The document is a curriculum vitae for Travis Owen Gurney that details his education, work experience, publications, presentations, and activities. He received a B.A. in Biology from The Ohio State University and has worked in various research roles at the Dorothy M. Davis Heart and Lung Research Institute since 2008. He has over 10 peer-reviewed publications and numerous conference presentations and is currently a Laboratory Manager/Research Associate.

1. CURRICULUM VITAE
Travis OwenGurney Position Title:
Laboratory Manager/Research Associate
Dorothy M Davis Heart and Lung Research Institute
College of Medicine - Division of Pulmonary,
Allergy, Critical Care and Sleep Medicine
Email: gurney.16@osu.edu
Cell Phone: (330)-354-1364
1103 Englewood Ave. Durham, NC 27701
Education:
The Ohio State University - Columbus, OH
B.A. Biology (Pre-Health Sciences) - June, 2012
Experience:
Student Research Assistant - Dr. Parinandi Group - Dorothy M. Davis Heart and Lung Research Institute
Internal Medicine - Division of Pulmonary, Allergy, Critical Care and Sleep Medicine
(Spring 2008 - Spring 2012)
Manager - CORE Microscopy Lab - Dorothy M. Davis Heart and Lung Research Institute
DHLRI CORE Facilities (Spring 2010 – Fall 2015)
Lab Manager/Research Associate - Dr. Parinandi Group - Dorothy M. Davis Heart and Lung Research Institute
Internal Medicine - Division of Pulmonary, Allergy, Critical Care and Sleep Medicine
(Spring 2012 – Fall 2014)
Research Assistant - Dr. Weisleder Group – Dorothy M. Davis Heart and Lung Research Institute
College of Medicine – Department of Physiology and Cell Biology
(Fall 2014 – Fall 2015)
Peer-Reviewed Publications:
1. Patel RB, Kotha SR…Gurney TO (5/10)… Parinandi NL. Pulmonary fibrosis inducer, bleomycin,
causes redox-sensitive activation of phospholipase D and cytotoxicity through formation of bioactive
lipid signal mediator, phosphatidic acid, in lung microvascular endothelial cells. Int J Toxicol. 2011
Feb;30(1):69-90. PMID: 21131602 (Image made Journal Cover page)
2. Sliman SM, Patel RB…Gurney TO (8/10)… Parinandi NL. Adiponectin Protects Against Hyperoxic
Lung Injury and Vascular Leak Cell. Biochem Biophys. 2011 Dec 20. PMID: 22183615
3. Secor JD, Kotha SR, Gurney TO… Parinandi NL. Novel lipid-soluble thiol-redox antioxidant and
heavy metal chelator, N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) and phospholipase D-specific
inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling
leading to protection against cytotoxicity in aortic endothelial cells. Int J Toxicol. 2011 Dec;30(6):619-
38. Epub 2011 Oct 12. PMID: 21994240
4. Patel RB, Kotha SR…Gurney TO (5/11)…Parinandi NL. Thiol-redox antioxidants protect against lung
vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin:
comparison between classical thiol-protectant, N-acetyl-L-cysteine, and novel thiol antioxidant, N,N'-
bis-2-mercaptoethyl isophthalamide. Toxicol Mech Methods. 2012 Jun;22(5):383-96. PMID: 22409285
5. Malireddy S, Kotha SR…Gurney TO (4/8)…Parinandi NL. Phytochemical antioxidants modulate
mammalian cellular epigenome: implications in health and disease. Antioxid Redox Signal. 2012 Jul
15;17(2):327-39. PMID: 22404530

2. 6. Hinzey AH, Kline MA…Gurney TO (7/8)… Parinandi NL. Choice of cyclodextrin for cellular
cholesterol depletion for vascular endothelial cell lipid raft studies: cell membrane alterations,
cytoskeletal reorganization and cytotoxicity. Indian J Biochem Biophys. 2012 Oct;49(5):329-41. PMID:
23259319
7. Kotha SR, Gurney TO… Parinandi NL. Mitochondrial lipid peroxidation in lung damage and disease.
Mitochondrial Function in Lung Health and Disease. Book Chapter: Springer Science, Nov. 2013.
8. Huang LS, Mathew B…Gurney TO (17/21)… Natarajan V. The Mitochondrial Cardiolipin-
Remodeling Enzyme Lysocardiolipin Acyltransferase (LYCAT) is a novel target in pulmonary fibrosis.
American Journal of Critical Care and Respiratory Medicine “Blue Journal”. 2014 Jun 1;189(11):1402-
15. PMID: 24779708
9. Kotha SR, Secor JD, Gurney TO… Parinandi NL. Angiotensin-II-induced vascular smooth muscle cell
proliferation is mediated by phosphatidic acid: Role of ERK-regulated phospholipase-D signaling.
Molecular Biology Reports “Springer”. In Review, Submitted 2015.
10. Gurney TO, Kotha SR, Sliman SM… Parinandi NL. Hyperglycemic oxoaldehyde-induced vascular
endothelial cell damage is protected by dimercaptosuccinic acid: Role of iron. Molecular Cellular
Biochemistry. In Submission Fall 2015.
11. Vala A*,Gurney TO*, Kotha SR… Parinandi NL. Mercury induces tight junction alterations and
paracellular transport in colon epithelial cells through oxidative stress and thiol-redox dysregulation –
Protection by novel lipid-soluble thiol antioxidant and heavy metal chelator, N,N’-bis-2-
(mercaptoethyl)isophthalamide (NBMI). International Journal of Toxicology (IJOT). In Submission Fall
2015. *Equally Contributed
Published Abstracts:
1. Hyperglycemic Carbonyl Stress in Vascular Endothelial Cells and Protection by Heavy Metal Chelators
– SFRBM 2010 (Society for Free Radical and Biological Medicine)
2. Pulmonary Oxygen Toxicity Protection by Adiponectin - SFRBM 2010 (Society for Free Radical and
Biological Medicine)
3. Hyperglycemic Carbonyl Stress in Vascular Endothelial Cells and Protection by Heavy Metal Chelators
– NCUR 2011 (National Conference for Undergraduate Research)
4. Polyunsaturated Fatty Acids Suppress Adiponectin Secretion By Adipocytes – SFRBM 2012 (Society
for Free Radical and Biological Medicine)
5. Phytochemical Lipoxygenase Inhibitor, Baicalein, Induces Bioactive Phospholipid Signal Mediator
Generation in Lung Vascular Endothelial Cells - ATS 2013 (American Thoracic Society)
6. Fatty Acids Down Regulate and Inhibit Secretion of Adiponectin in Adipocytes through Oxidative
Stress – ATS 2013 (American Thoracic Society)
7. Glucose-derived Carbonyl during Diabetes Causes Lung Vascular Endothelial Dysfunction through
Phospholipase A2 Activation and Cytoskeletal Alterations - ATS 2013 (American Thoracic Society)

3. Presentations:
Spring 2009 - Denman Undergraduate Research Forum – Ohio State University Campus, Columbus, OH
Fall 2009 - Pulmonary Research Day – Ohio State University Medical Center, Columbus, OH
Fall 2009 - DHLRI Research Day - Ohio State University Medical Center, Columbus, OH
Spring 2010 - Denman Undergraduate Research Forum – Ohio State University Campus, Columbus, OH
Fall 2010 - Pulmonary Research Day – Ohio State University Medical Center, Columbus, OH
Fall 2010 - Society for Free Radical and Biological Medicine (SFRBM), Orlando, Fl
Fall 2010 - Society of Toxicology (SOT), Washington D.C.
Fall 2010 - DHLRI Research Day - Ohio State University Medical Center, Columbus, OH
Received 1st Place Undergraduate Award
Spring 2011 - National Conference for Undergraduate Research (NCUR), Ithaca, NY
Spring 2011 - Denman Undergraduate Research Forum – Ohio State University Campus, Columbus, OH
Spring 2012 - Translational to Clinical Care Wound Healing Conference (T2C), Columbus, OH
Fall 2012 - Society for Free Radical and Biological Medicine (SFRBM), San Diego, CA
Spring 2013 - College of Medicine and JNM Hospital WBUHS, Kolkata, India
Invited Speaker, Provided Honorarium
Spring 2013 - American Thoracic Society - Philadelphia, PA
Institutional and Divisional Activities:
-Laboratory Manager of DHLRI Microscopy CORE:
a. Responsible for operation and training on Zeiss LSM 510 Confocal Microscope and Nikon E-800
Fluorescent Microscope
b. Maintain and operate the Coherent Verdi V-10 Multi-Photon IR Laser
-Member of DHLRI Shared Equipment Committee (Summer 2013 – Fall 2015)
-Equipment Coordinator for DHLRI 6th Floor:
a. Facilitate maintenance and repair of shared equipment on designated university assets
b. Properly instruct users on operation of shared university assets.
-Radiation Supervisor for DHLRI 6th Floor:
a. Responsible for all formal training, storage, disposal, and emergencies
b. Assist in the acquisition of new permits and restructuring of radioactive licenses
-Responsible for maintaining lab standard practices for BSL-2, IACUC, and Radiation approved laboratories
-DHLRI 640, DHLRI 616, DHLRI 480, DHLRI 180A
Clinical Research:
-Member of Sickle Cell Research Team in the Division of Hematology at Ohio State University
-Part of investigation team for ongoing human clinical trials with Division of Hematology:
a. Study to assess safety and impact of selG1 with or without hydroxyurea therapy in sickle cell disease
patients with pain crisis (SUSTAIN) PI: Dr. Desai, MD Sponsor: Selexys Pharmaceuticals
b. Association of red blood cell alloimmunization with inflammation in sickle cell disease
PI: Dr. Desai, MD
c. Lipidomic Profilers of blood and blood constituents of normal and sickle cell individuals
PIs: Dr. Kraut, MD, Dr. Parinandi, Ph.D.
-Part of investigation team for ongoing human clinical trials with Division of Immunology and Transplant
Medicine at Ohio State University
a. Contribution to membrane repair to the progression of Dermatomyositis and Polymyositis
PIs: Dr. Jarjour, MD, Dr. Weisleder, Ph.D.
b. A study of the membrane repair protein complex in the human renal epithelial cells following ischemic
damage
PIs: Dr. Nori, MD, Dr. Weisleder, Ph.D.

4. Academic Involvement:
-Mentoring and training undergraduate and graduate students in the greater Columbus, OH area
-Assist with course preparation and examinations at the graduate and undergraduate level
-Assist in activities for The Ohio State University Undergraduate Research Organization (URO)
-Annual participation in the State of Ohio Science Olympiad and “Science Week” for Columbus, OH Middle
Schools
Editorial Activities:
-Reviewing Manuscripts for the Journal of Oxidative Medicine and Cellular Longevity
Membership in Scientific Associations:
-Member of the Society of Free Radical Biology and Medicine (SFRBM)
-Member of the American Heart Association (AHA)
-Member of the American Thoracic Society (ATS)
-Member of the Society of Toxicology (SOT)
References:
Dr. Narasimham Parinandi, Ph.D.
Narasimham.Parinandi@osumc.edu
(614)-204-9463
Dr. Noah Weisleder, Ph.D.
Noah.Weisleder@osumc.edu
(614)-292-5321
Dr. Thomas Hund, Ph.D.
Thomas.Hund@osumc.edu
(614)-292-0755