endocrine and metabolic shock

1. Endocrine & Metabolic
shock
BHAVANA RAJANNA
89 A

3.  Endocrine shock may present as a combination of hypovolaemic, cardiogenic and distributive
shock.
 Causes of endocrine shock include hypo- and hyperthyroidism andadrenal insufficiency.
 Hypothyroidism causes a shock result of disordered vascular and cardiac responsiveness to
circulating catecholamines.
 Cardiac output fallsbecause of low inotropy and bradycardia.
 There may also be an associatedcardiomyopathy.Thyrotoxicosis may cause a high-output cardiac
failure.

5. Adrenal insufficiency
 Adrenal insufficiency crisis
 An adrenal crisis is a life-threatening condition in which your adrenal
glands don't make enough cortisol. Causes include damage to your
adrenal glands and other stressors. Symptoms include abdominal pain,
fatigue and weakness. Healthcare providers can diagnose an adrenal
crisis with different blood tests.
 Adrenal insufficiency usually presents with vague symptoms such as
weakness, fatigue, anorexia, weight loss, and hyperpigmentation as the
primary symptoms. Acute adrenal crisis can manifest with vomiting,
abdominal pain, and hypovolemic shock.

7. Hypothyroidism
 Hypothyroidism happens when the thyroid gland doesn't make enough thyroid
hormone. This condition also is called underactive thyroid. Hypothyroidism may not
cause noticeable symptoms in its early stages.
 Symptoms of an underactive thyroid
• tiredness.
• being sensitive to cold.
• weight gain.
• constipation.
• depression.
• slow movements and thoughts.
• muscle aches and weakness.
• muscle cramps.

8. How does hypothyroidism cause shock?
 Hypothyroidism causes muscle relaxation and the isovolumetric relaxation and contraction
time becomes prolonged and MPI increases indicating systolic and diastolic
dysfunction [8]. Only when Cardiac dysfunction is severe, cardiac out put can be decreased
enough to cause cardiogenic shock

11. Can diabetic ketoacidosis cause shock?
 Without insulin, your body begins to break down fat in attempt to
get the energy it needs, a process that ultimately results in a
dangerous buildup of acids, known as ketones, in your
bloodstream. When this happens, your body can go into
shock, and the acid buildup causes swelling in the brain.
 Shock in DKA is a combination of hypovolemia and sepsis. To
differentiate between the two is difficult and most of the time it
may be a combination of hypovolemia and sepsis.
 Hyperglycemia acts as an osmotic diuretic, causing severe fluid
and electrolyte losses, leading to hypovolemic shock if
untreated. Individuals with severe DKA may lose nearly 500 mEq
of Na+, Cl−, and K+, along with approximately 7 L of water in
24 hr.

13. What causes metabolic
shock?
 It forms when the body breaks down carbohydrates to
use for energy when oxygen levels are low. It can be
caused by: Cancer. Carbon monoxide poisoning.

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