leaflets Bacteria get surrounds by fibrin and platelets Forms vegetation and clots travel to other organs, forming abscesses. Damage heart valves by perforating and deforming valve leaflet Causes infarction of organs in heart, kidneys, spleen or lungs.
  • 5. CLINICALMANIFESTATIONS Findings are non- specific and can involve multiple organ systems 1)Fever- occurs in 90% patients 2)Non specific manifestations includes -fever with chills, malaise, weakness, fatigue, anorexia -arthralgias, myalgias, back pain, abdominal discomfort, weight loss, headache and clubbing of fingers
  • 6. CONTD… 3) Vascular manifestations includes a. Splinter hemorrhages in nail beds b. petechiae- bleeding in conjunctiva and lips, bucal mucosa, ankles and feet. c. Oster notes-painful, tender d. Janeways lesion- flat, painless, small red spots on palms and sole. e. Roths spots- hemorrhage in retinal lesions.
  • 7. PETECHIAE- BLEEDING IN CONJUNCTIVA Splinter hemorrhages in nail beds Petechiae in bucal mucosa
  • 8. ROTHS SPOTS Janeways lesion Fundoscopic examination of eye showing Roths Spot
  • 9. CONTD… 4) Cardiacmanifestations- a) Heart murmur with aortic and mitral valve most commonly affected 5) Secondary toembolisation- *Embolisation in spleen- sharp, at upper quadrant pain and spleenomegaly, local tenderness * Kidney- pain in the flank, hematuria, glomeruli nephritis. * Brain- hemiplegia, ataxia, aphasia, visual changes and change in level of consciousness. * Pulmonaryemboli.
  • 10. DIAGNOSTIC STUDIES:  History collection: H/o any invasive procedure.  Physical Examination : Sign & symptoms  Blood culture , RFT, LFT & complete Hemogram.  ECG To rule out any other H/o of MI, Arrhythmia  Echocadiogram. (To check valve function)  Chest X-ray.
  • 11. MEDICALMANAGEMENT The medical management includes For bacterial infection treated with  Penicillin G (At 12-18 Million/d IV By in 6 equally divided doses for 4 weeks.)  vancomycin (at 30mg/kg/dl IV in 2 equally divided doses for 4 weeks.)  Ceftriaxone at 2 g/d IV for 4 weeks.  Gentamycin at 1mg/kg every 8 hours for 2 weeks
  • 12. CONT……  For fungal infections Antifungal :Amphoterician-B , Abelect,Amphocin  Fever: Aspirin or acetaminophen.  Adequate rest  Sufficient fluid intake.  Prophylactic treatment for high-risk individuals.
  • 13. SURGICAL MANGEMENT  Replacement of diseased valve. Aortic or mitral valve Replacement.  Corrective surgery if refractory heart failure develops or heart structures are damaged .
  • 14. NURSING MANAGEMENT  Provide Adequate rest.  Provide assistant in physically demanding activities.  To reduce anxiety, allow the patient to express his concerns .  Before giving an antibiotic, obtain a patient history of allergies.  Assess cardiovascular status( Murmur, ECG) frequently,  Administer oxygen to ensure adequate oxygenation.  Monitor the patient’s renal status .
  • 15. THANK YOU Take Care of Your Heart