https://www.snmclub.com/presentation Nuclear Medicine - Cardiac PET/CT -   Advanced hybrid imaging modality - Sarah Y. Farhood Nuclear Cardiology

1. Sarah Y. Farhood
Nuclear Cardiology

2. Outlines :
 What is Cardiac PET ?
 How does a PET cardiac work ?
 What is Cardiac CT?
 Cardiac PET/CT
 Advantages
 Disadvantages
 Mobile PET/CT

3. Cardiac PET
 “ Positron Emission Tomography”
 It’s is a noninvasive nuclear imaging test. It uses
radioactive tracers (called radionuclides) to produce
pictures of your heart.
 allows quantification of
cardiac perfusion (physiology).
http://www.fac.org.ar/scvc/llave/image/macha
c/machf5b.jpg

4. How does Cardiac PET work ?
 A radioactive tracer is injected into the bloodstream.
 The tracers are mostly natural body compounds such
as water , ammonia or glucose
 These compounds are labeled with radioactive
material
 Radioactive material target the heart muscle
(mycardium) which produce energy and detected by
gamma camera

5. PET Radioisotopes
Rubidium-82 Chloride
Nitrogen-13 ammonia
Oxygen-15 water
F-18 FDG

6. What is Cardiac CT?
 “ Computed Tomography”
 It’s a painless test that look for the anatomy of the
heart using X-ray machine.
 X-ray machine will move around the patient and take
image for each view of the heart.
 These images are combined to create a 3-D image.
 Sometimes Iodine-based dye is injected to the vein to
highlight the coronary arteries ( angiography)

7. Cardiac CTA angiography
https://rpop.iaea.org/RPOP/RPoP/Content/InformationFor/HealthProfessionals/1
_Radiology/cadicCTEn.gif

8. Cardiac PET/CT
 This advanced hybrid modality allows physician to
examine the myocardium perfusion as well as the
assessment of coronary anatomy.
 These two modalities done in a single session of less
than 45 minutes.
http://jnm.snmjournals.org/content/48/7/1112/F1.large.jpg

12. Mobile PET/CT

13. Advantages of PET/CT
 Allow physicians to examine the myocardium function
as well as the coronary anatomy .
 Obtaining higher quality of images .
 Decrease the rate of misdiagnosis and false-positive.
 By identifying a coronary lesions to area of ischemia in
fusion of anatomical and functional images, treatment
strategies can be made.
 Less time

14. Disadvantages of PET/CT
 Radiation burden is a concern
 Less available
 Costly
 Greater maintenance costs
 Short half-lives of radioisotopes
 Some of the isotopes require on-site cycltron.

16. References
 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC28285
69/
 http://www.heart.org/HEARTORG/Conditions/Heart
Attack/SymptomsDiagnosisofHeartAttack/Positron-
Emission-Tomography-PET_UCM_446359_Article.jsp
 http://www.nhlbi.nih.gov/health/health-
topics/topics/ct
 http://www.healthimaging.com/topics/diagnostic-
imaging/cardiac-petct-practice