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The Cytoskeleton
Y.SHASHANK
17BCB015
3/11/2018 SHASHANK 1
What is Cytoskeleton?
Cytoplasm contains a complex network of
filaments and microtubules which form a
structural framework known as
CYT0SKELETON.
3/11/2018 SHASHANK 2
3/11/2018 SHASHANK 3
Cells need (cyto) skeleton to:
*create shape
*change shape
*allow movement
Cytoskeleton: The skeleton and muscle of a cell
3/11/2018 SHASHANK 4
Three main kinds of fibers make up
the CYTOSKELETON:
● MICROFILAMENT
● INTERMEDIATE FILAMENT
● MICROTUBULES
3/11/2018 SHASHANK 5
3/11/2018 SHASHANK 6
3/11/2018 SHASHANK 7
MICROFILAMENT
●Thinnest filament present in the cytoskeleton in
cytoplasm of eukaryotic cell.
●Give the cell its shape and enable cell movement
3/11/2018 SHASHANK 8
3/11/2018 SHASHANK 9
3/11/2018 SHASHANK 10
FUNCTIONS OF MICROFILAMENT
Microfilaments play a role in
structure,cell motility, and cell
division. Microfilaments are made
of actin, and thus are involved in
muscle contraction as well as cell
division.
3/11/2018 SHASHANK 11
INTERMEDIATE FILAMENTS
● Made of variety of proteins,
including keratin, desmin and
vimentin
● 8to 12 nanometer
● Composed of two anti
parallel dimer3/11/2018 SHASHANK 12
INTERMEDIATE FILAMENTS
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FUNCTIONS OF INTERMEDIATE FILAMENT
●provide mechanical support for
the plasma membranewhere it comes
into contact with other cells or with
the extracellular matrix
●intermediate filaments do not
participate in cell motility.
3/11/2018 SHASHANK 17
MICROTUBULES
●Microtubules, the thickest fibers, are hollow rods about 25 microns in diameter.
●Microtubule fibers are made up of the globular protein, tubulin, and they grow or shrink as more tubulin molecules are
added or removed.
3/11/2018 SHASHANK 18
MICROTUBULES
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3/11/2018 SHASHANK 21
3/11/2018 SHASHANK 22
FUNCTIONS OFMICROTUBULES
Microtubules participate in theintracellular
transport of organelles andvesicles.
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3/11/2018 SHASHANK 24
Microtubules are the centralstructural
supports in cilia andflagella.
Thelocomotive appendages ofcell
3/11/2018 SHASHANK 25
Cilia
●Minute hair like organelles, identical in structure
to flagella, that line the surfaces of certain cells and
beat in rhythmic waves, providing locomotion to
ciliate protozoan and moving liquids along internal
epithelial tissue in animals.
3/11/2018 SHASHANK 26
CILIA
3/11/2018 SHASHANK 27
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FLAGELLA
●A slender threadlike structure, esp. a microscopic
whip like appendage that enables many protozoa,
bacteria, spermatozoa, etc., to swim.
3/11/2018 SHASHANK 30
FLAGELLA
3/11/2018 SHASHANK 31
FLAGELLA
3/11/2018 SHASHANK 32
3/11/2018 SHASHANK 33
Thankyou….
-Y . Shashank
3/11/2018 SHASHANK 34

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Cytoskeleton