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Pediatric head injury in last 7 years:
  a hospital based epidemiological
   analysis from Andhra Pradesh




                     Dr. Shailendra Deepak Anjankar
Title: Pediatric head injury in last 7 years: a
 hospital based epidemiological analysis from
 Andhra Pradesh

Author : Dr. Shailendra Anjankar,

Guides: Dr. Subodh Raju, Dr. M. A. Jaleel,

                                   Dr. Dilnavaz B.




Department of Neurosurgery, Kamineni Hospital,
 L. B. Nagar, Hyderabad, A.P., India.
Outline
Introduction
Aim
Material and Methods
Results
Discussion
Conclusion
Which is a safer place?
THE WORLD IS FULL OF IDIOTS ! THINK FIRST AND FAST
Introduction
 Population of India
       (as on July 2011) :
  1,205,073,612
 In India, children
  between 1 to 14 years
  forms 29.7% of total
  population
                                   Reference: Thomas M.McDevitt and
  Reference: CIA world factbook.   Patricia M. Rowe, The United States in
  (Government organisation)        International Context: 2000, Census 2000
                                   Brief, C2KBR/01-11. U.S. Census Bureau,
                                   Washington, DC. (2002), p. 9.
The statistics from India are
                   chilling!
     At least 14 deaths per hour in 2008.
     The total annual deaths due to road accidents
     has crossed 1.18 lakh
     Of total road accident deaths in the country
     maximum are from Andhra Pradesh (12%),
     Maharashtra (11%) and Tamil Nadu (10.8%).
     The death rate per 10,000 vehicles in India is
     45 while it is only 3 in developed countries.
Reference : National Crime Records Bureau (NCRB), 2008 report.
Leading causes of death, WHO 2004
                2004                                  2030
Rank   Disease or Injury                Rank   Disease or Injury
1      Ischaemic heart disease          1      Ischaemic heart disease
2      Cerebrovascular disease          2      Cerebrovascular disease
3      Lower respiratory infections     3      COPD
4      COPD                             4      Lower respiratory infections
5      Diarrhoeal diseases              5      Road traffic injuries
6      HIV/AIDS                         6      Trachea, bronchus, lung cancer
7      Tuberculosis                     7      Diabetes mellitus
8      Trachea, bronchus, lung cancer   8      Hypertensive heart disease

9      Road traffic injuries            9      Stomach cancer

10     Prematurity & low-birth weight   10     HIV/AIDS
Reference : Faul M, Xu L, Wald MM, Coronado VG. Traumatic brain injury in the
United States: emergency department visits, hospitalizations, and deaths. Atlanta
(GA): Centers for Disease Control and Prevention, National Center for Injury
Prevention and Control; 2010.




Reference : Luerssen TG, Klauber MR, Marshall LF. Outcome from head injury related
to patient's age.A longitudinal prospective study of adult and pediatric head injury. J
Neurosurg. 1988;68:409–16.
Children are not little adult!
Children have greater disposition to head trauma:
    o Greater head mass relative to body weight ratio making
      them top-heavy
        Neck musculature has not been developed to handle
        relatively heavier structure
        Increased head weight results in increased momentum
        during falls or injuries

   o Brain area has more fluid: more susceptible to wave-
     like forces

   o Less myelination

   o
The Aim of this study:
is to analyze epidemiology of Pediatric head
injury with respect to Mode of accident,
Pediatric Trauma Score, GCS, Radiological and
laboratory analysis and its correlation with
GOS.
Material and methods
In this retrospective study, we included all
patients with TBI aged less than 12 years
admitted in our hospital, during last 7 year.
Our hospital is 350 bedded Tertiary care centre
on National Highway (NH-9).
Patients admitted were examined and scored
according to Glasgow coma scale(GCS) score on
arrival and underwent computed cerebral
tomography (CT) scan, X-ray Cervical-spine as
routine protocol, as soon as feasible.
The patients medical files were
retrospectively reviewed, and
the data was collected and
was recorded in Proforma.

Age, gender, vital signs,
socioeconomic status, mode
of injury, GCS score, pupil
response, motor deficit,
presence of LOC, vomiting,
convulsion, ENT bleed,
Peadiatric Trauma Score, Brain
CT-scan and X-ray C-spine
findings, Lab investigations,
use of mechanical ventilation,
number of ICU stay, need for
surgery, and outcome
analysed at discharge and
follow-up.
Collected data were analyzed using Microsoft Assess
software and results were tabulated and compared.
Statistical tools – averages and percentages.
Results
During the study period, 209 children were
admitted with TBI in our hospital were included
in the study.
There were only 4 (1.91%) infants,86 (41.15%)
were belonging to age group of 1-5 Yrs and 119
(56.94%) were of 6-12 Yrs. Majority 142
(67.94%)were boys and 67 (32.06%) were girls.
The major cause of head trauma was Road Traffic
Accident (59.81%) which included
  26.32% (55) RTA while Crossing the Road,
  15.79 % (33) while traveling on 2 wheeler as pillion rider
  7.66 % (16) while driving 2 wheeler,
  10.05 % (21) while traveling in 4 wheeler.
Second most common cause of head injury
was fall from height (21.53%), whereas 4.78%
had injury due to fall of TV set on head.
Mean Glasgow Coma Scale was 12+/- 3,
116 (63%) had mild head injury,
68 (25%) had moderate head injury and
25 children (12%) had severe head injury.
15.78% (33 children) presented with seizures
Most common was Loss of consciousness in 74.64
% (156 children) whereas Vomiting was present in
47.84% ( 100 children)
The median pediatric trauma score was 7.
Uni-variate analysis showed showed poor outcome
(GOS 1,2 and 3) in 80% (N=8) with PTS of < 0.
Bad outcome
                               Good outcome
         (GOS 1,2,3) in 8/10
                               (GOS 4,5) in 2/10


                                    GOS


PTS of
<0
Most common CT scan brain finding was fractures
seen in 86 (40.67%) children.
63 (29.67%) children had normal CT brain finding.
None of the children were found to have
associated cervical spine injury in our study
11% (23 children) required surgery for
traumatic brain injury in our study.
Mean serum sodium
   was 137 +/-5, potassium
   4.1 +/-0.6, hemoglobin
   was 10.4 +/- 1.7.
Laboratory               Mean value   +/- 2 SD
parameters
Blood Glucose ( mg/dl)   128          --

Serum Sodium (mEq/ L)    137          5

Serum Potassium          4.1          0.6
(mEq/L)

Hemoglobin (%)           10.4         1.7
Mean blood sugar level was 128.37 and high
blood sugar level was found to be associated
with poor GCS at the time of admission
Glasgow outcome scale was performed at
discharge showed good outcome (GOS=5) for
(87.08% ) 182 children.
There were only 6 (2.87%) mortalities observed
in our study.
Discussion
   Our study showed RTA as major cause of
   pediatric TBI, whereas other studies from India
   showed Fall as the most common cause.1-6
   Majority of study including ours shows male
   predominance.1-4
Reference:
1. Mahapatra AK. Head injury in children. In: Mahapatra AK, Kamal R, editors. A Text
Book of head Injury. Delhi: Modern Publ; 2004. pp. 156–70
2. Osmond MH, Brennan-Barnes M, Shephard AL. A 4- year review of severe pediatric
trauma in eastern Ontario: a descriptive analysis. J Trauma. 2002;52:8–12.
3. Lalloo R, vanAs AB. Profile of children with head injuries treated at the trauma unit
of red cross. S Afr Med J. 2004;94:544–6.
4. . Crankson SJ. Motor vehicle injuries in childhood: A hospital based study in Saudi
Arabia. Pediatr Surg Int. 2006;22:641–5.
5. Sambasivan M. Epidemeology-Pediatric head injuries. Neurol India. 1995;43:57–8.
6. Jennet B. Epidemeology of head injury. Arch Dis Child. 1998;78:403–6.
Fall of TV on head still remains the cause of
  Pediatric TBI, as also reported by Samson et
  al.7
  Younger age group/ Children fare better as
  also found in our study.8-11
Reference:
7. Samson SK, Nair PR, Baldia M, Joseph M. Television tip-over head injuries in
children. Neurol India 2010 Sep-Oct;58(5):752-5.
8. Alberico AM, Ward JD, Choi SC, et al.:Outcome after severe headi njury.
Relationship to mass lesions, diffuse injury, and ICP course in pediatric and adult
patients. J Neurosurg 67:648-656, 1987.
 9. Andrews B, Pitts LH: Functional recovery after traumatic transtentorial herniation.
Neurosurg 2:227-231, 1991.
10. Berger MS, Pitts LH, Lovely M, et al.: Outcome from a severe head injury in
children and adolescents. J Neurosurg 62:194-199, 1985.
11. Bruce DA, Schut L, Bruno LA, et al.: Outcome following severe head injuries in
children. J Neurosurg 48:679-688, 1978.
Factors associated with poor outcome include
   low GCS at admission and prolonged
   impairment of consciousness.12
   Hyperglycemia, and especially its persistance
   over time, appears to be an important
   negative prognostic factor. 13

References :
12. Luerssen TG. Acute traumatic cerebral injuries. In: Cheek WR eds.
Pediatric Neurosurgery. Philadelphia: W.B. Saunders, 1994;266–
278.
13. Chiaretti A, DeBenedictis R, Polidori G. Early post-traumatic seizures in children
with head injury. Childs Nerv Syst 2000 Dec; 16(12): 862-6.
Persistence of hypoxia on admission and CT
     scan finding of SAH, DAI, Brain edema are
     factors associated with poor outcome.14
     Pediatric trauma score of <0 have poor
     outcome as also seen in our study.15


Reference:
14. Munch E C, Bauhuf C, Horn P. et al Therapy of malignant intracranial hypertension
by controlled lumbar cerebrospinal fluid drainage. Crit Care Med 2001. 29976–981.981.
15. Campbell, John Creighton (2000). Basic trauma life support for paramedics and other
advanced providers. Upper Saddle River, N.J: Brady/Prentice Hall Health
Conclusion
Road traffic Accident is the major cause of
Pediatric mortality and morbidity in our
country, followed by Falls.
Need to follow “Start early, reach safely”
axiom.
India need to have “ThinkFirst For Kids
program” . And also support United Nations
“Decade of Action for Road Safety- 2011-
2020” theme.
The ThinkFirst For Kids program represents a
collaborative effort of educators, the ThinkFirst
National Injury Prevention Foundation, the National
Highway Traffic Safety Administration (NHTSA), the
American Academy of Pediatrics, the Peace Education
Foundation and professionals from the fields of
psychology and psychiatry.
The goal of the program is to increase knowledge and
awareness among children in grades 1-3 of the causes
and risk factors of brain and spinal cord injury, injury
prevention measures, and the use of safety habits.
The United Nations
General Assembly has
proclaimed the period
2011-2020 as the Decade
of Action for Road Safety,
“with a goal to stabilize
and then reduce the
forecast level of road traffic
fatalities around the world
by increasing activities
conducted at the national,
regional and global levels”.
Acknowledgement
Thankful to my Guides- Dr. Subodh Raju, Dr. M. A. Jaleel
To our Dean DNB- Dr. Q. Hassan
To Managing Director - Dr. Shashidhar Kamineni Sir and KHL, LB Nagar staff.

To my colleagues – Dr. Renuka Sharma, Dr. S. Ramesh. Dr. Harikishor Reddy
To Medical Records Section – Mr. Kishor,

To Pediatric and Neurosurgery department staff

To my wife – Dr. Sumedha Anjankar and my parents Dr. Deepak and Vidhya Anjankar

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Peaditric head injury Dr. shailendra

  • 1. Pediatric head injury in last 7 years: a hospital based epidemiological analysis from Andhra Pradesh Dr. Shailendra Deepak Anjankar
  • 2. Title: Pediatric head injury in last 7 years: a hospital based epidemiological analysis from Andhra Pradesh Author : Dr. Shailendra Anjankar, Guides: Dr. Subodh Raju, Dr. M. A. Jaleel, Dr. Dilnavaz B. Department of Neurosurgery, Kamineni Hospital, L. B. Nagar, Hyderabad, A.P., India.
  • 4. Which is a safer place?
  • 5. THE WORLD IS FULL OF IDIOTS ! THINK FIRST AND FAST
  • 6. Introduction  Population of India (as on July 2011) : 1,205,073,612  In India, children between 1 to 14 years forms 29.7% of total population Reference: Thomas M.McDevitt and Reference: CIA world factbook. Patricia M. Rowe, The United States in (Government organisation) International Context: 2000, Census 2000 Brief, C2KBR/01-11. U.S. Census Bureau, Washington, DC. (2002), p. 9.
  • 7. The statistics from India are chilling! At least 14 deaths per hour in 2008. The total annual deaths due to road accidents has crossed 1.18 lakh Of total road accident deaths in the country maximum are from Andhra Pradesh (12%), Maharashtra (11%) and Tamil Nadu (10.8%). The death rate per 10,000 vehicles in India is 45 while it is only 3 in developed countries. Reference : National Crime Records Bureau (NCRB), 2008 report.
  • 8.
  • 9.
  • 10. Leading causes of death, WHO 2004 2004 2030 Rank Disease or Injury Rank Disease or Injury 1 Ischaemic heart disease 1 Ischaemic heart disease 2 Cerebrovascular disease 2 Cerebrovascular disease 3 Lower respiratory infections 3 COPD 4 COPD 4 Lower respiratory infections 5 Diarrhoeal diseases 5 Road traffic injuries 6 HIV/AIDS 6 Trachea, bronchus, lung cancer 7 Tuberculosis 7 Diabetes mellitus 8 Trachea, bronchus, lung cancer 8 Hypertensive heart disease 9 Road traffic injuries 9 Stomach cancer 10 Prematurity & low-birth weight 10 HIV/AIDS
  • 11. Reference : Faul M, Xu L, Wald MM, Coronado VG. Traumatic brain injury in the United States: emergency department visits, hospitalizations, and deaths. Atlanta (GA): Centers for Disease Control and Prevention, National Center for Injury Prevention and Control; 2010. Reference : Luerssen TG, Klauber MR, Marshall LF. Outcome from head injury related to patient's age.A longitudinal prospective study of adult and pediatric head injury. J Neurosurg. 1988;68:409–16.
  • 12. Children are not little adult! Children have greater disposition to head trauma: o Greater head mass relative to body weight ratio making them top-heavy  Neck musculature has not been developed to handle relatively heavier structure  Increased head weight results in increased momentum during falls or injuries o Brain area has more fluid: more susceptible to wave- like forces o Less myelination o
  • 13. The Aim of this study: is to analyze epidemiology of Pediatric head injury with respect to Mode of accident, Pediatric Trauma Score, GCS, Radiological and laboratory analysis and its correlation with GOS.
  • 14. Material and methods In this retrospective study, we included all patients with TBI aged less than 12 years admitted in our hospital, during last 7 year. Our hospital is 350 bedded Tertiary care centre on National Highway (NH-9). Patients admitted were examined and scored according to Glasgow coma scale(GCS) score on arrival and underwent computed cerebral tomography (CT) scan, X-ray Cervical-spine as routine protocol, as soon as feasible.
  • 15. The patients medical files were retrospectively reviewed, and the data was collected and was recorded in Proforma. Age, gender, vital signs, socioeconomic status, mode of injury, GCS score, pupil response, motor deficit, presence of LOC, vomiting, convulsion, ENT bleed, Peadiatric Trauma Score, Brain CT-scan and X-ray C-spine findings, Lab investigations, use of mechanical ventilation, number of ICU stay, need for surgery, and outcome analysed at discharge and follow-up.
  • 16.
  • 17.
  • 18. Collected data were analyzed using Microsoft Assess software and results were tabulated and compared. Statistical tools – averages and percentages.
  • 19. Results During the study period, 209 children were admitted with TBI in our hospital were included in the study. There were only 4 (1.91%) infants,86 (41.15%) were belonging to age group of 1-5 Yrs and 119 (56.94%) were of 6-12 Yrs. Majority 142 (67.94%)were boys and 67 (32.06%) were girls.
  • 20. The major cause of head trauma was Road Traffic Accident (59.81%) which included 26.32% (55) RTA while Crossing the Road, 15.79 % (33) while traveling on 2 wheeler as pillion rider 7.66 % (16) while driving 2 wheeler, 10.05 % (21) while traveling in 4 wheeler.
  • 21.
  • 22. Second most common cause of head injury was fall from height (21.53%), whereas 4.78% had injury due to fall of TV set on head.
  • 23. Mean Glasgow Coma Scale was 12+/- 3, 116 (63%) had mild head injury, 68 (25%) had moderate head injury and 25 children (12%) had severe head injury.
  • 24. 15.78% (33 children) presented with seizures Most common was Loss of consciousness in 74.64 % (156 children) whereas Vomiting was present in 47.84% ( 100 children)
  • 25. The median pediatric trauma score was 7. Uni-variate analysis showed showed poor outcome (GOS 1,2 and 3) in 80% (N=8) with PTS of < 0.
  • 26. Bad outcome Good outcome (GOS 1,2,3) in 8/10 (GOS 4,5) in 2/10 GOS PTS of <0
  • 27. Most common CT scan brain finding was fractures seen in 86 (40.67%) children. 63 (29.67%) children had normal CT brain finding.
  • 28. None of the children were found to have associated cervical spine injury in our study 11% (23 children) required surgery for traumatic brain injury in our study.
  • 29. Mean serum sodium was 137 +/-5, potassium 4.1 +/-0.6, hemoglobin was 10.4 +/- 1.7. Laboratory Mean value +/- 2 SD parameters Blood Glucose ( mg/dl) 128 -- Serum Sodium (mEq/ L) 137 5 Serum Potassium 4.1 0.6 (mEq/L) Hemoglobin (%) 10.4 1.7
  • 30. Mean blood sugar level was 128.37 and high blood sugar level was found to be associated with poor GCS at the time of admission
  • 31. Glasgow outcome scale was performed at discharge showed good outcome (GOS=5) for (87.08% ) 182 children. There were only 6 (2.87%) mortalities observed in our study.
  • 32. Discussion Our study showed RTA as major cause of pediatric TBI, whereas other studies from India showed Fall as the most common cause.1-6 Majority of study including ours shows male predominance.1-4 Reference: 1. Mahapatra AK. Head injury in children. In: Mahapatra AK, Kamal R, editors. A Text Book of head Injury. Delhi: Modern Publ; 2004. pp. 156–70 2. Osmond MH, Brennan-Barnes M, Shephard AL. A 4- year review of severe pediatric trauma in eastern Ontario: a descriptive analysis. J Trauma. 2002;52:8–12. 3. Lalloo R, vanAs AB. Profile of children with head injuries treated at the trauma unit of red cross. S Afr Med J. 2004;94:544–6. 4. . Crankson SJ. Motor vehicle injuries in childhood: A hospital based study in Saudi Arabia. Pediatr Surg Int. 2006;22:641–5. 5. Sambasivan M. Epidemeology-Pediatric head injuries. Neurol India. 1995;43:57–8. 6. Jennet B. Epidemeology of head injury. Arch Dis Child. 1998;78:403–6.
  • 33. Fall of TV on head still remains the cause of Pediatric TBI, as also reported by Samson et al.7 Younger age group/ Children fare better as also found in our study.8-11 Reference: 7. Samson SK, Nair PR, Baldia M, Joseph M. Television tip-over head injuries in children. Neurol India 2010 Sep-Oct;58(5):752-5. 8. Alberico AM, Ward JD, Choi SC, et al.:Outcome after severe headi njury. Relationship to mass lesions, diffuse injury, and ICP course in pediatric and adult patients. J Neurosurg 67:648-656, 1987. 9. Andrews B, Pitts LH: Functional recovery after traumatic transtentorial herniation. Neurosurg 2:227-231, 1991. 10. Berger MS, Pitts LH, Lovely M, et al.: Outcome from a severe head injury in children and adolescents. J Neurosurg 62:194-199, 1985. 11. Bruce DA, Schut L, Bruno LA, et al.: Outcome following severe head injuries in children. J Neurosurg 48:679-688, 1978.
  • 34. Factors associated with poor outcome include low GCS at admission and prolonged impairment of consciousness.12 Hyperglycemia, and especially its persistance over time, appears to be an important negative prognostic factor. 13 References : 12. Luerssen TG. Acute traumatic cerebral injuries. In: Cheek WR eds. Pediatric Neurosurgery. Philadelphia: W.B. Saunders, 1994;266– 278. 13. Chiaretti A, DeBenedictis R, Polidori G. Early post-traumatic seizures in children with head injury. Childs Nerv Syst 2000 Dec; 16(12): 862-6.
  • 35. Persistence of hypoxia on admission and CT scan finding of SAH, DAI, Brain edema are factors associated with poor outcome.14 Pediatric trauma score of <0 have poor outcome as also seen in our study.15 Reference: 14. Munch E C, Bauhuf C, Horn P. et al Therapy of malignant intracranial hypertension by controlled lumbar cerebrospinal fluid drainage. Crit Care Med 2001. 29976–981.981. 15. Campbell, John Creighton (2000). Basic trauma life support for paramedics and other advanced providers. Upper Saddle River, N.J: Brady/Prentice Hall Health
  • 36. Conclusion Road traffic Accident is the major cause of Pediatric mortality and morbidity in our country, followed by Falls. Need to follow “Start early, reach safely” axiom. India need to have “ThinkFirst For Kids program” . And also support United Nations “Decade of Action for Road Safety- 2011- 2020” theme.
  • 37. The ThinkFirst For Kids program represents a collaborative effort of educators, the ThinkFirst National Injury Prevention Foundation, the National Highway Traffic Safety Administration (NHTSA), the American Academy of Pediatrics, the Peace Education Foundation and professionals from the fields of psychology and psychiatry. The goal of the program is to increase knowledge and awareness among children in grades 1-3 of the causes and risk factors of brain and spinal cord injury, injury prevention measures, and the use of safety habits.
  • 38. The United Nations General Assembly has proclaimed the period 2011-2020 as the Decade of Action for Road Safety, “with a goal to stabilize and then reduce the forecast level of road traffic fatalities around the world by increasing activities conducted at the national, regional and global levels”.
  • 39.
  • 40. Acknowledgement Thankful to my Guides- Dr. Subodh Raju, Dr. M. A. Jaleel To our Dean DNB- Dr. Q. Hassan To Managing Director - Dr. Shashidhar Kamineni Sir and KHL, LB Nagar staff. To my colleagues – Dr. Renuka Sharma, Dr. S. Ramesh. Dr. Harikishor Reddy To Medical Records Section – Mr. Kishor, To Pediatric and Neurosurgery department staff To my wife – Dr. Sumedha Anjankar and my parents Dr. Deepak and Vidhya Anjankar