Presentation about Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infection. Made By: Santiago Ocampo, Maria Monica Noguera.

1. Presented by:
Maria Monica Noguera
Santiago Ocampo Buitrago.
Medical students, third semester.
UPB, Medellin

2. Staphylococcus pseudintermedius
Family: Staphylococcaceae
Gender: Staphylococcus
Coco
Dog´s skin microbiota, mucous membranes
Reported by: Hajek,
1976

3. ¿Why?
• Frequency in the unnecessary use of antibiotics in the system.
• Don't to follow medical instructions
• Spontaneous genetic variation induced by the selective
pressure of antibiotics on germs
Germ resistance
to conventional
antibiotics is a
big health
emergency
The bacterium mutate and can
exert different mechanisms
for its subsistence and
protection against antibiotics
Methicillin and bacterial
resistance

4. Research about; Methicillin-resistant
Staphylococcus pseudintermedius
synthesizes deoxyadenosine to cause
persistent infection.

5. =PCR=
Amplify
sequences
Of:

6. =MLST=
Multilocus enzyme
electrophoresis

7. =SDS-PAGE=
Separate proteins
according to their
electrophoretic mobility:

8. =TLC=
Principle of partitioning
between two phases.

13. AUTHOR WHAT THE AUTHOR SAY AGREE WITH
Van Duijkeren E, Frank LA, Pires
Dos Santos T
“The global emergence and rapid dissemination of
MSRP is a serious health threat in veterinary and
human medicine”
Somayaji R, Lee J “Likewise, abscesses and related pathological
structures are the most common disease form
caused by S. pseudintermedius in man”
Thammavongsa V, Winstel V “Earlier work demonstrated that the combined
activity of S. aureus Nuc and AdsA triggers
formation of cytotoxic dAdo from NETs, which kills
phagocytes by targeting the purine salvage pathway
and non-inflammatory apoptosis”

14. Diagnostic methods
Pathogenicity + knowledge =
Treatments
Zoonoses
How this study
and the Molecular
biology, contribute
to the medicine: