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Understanding Migraines: A Nervous System Disease
- 1. MIGRAINES THANK YOU IN ADVANCE FOR TAKING THE TIME AND REVIEWING MY PRESENTATION
- 2. MIGRAINE IS A NERVOUS SYSTEM DISEASE PRIOR TO OUR UNDERSTANDING OF MIGRAINES, IT WAS THOUGHT TO BE CAUSED BY BLOOD VESSEL DEFECTS WITH IMPROVED TECHNOLOGIES AND PRACTICES TO ANALYZE OUR BRAIN (FMRIS AND PET SCANS) WE DISCOVERED THE ROOT CAUSES OF MIGRAINES ARE IN THE CENTRAL NERVOUS SYSTEM
- 3. PARTS OF THE NERVOUS SYSTEM & FUNCTIONS AFFECTED BY MIGRAINES
- 4. CALCIUM ION CHANNELS PEOPLE WITH MIGRAINE HAVE DEFECTIVE CALCIUM CHANNELS. THESE RECEPTORS DO NOT CLOSE COMPLETELY WHICH RESULTS IN TOO MUCH CALCIUM GETTING INSIDE THE CELL THIS EXCESS CALCIUM RESULTS IN AN EXAGGERATED ELECTRICAL SIGNAL. THIS RESULTS IN AN OVERREACTION TO STIMULUS, ESSENTIALLY HYPERSENSITIVITY
- 5. GENETIC DEFECTS OF NERVE CELLS GENETIC INFORMATION SUCH AS; - HOW ARE NEUROTRANSMITTERS MADE - HOW ARE NEUROTRANSMITTERS RELEASED - HOW ARE NEUROTRANSMITTERS INACTIVATED, CAN BE DEFECTIVE IN PEOPLE WITH MIGRAINE MIGRAINE IS USUALLY A COMBINATION OF THESE DEFECTS HENCE THE SPECTRUM OF SYMPTOMS DIFFERNTIATING FROM PERSON TO PERSON
- 6. TRIGEMINA L NERVE TRIGEMINAL NERVE INNERVATES; FACIAL MUSCLES PARANASAL SINUSES TEETH THRESHOLD FOR DISTRESSING TRIGEMINAL NERVE AND CAUSING RADIATING PAIN ACROSS INNERVATED AREAS IS LOWERED AND THE AMPLITUDE OF PAIN IS ABNORMALLY HIGH IN PEOPLE WITH MIGRAINE
- 7. DURA MATER DURING A MIGRAINE ATTACK, BLOOD VESSELS IN DURA MATER DILATE AND CONTRACT. THIS MOTION INCREASES THE LIKELIHOOD OF A STROKE OVER TIME
- 8. HYPOTHALAMUS HYPOTHALAMUS IS AFFECTED THROUGH TRIGEMINOHYPOTHALAMIC TRACT (TRIGEMINAL NUCLEI - HYPOTHALAMUS TRACT) SYMPTOMS RESULTING IN HYPOTHALAMIC AFFECT CONTRIBUTES TO THE 'AURA' PHASE OF A MIGRAINE EXAMPLES OF SUCH AFFECT WOULD BE; MOOD CHANGES & FATIGUE & FOOD CRAVINGS
- 9. CORTICAL SPREADING DEPRESSION CORTICAL SPREADING DEPRESSION IS THE TERM USED FOR THE FEELING OF ACHING DURING A MIGRAINE ATTACK
- 10. WHAT IS CORTICAL SPREADING DEPRESSIO N? CORTICAL SPREADING DEPRESSION IS ESSENTIALLY AN ELECTRICAL WAVE SPREADING THROUGH THE SURFACE OF THE CORTEX
- 11. WHAT IS AFFECTED BY CORTICAL SPREADING DEPRESSION? VISUSAL SYSTEM - FLASHING LIGHTS - SENSITIVITY TO LIGHT OLFACTORY SYSTEM - ABNORMAL SMELLS PREFRONTAL CORTEX - FOGGY THINKING - DECREASED COGNITIVE CAPACITY
- 12. HOW HAS THIS COURSE HELPED ME TO ANALYZE PHENOMENO N AROUND ME? DURING THIS COURSE, I REALIZED YOU CAN ALWAYS APPROACH ANYTHING HUMAN RELATED WITH A NEUROBIOLOGICAL PERSPECTIVE. EVERYTHING WE ENGAGE IN WHETHER IT IS ACTION, PERCEPTION OR ANY INVENTION ACROSS THE HUMAN HISTORY CAN BE ANALYZED UNDER THE LENS OF NEUROBIOLOGY. I AM A DESIGN MAJOR BUT UNDERSTANDING HOW OUR BRAIN WORKS WAS A VALUE ADDED TO MY LIFE. ALSO, I DEVELOPED A SYMPATHY TO PEOPLE WITH DEBILITATING DISEASES. I WAS VERY DISTANT TO SUCH TRAGIC EVENTS PREVIOUSLY. I AM VERY GRATEFUL TO HAVE STUMBLED UPON THIS COURSE. I HOPE YOU ARE FEELING SIMILAR POSITIVE FEELINGS PEER :)