Introduction to study on hemophilia

1. STUDY OF HEMOPHILA
By
Saraf Sumit Kishor

2. INTRODUCTION
• Hemophilia is disease cause due to deficiency of vitamin k
in the body.
• The disease is transfer form parent to the children and the
rate of causing disease is low but the blood clotting factor
are not done proper function and the gene responsible for
the Hemophilia by using computational approach.
• When coagulation factors are missing or deficient the blood
does not clot properly and bleeding continues.
• Patients with Hemophilia A or B have a genetics defect
which results in a deficiency in one of the blood clotting
factors.

3. HEMOPHILIA
• Hemophilia is caused by an inherited genetic mutation.
• It mainly affected males due to the way it is passed from
a parent to their child.
• Chromosomes are the block of DNA. They contain a
detailed set of instruction that control a wide range of
factor, including how the body cells develop and the
body sex.

4. TYPES OF HEMOPHILIA
• Hemophilia A :
It is a recessive X- linked genetic disorder involving a
lack of functional clotting factor VIII and represents 80%
of hemophilia cases.
• Hemophilia B :
It is a recessive X- linked genetic disorder involving a
lack of functional clotting factor IX. It comprises
approximately 20% of hemophilia cases.

5. • Hemophilia C :
It is an autosomal disorder ( I.e. not X-linked) involving a lack of
clotting factor XI. Hemophilia C is not completely recessive, as
heterozygous individuals also show increased bleeding.
TYPES OF HEMOPHILIA

6. ACKNOWLEDGEMENT
I am grateful that I have been given this
opportunity to present my communication
skills. I would like to thank all the authorities
of the course on “Academic Writing”
conducted by UGC in coordination with
SWAYAM. It has helped me make my ideas
clear about writing a research paper. I would
also like to thank all the professors for clear
and understandable lectures provided by them
during the course.