Describe the therapeutic goal in treating acid-peptic disease. Solution The therapeutic goal in treating acid-peptic disease include the following: Relief from the symptoms such as pain that occurs in between meals in the middle or upper portion of stomach , bloating, heart burn anf nausea. Healing of the ulcer that has affected the mucosal part of esophagus, stomach and duodenum. Prevention of reoccurrence of the ulcer. Synthesis of drugs such as histamine H2-receptor antagonists. Synthesis of drugs such as proton-pump inhibitors (PPIs) that bind to H+,K+-ATPase irreversibly thereby blocking the final step of gastric acid secretion. Synthesis of antibiotics against H. pylori which can cause peptic ulcers..